Clinical trials: GDM
Gestational Diabetes Mellitus (GDM), Microbiome, Human
A Probiotic Based Intervention in Pregnancies Complicated by GDM
This study is a single center randomized control trial of a probiotic based intervention in pregnancies complicated by gestational diabetes.
- Trial name
- ProbioGDM (NCT06794723)
- Testing
- 5-strain probiotic plus prebiotic natural health product
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Queen's University
Healthy, Vitamin D Deficiency
Can Correction of Low Vitamin D Status in Infancy Program for a Leaner Body Composition?
One in four infants are born with low amounts of vitamin D stored in their body. This study is designed to test whether improving vitamin D status quickly after birth helps infants to build muscle and to normalize growth.
- Conditions
- Healthy, Vitamin D Deficiency, Gestational Diabetes
- Trial name
- NCT02563015
- Testing
- cholecalciferol, Reference 400
- Where
- Canada
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- McGill University
Gestatiaonl Diabetes Mellitus, Insulin Resistance
Impact of Gestational Diabetes on Childhood Obesity
In this study, we aimed to investigate the relationship between obesity, glucose intolerance (insulin resistance), dyslipidemia and diabetes in children aged 5-12 born to mothers with Gestational Diabetes Mellitus (GDM) in…
- Conditions
- Gestatiaonl Diabetes Mellitus, Insulin Resistance, Dyslipaemia, Obesity &Amp; Overweight
- Trial name
- NCT07069296
- Testing
- blood samples were collected from participants, blood samples
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diabetes, Gestational, Obesity
Maternal GDM in Hispanic Youth: Risk for Obesity
Our studies are aimed at examining effects of intrauterine exposure to GDM on metabolic risks in Hispanic children. Our primary hypothesis predicts that intrauterine exposure to GDM will be associated with one or more of three…
- Conditions
- Diabetes, Gestational, Obesity, Insulin Resistance, Insulin Secretion
- Trial name
- NCT02668601
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pregnancy, Gestational Diabetes
Targeted Lifestyle Change Group Prenatal Care
To conduct a randomized trial to determine the effect of Targeted Lifestyle Change Group Prenatal Care (TLC) on maternal and neonatal outcomes in women at high risk for developing gestational diabetes mellitus (GDM).
- Trial name
- TLC (NCT04090307)
- Testing
- TLC Group Prenatal Care
- Where
- 2 sites in United States
- Volunteers
- 305 people
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes Mellitus
Gestational Diabetes Mellitus and Cardiometabolic Syndrome in Offspring
Gestational Diabetes Mellitus (GDM) has long been known as leading to macrosomias, neonatal hypoglycemias and other complications which are treatable and preventable.
- Trial name
- DG3 (NCT01490372)
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Université de Sherbrooke
Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus
Tongji Maternal and Child Health Cohort
This is a population-based study to obtain data for the evaluation of current used recommendations for weight gain during pregnancy released by IOM (2007) and investigate the association between maternal diet and the health…
- Conditions
- Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus, Diet Habit, Pregnancy Complications
- Trial name
- TMCHC (NCT03099837)
- Volunteers
- 8,649 people
- Sponsor
- Huazhong University of Science and Technology
Type II Diabetes Mellitus, Gestational Diabetes Mellitus
Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids
This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes.
- Trial name
- NCT03912363
- Testing
- Rotating fluids protocol, Insulin infusion protocol
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Offspring Exposed to GDM and Control
PREG - Offspring: Investigation of Children From Mothers With and Without Gestational Diabetes
Gestational diabetes is the most common complication during pregrancy. With a screening between week 24 and 28 of gestation women with gestational diabetes can be identified and treated.
