Clinical trials: Gallbladder Disease
Gall Bladder Disease
Ultrasound Guided Percutaneous Cholecystostomy.
Surgical cholecystostomy has proven value in the management of both inflammatory and obstructive biliary tract disease
- Trial name
- NCT05927870
- Testing
- pigtail
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Endoscopic Papillary Balloon Dilation, Bile Duct Stones
Long-term Outcomes of Endoscopic Papillary Balloon Dilation for 8-12mm Bile Duct Stones: a Prospective Study
The investigators prospectively evaluated long-term outcomes of ELBPD+EST for CBD stones up to 8-12mm. EPBD+EST in patients with CBD stones up to 8-12mm appears to be associated with a very low (<3%) rate of long-term stone…
- Conditions
- Endoscopic Papillary Balloon Dilation, Bile Duct Stones, Endoscopic Sphincterotomy, Stone Recurrence
- Trial name
- NCT05191693
- Testing
- ERCP
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Venizelio General Hospital
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer
The intent of the proposed study is to describe the prevalence of the most common recurring mutations in BRCA1 and BRCA2, blmAsh , and the A636P MSH2 mutation among Ashkenazi Jewish individuals with a variety of cancer diagnoses.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT00588263
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid
Ejection Fraction of Normal Gall Bladder on Ultrasonography in Patients With Biliary Colic: Is it a Predictor of Cholecystectomy?
In this study investigators aim to evaluate gallbladder ejection fraction as a predictor for cholecystectomy.
- Conditions
- Gall Bladder Pain, Hepatobiliary Iminodiacetic Acid, Acalculous Cholecystitis
- Trial name
- NCT05587933
- Testing
- cholecystectomy, Antispasmodic
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gallbladder Disease
The Comparison of Single Incision Laparoscopic Cholecystectomy and Three Port Laparoscopic Cholecystectomy
Laparoscopic techniques have allowed surgeons to perform complicated intrabdominal surgery with minimal trauma. Laparoscopic cholecystectomy has been recognized since 1987 as the gold standard procedure for gallbladder surgery.
- Trial name
- NCT01772745
- Testing
- SILS cholecystectomy, TPCL cholecystectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Cholecystitis, Acute, Elderly Infection
Percutaneous Transhepatic Cholangiography (PTHC) in Acute Cholecystitis and Clinical Outcomes
In a setting of acute cholecystitis (AC) one of the treatment option is percutaneous transhepatic cholangiography (PTHC) drainage.
- Conditions
- Cholecystitis, Acute, Elderly Infection, Drain Abscess
- Trial name
- NCT03087747
- Testing
- Percutaneous cholecystostomy
- Where
- Croatia
- Sponsor
- University of Split, School of Medicine
Acute Cholecystitis
The Real World of Acute Cholecystitis
Meta-analysis of randomized controlled trials and population based studies in acute cholecystitis are in favor for early laparoscopic surgery versus a delayed operation several weeks later.
- Trial name
- REWO (NCT02796443)
- Testing
- Laparoscopic cholecystectomy (LC)
- Volunteers
- 1,729 people
- Sponsor
- Asklepios Klinik Langen
Cholangiocarcinoma, Biliary Stenosis
Contribution of the EyeMAX™ 11Fr (Micro-Tech) Digital Single-Operator Cholangioscope With a Wide Working Channel
Background and aims Digital single-operator cholangioscopy (DSOC) enhances biliary stricture diagnosis, but the collection of quality samples can be difficult due to the small diameter of the working channel.
- Conditions
- Cholangiocarcinoma, Biliary Stenosis, Bile Duct Stones, Bile Duct Stenosis
- Trial name
- EyeMAX-CREGG (NCT06933576)
- Testing
- DSOC EyeMAX 11Fr
- Where
- 5 sites in France
- Volunteers
- 28 people
- Sponsor
- Clinique Paris-Bercy
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Common Bile Duct Calculi
Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCP
The goal of this work is to assess the best time to perform LC combined with LCBD exploration and the feasibility and safety of such procedure in patients with combined GBS and CBDS after failure of ERCP extraction of CBD stones .
- Trial name
- NCT05823181
- Testing
- laparoscopy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gall Bladder Carcinoma
Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality
Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
- Trial name
- NCT07885800
- Testing
- histopathology of gall bladder
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Gallbladder Volvulus
Gallbladder Volvulus Diagnosed Intraoperatively: Case Report
85-year-old female patient presented with right upper quadrant pain of one day duration, diagnosed with acalculous cholecystitis, and intraoperatively diagnosed with gallbladder volvulus.
- Trial name
- NCT06050876
- Testing
- Laparoscopic cholecystectomy for gallbladder volvulus
- Where
- Lebanon
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Balamand
Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma
Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery
This randomized phase II trial studies how well trametinib or combination chemotherapy works in treating patients with refractory or advanced biliary or gallbladder cancer or that cannot be removed by surgery.
- Conditions
- Adult Cholangiocarcinoma, Advanced Adult Hepatocellular Carcinoma, BCLC Stage C Adult Hepatocellular Carcinoma, BCLC Stage D Adult Hepatocellular Carcinoma
- Trial name
- S1310 (NCT02042443)
- Testing
- Capecitabine, Fluorouracil, Laboratory Biomarker Analysis
- Where
- 295 sites in United States
- Volunteers
- 53 people
- Sponsor
- National Cancer Institute (NCI)
Cholecystitis, Gallbladder Diseases
Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study is to compare early postoperative outcomes of unselected consecutive patients underwent laparoscopic cholecystectomy (LC) under spinal versus general anesthesia.
- Trial name
- NCT02956252
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 1,500 people
- Sponsor
- Medical Park Gaziantep Hospital
Choledocholithiasis, Gallstone Migration
Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile…
- Conditions
- Choledocholithiasis, Gallstone Migration, Cholecystitis, Gallstone Pancreatitis
- Trial name
- NCT02461147
- Testing
- Cholecystectomy with intraoperative cholangiogram
- Where
- Switzerland
- Volunteers
- 161 people
- Sponsor
- University Hospital, Geneva
Acute Cholecystitis, Empyema of Gallbladder
Effects of Drainage in Laparoscopic Cholecystectomy
During laparoscopic surgery for an acutely inflamed gallbladder, most surgeons routinely insert a drain. However, no consensus has been reached regarding the need for drainage in these cases, and the use of a drain remains…
- Conditions
- Acute Cholecystitis, Empyema of Gallbladder, Abscess of Gallbladder
- Trial name
- NCT02027402
- Testing
- Laparoscopic cholecystectomy with drain insertion
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Seoul St. Mary's Hospital
Gallstone
Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis
Subtotal cholecystectomy (STC) is a valuable technique when severe inflammation, fibrosis, or anatomical variations obscure the critical view of safety essential for identifying the cystic duct and artery.
- Trial name
- NCT06969144
- Testing
- cholecystectomy
- Where
- Nepal
- Volunteers
- 1,149 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Hemolytic Disorders, Gallstones
The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders
It is well established that hemolytic diseases predispose patients to the development of pigment gallstones. Gallstones are noted in at least 5% of children under the age of 10 years, increasing to 40-50% in the second to fifth…
- Trial name
- NCT02472509
- Testing
- Ursodeoxycholic Acid
- Where
- Israel
- Volunteers
- 3 people
- Sponsor
- Shaare Zedek Medical Center
Cholecystectomy
HOW TO PERFORM SAFELY CHOLECYSTECTOMY FOR ACUTE CHOLECYSTITIS
The aim of this manuscript is to illustrate a new method permitting safe cholecystectomy in terms of complications with respect to the common bile duct (CBD).
- Trial name
- NCT05744999
- Testing
- Coconut technique
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- University of Catania