Clinical trials: Functional Disorder
Memory Disorders
AIT-082 Phase 1B Study
AIT-082 is a novel small molecule that crosses the blood-brain barrier to enhance nerve function by increasing levels of neurotrophic growth factors and encouraging nerve sprouting in the brain.
- Trial name
- NCT00000180
- Testing
- AIT-082
- Where
- 4 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Bone Disorder
Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.
- Trial name
- OSCAR (NCT06444503)
- Testing
- Biological samples, Biological
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Toulouse
Neurogenic Bladder Disorder, Spina Bifida
Complications of Bladder Augmentation in Children
The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood.
- Conditions
- Neurogenic Bladder Disorder, Spina Bifida, Complications of Surgical Procedures or Medical Care, Child, Only
- Trial name
- AVPED (NCT06733194)
- Where
- France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Clermont-Ferrand
Native Right Ventricle Outflow Tract(RVOT) Dysfunction
VenusP-Valve™ System Long-term Follow-up 6-10 Years
The goal of this study is to assess the long-term safety, efficacy and performance of VenusP-Valve™ implantation. in all subjects who provided informed consent and received VenusP-Valve™ implantation in the VenusP-Valve™ system…
- Trial name
- NCT07531303
- Volunteers
- 55 people
- Sponsor
- Venus MedTech (HangZhou) Inc.
Bronchiectasis
Evaluation of Motor Imagery, Cognitive Function and Reaction Time in Children With Bronchiectasis
The aim of this study was to evaluate motor imagery ability, reaction time and cognitive function parameters in children with CF and non-CF bronchiectasis compared to healthy peers.
- Trial name
- NCT06630403
- Testing
- Demographic Data, Disease History, Pulmonary Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Hemophilia, Hemophilia A, Severe
Reliability and Validity of the Turkish Version of the PedHAL
This study aimed to establish the validity and reliability of the Turkish version of the Pediatric Haemophilia Activities List (short - PedHALshort) questionnaire.
- Conditions
- Hemophilia, Hemophilia A, Severe, Hemophilia B
- Trial name
- NCT05889754
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hasan Kalyoncu University
Hemiparesis, Hemiplegic Cerebral Palsy
The Impact of Robot Assisted Therapy and Metacognitive Skills Training for Children With Hemiparesis
The Occupational Therapy Department at Boston Children's Hospital is teaming up with MGH Institute of Health Professions to explore the benefits of using robot assisted therapy (Amadeo) and a problem solving approach (Active…
- Conditions
- Hemiparesis, Hemiplegic Cerebral Palsy, Hemiparesis;Poststroke/CVA
- Trial name
- NCT04309266
- Testing
- Amadeo by Tyromotion, Active Learning Protocol for Stroke
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Executive Functioning
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings.
- Trial name
- NCT06651086
- Testing
- Unstuck and On Target, Unified Protocol for Children
- Where
- 2 sites in United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Primary Ciliary Dyskinesia
Respiratory Physiotherapy Performed by Simeox In Patients With Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is characterized by impaired airway clearance and mucus stagnation. This results in recurrent upper and lower respiratory tract infections often leading to chronic inflammation and, if not treated…
- Trial name
- NCT04793724
- Testing
- Simeox, PARI O PEP
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Chronic Obstructive Pulmonary Disease
Combination of NHF and Nebulizer on Lung Function in COPD
This study will prove to concept of effectiveness of NHF in combination with a nebulizer on reversibility of lung function in COPD patients.
- Trial name
- AEROFLOW (NCT02885103)
- Testing
- Nasal high flow (NHF), Nebulizer
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Leipzig
Apnea, Respiration
Functional Bed Sheet Capturing Pressure Variation and Respiratory Effort Over Time
Apnea, a cessation in breathing is critical condition that affects the person regardless of age. In infants, an apneic state occurs when there is an absence of respirations for 20 seconds (Alvaro \& Rigatto, 2012).
- Trial name
- NCT03119103
- Testing
- Functional Bed Sheet
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Studio 1 Labs
Diaphragm Dysfunction
Point of Care Ultrasound to Evaluate Diaphragmatic Function in Children Undergoing Thoracic Surgery
In children undergoing pulmonary resection, the diaphragm function is evaluated using ultrasound before and after surgery to evaluate the incidence of diaphragm dysfunction after pulmonary resection.
- Trial name
- NCT04400370
- Testing
- Diaphragm ultrasound
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Hospital
Sickle Cell Disease
Vascular Function Intervention Trial in Sickle Cell Disease
Sickle cell disease (SCD) is the most common inherited disorder worldwide affecting 300,000 births annually, most occuring in sub-Saharan Africa (SSA) where poor detection and care result in high childhood mortality…
- Trial name
- V-FIT (NCT01718054)
- Testing
- Vascular ready-to-use supplementary food, Regular Ready-to-use supplementary food, Chloroquine
- Where
- Tanzania
- Volunteers
- 120 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Cerebral Palsy
Cognitive Functioning in Children and Adolescents With Cerebral Palsy
Background: Cerebral palsy (CP) is characterized by motor impairment but commonly involves more widespread difficulties, including cognitive impairment.
- Trial name
- CPCog-Youth-DK (NCT05921422)
- Testing
- Cognitive assessment
- Where
- 2 sites in Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autism Spectrum Disorder
Efficacy of Vivomixx on Behaviour and Gut Function in Autism Spectrum Disorder
The purpose of this study is to assess the effects of 3 months supplementation with the multi strain probiotic Vivomixx on the overall function, aberrant behaviours and frequency of gastrointestinal symptoms in children with…
- Trial name
- VIVO-ASD (NCT03369431)
- Testing
- Vivomixx
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- University College, London
Ataxia Telangiectasia
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis
Study design: Parallel group, placebo-controlled, dose-escalation each 2 months for 12 months. Dose based on percent (%) of calculated caloric intake.
- Trial name
- A-TC7 (NCT04513002)
- Testing
- Triheptanoin
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- The University of Queensland
Sepsis
Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
The purpose of this study is to determine whether inhaled nitric oxide is an effective treatment for microcirculatory dysfunction and acute organ system failure in the early stage of sepsis therapy.
- Trial name
- NCT00608322
- Testing
- Inhaled nitric oxide
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Amblyopia, Strabismus
VISION-3D: Visual Skills Improvement With On-screen 3D Movies.
This clinical study investigates whether watching 3D films can help improve the vision of children with residual amblyopia (lazy eye), that is, those children who, despite having undergone usual treatments such as glasses or…
- Trial name
- VISION3D (NCT07301645)
- Testing
- Stereoscopic (3D) Movie Viewing, 2D Movie Viewing
- Volunteers
- 40 people
- Sponsor
- Universitat Politècnica de Catalunya
Partial Drug-resistant Epilepsy
High Resolution Imaging of Cerebral Vasculature by Functional Micro-Doppler Sonography During Brain Surgery
High Resolution Imaging of Cerebral Vasculature by Functional Micro-Doppler Sonography During Brain Surgery (ULYS)
- Trial name
- ULYS (NCT02090569)
- Testing
- Functional micro-Doppler Sonography (fmDS)
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier St Anne
Cerebral Palsy, Spastic
Effect of Robotic Assisted Therapy on Hand Functions, Grip Strength and Proprioception in Children With Hemiplegia
Statement of the problem: Does robotic assisted therapy have an effect on hand functions, grip strength and proprioception in children with hemiplegic cerebral palsy? Significance of the study: New technologies allow and promote…
- Trial name
- NCT07249866
- Testing
- Hand rehabilitation robotic gloves, occupational therapy
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
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