- Trial name
- NCT04722900
- Testing
- intrauterine exposure to elevated glucose levels
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Diabetes Mellitus, Diabetes Mellitus, Type 1
An International Non-interventional Cohort Study to Evaluate the Safety of Treatment With Insulin Detemir in Pregnant Women With Diabetes Mellitus. Diabetes Pregnancy Registry
This study is conducted in Europe and Asia. The purpose of the study (Diabetes Pregnancy Registry) is to evaluate the safety of treatment with insulin detemir in pregnant women with diabetes mellitus.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01892319
- Testing
- insulin detemir, other injectable antidiabetic treatment regimens
- Where
- 93 sites in Croatia, Finland and 14 more
- Volunteers
- 2,446 people
- Sponsor
- Novo Nordisk A/S
Gestational Diabetes
Role of HbA1c in Predicting Adverse Pregnancy Outcomes
This study aims to determine the reference value of HbA1c that can be used to predict adverse pregnancy outcomes. These adverse outcomes include LGA fetus, shoulder dystocia, caesarean section, pre-term birth, pre-eclampsia and…
- Trial name
- NCT06676254
- Where
- Malaysia
- Volunteers
- 195 people
- Sponsor
- National University of Malaysia
Gestational Diabetes Mellitus in Second Trimester of Pregnancy
Evaluation of Serum Pentraxin 3 and High Sensitive CRP in Female Patients With Gestational Diabetes Mellitus in Second Trimester of Pregnancy
1. To assess the value of serum Pentraxin-3 and high sensitive CRP in females with normal pregnancy and females with gestational diabetes mellitus in second trimester of pregnancy. 2.
- Trial name
- NCT05846191
- Testing
- serum pentraxin 3 and high sensitive CRP
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gestational Diabetes Mellitus in Childbirth, Neurodevelopmental Disorders
Early Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
The prospective multicenter study GD-Brain provides a better knowledge on the basis of neurological impairment in children born to mothers with gestational diabetes (GDM).
- Trial name
- GD-BRAIN (NCT03032991)
- Where
- Spain
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Gestational Diabetes
Metformin Versus Insulin in Gestational Diabetes
Gestational diabetes is traditionally treated with insulin. Metformin is a peroral drug used worldwide in the treatment of type 2 diabetes and also in a few studies on patients with gestational diabetes.
- Trial name
- NCT01240785
- Testing
- metformin, insulin
- Volunteers
- 221 people
- Sponsor
- Turku University Hospital
Pregnancy, Stress
Effects of Stress on Glucose Tolerance During Pregnancy
The objective of the study is to investigate the effect of stress on glucose tolerance during pregnancy. The main objectives of the study are to investigate if various measures of stress (stressful life events, the perceived…
- Conditions
- Pregnancy, Stress, Gestational Diabetes
- Trial name
- NCT01707784
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Gestational Diabetes Mellitus
Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring
The rapidly rising risk of gestational diabetes pregnant women demands that an effective diet strategy be developed due to the high risk of fetal overgrowth, which places the newborn at increased risk for childhood obesity and…
- Trial name
- CHOICE (NCT02244814)
- Testing
- Low Carbohydrate/Conventional, Choosing Healthy Options in Carbohydrate Energy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Gestational Diabetes Mellitus (GDM)
Screening for Dysglycemia During Postpartum Period in Women With GDM
Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood.
- Trial name
- NCT07489456
- Testing
- Whatsapp message
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes in Obese Pregnant Women
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Tissue Glucose, Body Composition
- Trial name
- eMOM (NCT03542071)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 2 people
- Sponsor
- Helsinki University Central Hospital
Pregnancy Complications, Gestational Diabetes
Shenzhen Birth Cohort Study
The Shenzhen Birth Cohort Study was set up to investigate the effect of early life environmental exposures on short- and long-term health consequences in Shenzhen, China.
- Conditions
- Pregnancy Complications, Gestational Diabetes, Obstetric Labor Complications, Neurodevelopmental Disorders
- Trial name
- NCT03830879
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Gestational Diabetes
A Study on the Use of Real -Time Continuous Glucose Monitoring (RT-CGM) in Gestational Diabetes
The purpose of this study is to examine whether RT-CGM (real time continuous glucose monitoring) use improves glucose control, maternal outcomes, and fetal outcomes in patients diagnosed with gestational diabetes.
- Trial name
- NCT04803357
- Testing
- Continuous glucose monitor
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Washington