Clinical trials: Functional Disorder
Mild Cognitive Impairment
Making Memory Better for Seniors With Mild Cognitive Impairment
The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1)…
- Trial name
- NCT01532739
- Testing
- Cognitive training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Healthy, Vision; Disorder, Loss
Associations Between Vision and Brain Function
Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive…
- Trial name
- NCT04226729
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder
A Study of Randomized Sham-control Auricular TENS Unit Stimulation in Pediatric Functional Gastrointestinal Disorders
The purpose of this study is to see if using a micro-current through a device called a TENS (Transcutaneous Electrical Nerve Stimulator) unit helps to improve functional gastrointestinal disorder (FGID) symptoms in children by…
- Conditions
- Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder, Irritable Bowel Syndrome, Nausea
- Trial name
- NCT04247100
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Gisela Grotewold Chelimsky
Diabetes Mellitus, Type 1
Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes.
The goal of this clinical trial is to evaluate of the effect of phenofibrate on the functions of beta cells in children with new diagnosis of type 1 diabetes.
- Trial name
- PRIFEN (NCT05909800)
- Testing
- Phenofibrate
- Where
- 2 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Warsaw
Spinal Cord Injuries
Determine the Association Between the Level of SCI With Chronic Respiratory Symptoms, Measures of Pulmonary Function, and Respiratory Illness.
This study is using a standardized method to assess respiratory function in SCI in order to determine the association between level of SCI with chronic respiratory symptoms, measures of pulmonary function, and respiratory…
- Trial name
- NCT00011336
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
Depression
Working Memory Training for Dysphoric Students
Depression is associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02184481
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Nephrotic Syndrome
B Cells in Idiopathic Nephrotic Syndrome
The main aim of the present study is to determine whether reconstitution of different B-cell subpopulations can predict relapse after treatment with B-cell depleting antibodies in adult with NS, and whether specific B- or T-cell…
- Trial name
- BLADE (NCT05712369)
- Testing
- Blood sampling
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Speckle Tracking, Fetus Fetus
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using pulsed wave Doppler, Tissue Doppler and speckle tracking (strain and strain rate) between foetuses/neonates with a structural heart disease…
- Conditions
- Speckle Tracking, Fetus Fetus, Neonate, Structural Heart Disease
- Trial name
- STIPP (NCT05601375)
- Testing
- Echocardiography
- Where
- Netherlands
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Physical Functioning, Musculoskeletal Pain
Personalized Exercise Counseling to Promote Workability
The study design is a 2-arm randomized controlled trial with 6-month intervention period and follow-up at 6, 12 and 24 months among blue-color workers of Nokia City with reduced work ability and high number of musculoskeletal…
- Conditions
- Physical Functioning, Musculoskeletal Pain, Quality of Life, Physical Activity
- Trial name
- PEC-Nokia (NCT03854201)
- Testing
- Personalized Exercise Counseling (PEC)
- Where
- Finland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Peripheral Artery Disease
DUAL Pathway Inhibition to Improve Endothelial Function in Peripheral Artery Disease
Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis, causing patients to be at high risk of major adverse cardiovascular and limb events.
- Trial name
- DUAL-PAD (NCT04218656)
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet
- Where
- 2 sites in Netherlands
- Volunteers
- 159 people
- Sponsor
- Radboud University Medical Center
Nerve Injury
Autologous Fat in Peripheral Nerve Injury
The aim of this study is to assess the efficacy of autologous fat graft in enhancing peripheral nerve regeneration. The investigators hypothesize that fat grafting will allow for faster and greater recovery of motor and sensory…
- Trial name
- NCT04653129
- Testing
- Autologous Fat Grafting, Primary Nerve Repair
- Volunteers
- 44 people
- Sponsor
- Assiut University
Stroke
Left Atrial Function in Recurrent Stroke of Unknown Cause
Stroke is an important cause of disability and the third leading cause of death. Approximately 30 to 40 % of all strokes are estimated to be cryptogenic (i.e. no cause can be found).
- Trial name
- NCT02968329
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Hasselt University
Obesity/Therapy
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Glucagon-like peptide 1 receptor agonists (GLP-1RA), such as Ozempic and Wegovy, have been rapidly adopted for the treatment of obesity in both youth and adults.
- Trial name
- PLASTIC (NCT07021937)
- Testing
- Semaglutide 1.7mg subcutaneous
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Autistic Spectrum Disorder
Dates as a Functional Food for Autism
Autism spectrum disorder (ASD) is a lifelong developmental disability that includes deficits in social communication and social interaction and restricted, repetitive patterns of behavior, interests, or activities.
- Trial name
- NCT04261595
- Testing
- Dates fruit as functional Food, behavioral modification and stimulation, nutritional Guidance
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- National Research Centre, Egypt
Cerebral Palsy
Biomechanical Properties and Their Association With Balance and Functional Mobility in Children With Cerebral Palsy
This study aimed to investigate the differences in the biomechanical properties of the dorsal trunk and lower extremity muscles of children with unilateral spastic cerebral palsy compared with their typically developing peers…
- Trial name
- NCT05818839
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ilke KARA
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Chronic Granulomatous Disease
Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients
Treatment Study to assess of safety and efficiency of conditioning with Plerixafor and G-CSF as additional agents for prevention of graft failure after transplantation in patients with chronic granulomatous disease
- Trial name
- NCT03547830
- Testing
- Plerixafor, Gcsf
- Where
- Russia
- Volunteers
- 17 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Neurogenic Bowel, Spinal Cord Injuries (SCI)
Transcutaneous Spinal Cord Stimulation for Bowel Management in Individuals with Motor Complete Spinal Cord Injury
The primary goals of this pilot trial are to understand the feasibility and safety of thoracolumbar transcutaneous spinal cord stimulation for neurogenic bowel management in individuals with new onset, traumatic, cervicothoracic…
- Trial name
- NCT06801431
- Testing
- Transcutaneous spinal cord stimulation
- Volunteers
- 5 people
- Sponsor
- Nova Scotia Health Authority
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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