Clinical trials: Gastro Intestinal Bleeding
Liver Cirrhosis, Esophageal Varices
Two-dimensional Shear-Wave Elastography Evaluate Esophageal Varices Bleeding Risk of Liver Cirrhosis
The purpose of this retrospective study was to investigate the diagnostic performance of 2D-SWE for predicting the presence of esophageal varices and high-risk varices in patients with liver cirrhosis.
- Conditions
- Liver Cirrhosis, Esophageal Varices, Liver Stiffness
- Trial name
- NCT03989973
- Testing
- Gastroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- West China Hospital
Coronary Heart Disease, Acute Coronary Syndrome
Cohort Study of Clopidogrel and Proton Pump Inhibitors
Patients who have experienced and survived non-ST segment elevation acute coronary syndromes are often prescribed a combination of aspirin and clopidogrel to thin the blood and prevent further acute coronary episodes.
- Conditions
- Coronary Heart Disease, Acute Coronary Syndrome, Drug Interactions, Clopidogrel
- Trial name
- NCT01231867
- Where
- United Kingdom
- Volunteers
- 24,471 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Acenocoumarol for the first…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947985
- Testing
- Rivaroxoban (Xarelto, Bay59-7939), Standard of care
- Where
- Netherlands
- Volunteers
- 208,958 people
- Sponsor
- Bayer
Abdominal Pain, Inflammatory Bowel Diseases
Examining the Effect of Ondansetron on Bowel Prep Success
This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient…
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea
- Trial name
- NCT05439772
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- State University of New York - Downstate Medical Center
Colon Cancer, Colorectal Cancer
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there may be a problem within the…
- Trial name
- NCT05329870
- Testing
- SNP array
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Duodenal Ulcer Bleeding
Prophylactic Injection Therapy Reduces Recurrent Bleeding In Forrest Type IIb Duodenal Ulcers
The purpose of this study is to determine whether prophylactic injection therapy reduces recurrent bleeding rate for duodenal ulcers which has the endoscopic stigmata of recent bleeding.
- Trial name
- NCT01471496
- Testing
- prophylactic injection therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Upper Gastrointestinal Variceal Bleeding in Cirrhotic Patients
Predictive and Prognostic Significance of Age,Blood Tests,Comorbidities(ABC) Score,Cologne Watch(C-watch)Score and Rockall Score for Risk of Variceal Re-bleeding Among Cirrhotic Patients
Introduction Portal hypertension is a common complication of liver cirrhosis and is often underestimated in clinical diagnosis. The incidence of portal hypertension is approximately 20% to 98% in patients with cirrhosis (Wu et…
- Trial name
- NCT06335186
- Testing
- upper endoscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
UGI Bleed
Comparison of Risk Scores in Upper Gastrointestinal Bleeding
The goal of this prospective observational study is to compare the Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score in predicting outcomes among patients with upper gastrointestinal bleeding (UGIB).
- Trial name
- NCT07819942
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Liver Cirrhosis, Portal Hypertension
Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis
Terlipressin is the mainstay drug for the treatment of acute variceal bleeding in liver cirrhosis. According to the drug instructions, intravenous bolus infusion is the standard approach of terlipressin.
- Conditions
- Liver Cirrhosis, Portal Hypertension, Variceal Hemorrhage, Bleeding
- Trial name
- NCT03130127
- Testing
- Terlipressin
- Volunteers
- 40 people
- Sponsor
- General Hospital of Shenyang Military Region
Gastrointestinal Bleeding
Haemorrhage Alleviation With Tranexamic Acid- Intestinal System
Severe bleeding in the digestive system is a common symptom of many diseases. Each year, about 50,000 people end up in British hospitals because of this problem and about 5,000 of them die.
- Trial name
- HALT-IT (NCT01658124)
- Testing
- Tranexamic Acid
- Where
- United Kingdom
- Volunteers
- 12,009 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Gastrointestinal Bleeding, Acute Coronary Syndrome
Factors Contributing To Cardiovascular Morbidity and Mortality in Patients With Gastrointestinal Bleeding
The rate of complication and death of patients with acute digestive tract bleeding is increased in the setting of acute coronary heart disease.
- Trial name
- NCT00401908
- Where
- United States
- Sponsor
- Maimonides Medical Center
Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding
Endoscopic Variceal Ligation in Children
This is an ambispective single-center cohort study of pediatric patients with portal hypertension and esophageal varices. The study was designed to evaluate the efficacy and safety of primary prophylaxis with endoscopic variceal…
- Conditions
- Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding, Endoscopy, Child
- Trial name
- NCT03943784
- Testing
- Endoscopic Variceal Ligation, Non-Selective Beta-Blocking Agent
- Volunteers
- 60 people
- Sponsor
- Hospital Vall d'Hebron
Acute Gastrointestinal Bleeding
Safety and Efficacy of Prophylactic Arterial Embolization in the Treatment of Angiography-negative Acute Upper Gastrointestinal Bleeding
Guided by clinical problems, this study focused on the problems encountered in clinical practice, with the interventional treatment of emergency gastrointestinal bleeding as the breakthrough point, and focused on the dilemma of…
- Trial name
- NCT05550649
- Testing
- embolization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai 10th People's Hospital
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Pediatric Acute Gastrointestinal Bleeding Registry
The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding.
- Trial name
- TRIAGE (NCT03090945)
- Testing
- This is an obsevational cohort study
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Gastric Cancer, Pancreatic Cancer
Study of Tranexamic Acid for Reducing Blood Requirement in Patients Undergoing Major Gastro-intestinal Surgery
Primary objective of the study is to compare requirement of blood transfusion and mortality in patients receiving Tranexamic acid (Cyklokapron®) and those not receiving it.
- Conditions
- Gastric Cancer, Pancreatic Cancer, Hepatocellular Cancer, Colon Cancer
- Trial name
- TMGS (NCT01655641)
- Testing
- Tranexamic acid, Standard of care
- Where
- Nepal
- Volunteers
- 118 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Upper Gastrointestinal Bleeding
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
The non-variceal upper gastrointestinal bleeding is defined as gastrointestinal bleeding located proximal to the angle of Treitz, whose cause is not related to esophagogastric varices or gastropathy of portal hypertension.
- Trial name
- NCT02537353
- Testing
- Metal clips, Hemospray, Endoscopy Exam
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Neutral Temperature, Bloody Stool
Temperature of Extremities and Necrotizing Enterocolitis
Bloody stool and necrotizing enterocolitis(NEC) is two main focus in non-neonatal intensive care unit ward and usually lead to longed duration of hospitalization.
- Conditions
- Neutral Temperature, Bloody Stool, Necrotizing Enterocolitis
- Trial name
- NCT04801537
- Testing
- normal body temperature and warm extremities, normal body temperature and cold extremities
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Gastrointestinal Hemorrhage
Artificial Intelligent Clinical Decision Support System Simulation Center Study for Technology Acceptance
The purpose of this research study is to measure the effect on of a large language model interface on the usability, attitudes, and provider trust when using a machine learning algorithm-based clinical decision support system in…
- Trial name
- NCT05816473
- Testing
- LLM
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Upper Gastrointestinal Bleeding
A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01275937
- Testing
- Esomeprazole
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Taipei Medical University