Clinical trials: Functional Motor Disorders
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Spinal Muscular Atrophy (SMA)
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
This study aims to find the correct dose of ARGX-119 for children with SMA. The study will also look at how safe the study drug is, how well it works, how it moves through the body, and how the immune system responds to it.
- Trial name
- Sparkle (NCT07287982)
- Testing
- ARGX-119 IV
- Where
- 28 sites in United States, Australia and 2 more
- Volunteers
- 60 people
- Sponsor
- argenx
Stroke, Exoskeleton
Effect of the Exoskeleton for Assisting Ambulatory Activities in People With Subacute Stroke
Background: Although rehabilitation activities, including physical therapy, are known to be beneficial for stroke patients, many patients still have poor walking function, especially after the acute phase of three months, where…
- Trial name
- NCT05837975
- Testing
- FREE Walk Exoskeleton, Traditional Rehabilitation
- Where
- Taiwan
- Volunteers
- 2 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Cerebral Palsy
Participation to Life of Children With Cerebral Palsy
Cerebral Palsy (CP) defined as a group of permanent impairments that is originating from non-progressive disorders that develop in the immature brain. CP leads activity limitations of movement and posture development.
- Trial name
- PLCC (NCT03191695)
- Testing
- Assessment via questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Hacettepe University
Epilepsy
Functional Coupling of Cortico-Cortical and Cortico-Muscular Connections During Motor Movements: An Electrocorticographic Study of Ipsilateral Motor Control
This study examines the relationship between a cerebral hemisphere and control of muscles on the same side of the body (ipsilateral control).
- Trial name
- NCT00036595
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Comparison of Task-oriented Activity Based Neurodevelopmental Principles and Gross Motor Task Training.
This study aims to find the comparison of task oriented activity based neurodevelopmental principles and gross motor task training on balance, trunk control and functional mobility in children with cerebral palsy.
- Trial name
- NCT05981287
- Testing
- Task-oriented activities based on NDT (TOA-NDT) principle and Conventional Physical Therapy, Gross motor task training and Conventional physical therapy (CPT)
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Motor Disorders, Neurodevelopmental Disorders
Neuromotor Development and Motor Related Health Care in Children with a High Risk Neonatal Period
The overall aim of the study is to evaluate the prevalence of motor- and neurological disorders (cerebral pares and other less severe motor disorders) in Swedish infants with a high-risk neonatal period and to elucidate whether…
- Conditions
- Motor Disorders, Neurodevelopmental Disorders, Premature Birth, Hypoxic-Ischemic Encephalopathy
- Trial name
- NCT06645717
- Volunteers
- 2,900 people
- Sponsor
- Karolinska Institutet
Muscle Loss, Protein
PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS
The investigators have designed a 2-center, pilot feasibility, randomized controlled trial (PROXIMUS) to determine the feasibility and safety of a larger multi center, randomized open-label trial comparing high protein combined…
- Conditions
- Muscle Loss, Protein, Mobility, Pediatric ALL
- Trial name
- PROXIMUS (NCT05296096)
- Testing
- Protein dosage and rehabilitation team delivered exercise prescription
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Boston Children's Hospital
Acute Lymphoblastic Leukemia
Effects of Core Stabilization Exercises in Children With Acute Lymphoblastic Leukemia
The goal of this clinical trial is to investigate the effects of core stabilization exercises applied in addition to the conventional exercise program on physical function, functional muscle strength, functional exercise…
- Trial name
- NCT06794762
- Testing
- Conventional exercises, Core stabilization exercises in addition to conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Karamanoğlu Mehmetbey University
Down Syndrome, Vibration Therapy
Comparative Study of Two Applications on Muscle Strength, Balance and Motor Function in Children With Down Syndrome.
To differentiate between the efficacy of virtual reality and whole-body vibration on muscle strength, balance and motor function in children with down syndrome.
- Conditions
- Down Syndrome, Vibration Therapy, Virtual Reality
- Trial name
- NCT07816120
- Testing
- virtual reality, whole body vibration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Neuromuscular Diseases
Reliability Study of a Motor Function Measure Digitalized Playful Completion Modules
Neuromuscular diseases include more than 200 rare disorders affecting muscles or the nervous system. Functional scales assessing motor function are tools allowing to measure the evolution of motor impairment of patients with a…
- Trial name
- MFM-Play (NCT05227274)
- Testing
- Items completion with or without a MFM-Play
- Where
- 10 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Childhood Cancer, Cognitive Impairment
Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
The purpose of this study is to create a rehabilitation program for children who survived posterior fossa tumors using the latest technology.
- Conditions
- Childhood Cancer, Cognitive Impairment, Motor Skills Disorders, Posterior Fossa Tumor
- Trial name
- NCT03951246
- Testing
- Cognitive and Motor Training
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Stroke, "Rehabilitation"
Determinants and Practical Significance of Change in Motor Ability, Functional Performance, and HRQOL After Stroke
This study has two purposes. First, the investigators will identify determinants of changes in motor ability, activities of daily living, and HRQOL after distributed Constraint-induced therapy for patients with stroke with the…
- Trial name
- NCT00776386
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Effect of a New Interactive Device on the Motor and Functional Abilities of Children With Bilateral Cerebral Palsy
Recent research has shown that interventions with assistive technologies lead to an improvement in the motor and functional abilities of children with cerebral palsy (CP).
- Trial name
- NCT04403464
- Testing
- HABIT-ILE with REAtouch®, HABIT-ILE without REAtouch®
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Université Catholique de Louvain
Neurodegenerative Diseases, Leukodystrophy
Home Exercise for Individuals With Neurodegenerative Disease
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
- Conditions
- Neurodegenerative Diseases, Leukodystrophy, Ataxia, LBSL
- Trial name
- NCT05443906
- Testing
- Home exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cerebral Palsy
Effect of Whole Body Vibration With Weighted Vest on Motor Function in Children With Spastic Diplegia
Whole body vibration has been widely used in rehabilitation of individuals with disabilities as well as children with cerebral palsy.
- Trial name
- NCT05606926
- Testing
- physical therapy program, whole body vibration (without extra weight vest), whole body vibration (with weight vest)
- Volunteers
- 30 people
- Sponsor
- Cairo University
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cerebral Palsy
The Follow Study of Speech Functions in Preschool Children With Cerebral Palsy: Clinical Measures and Acoustic Analysis
The aims of this study: 1. to investigate the difference in motor speech functions among children with cerebral palsy (CP) of different motor severities. 2.
- Trial name
- NCT02378987
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Duchenne Muscular Dystrophy
Aerobic Exercise in Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is the most common neuromuscular disease in childhood with an estimate incidence of 1 in 3500 to 5000 male births.
- Trial name
- NCT04173234
- Testing
- Aerobic Training, Home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Hacettepe University
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital