Clinical trials: Glaucoma Surgery
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Severe-stage Glaucoma (Mean Deviation ≤ -20 dB)
CVL Risk After Severe Glaucoma Surgery
This retrospective cohort study analyzes risk factors for central visual loss (CVL) after severe-stage glaucoma surgery. The primary hypothesis is that 1) visual prognosis is determined primarily by early postoperative…
- Trial name
- NCT07237555
- Where
- South Korea
- Volunteers
- 523 people
- Sponsor
- Gangnam Severance Hospital
Primary Congenital Glaucoma
Visco-Circumferential-Suture-Trabeculotomy Versus Trabeculotomy
comparing outcomes of Visco-Circumferential-Suture-Trabeculotomy in primary congenital glaucoma to trabeculotomy
- Trial name
- NCT04683289
- Testing
- trabeculotomy
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Mansoura University
Glaucoma
Effectiveness of a Procedure for Previously Failed Glaucoma Surgery
Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years.
- Trial name
- NCT00347789
- Testing
- Glaucoma surgery- Bleb revision
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glaucoma Research & Education Group
Primary Open Angle Glaucoma
Results of Ocular Compression and Suture Release in Trabeculectomy and Combined Surgery
The use of ocular compression and suture release have helped to improve the safety and decrease the risks of glaucoma filtering surgery.
- Trial name
- NCT00327405
- Where
- United States
- Sponsor
- University of Cincinnati
Open Angle Glaucoma, Intraocular Pressure
An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol.
The purpose of this study is to evaluate long term safety and effectiveness of the STREAMLINE® SURGICAL SYSTEM
- Trial name
- NCT06230393
- Testing
- STREAMLINE® SURGICAL SYSTEM
- Where
- Costa Rica
- Volunteers
- 17 people
- Sponsor
- New World Medical, Inc.
Glaucoma Open-Angle, Glaucoma Eye
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in…
- Conditions
- Glaucoma Open-Angle, Glaucoma Eye, Glaucoma; Drugs, Glaucoma, Angle-Closure
- Trial name
- NCT04381611
- Where
- Switzerland
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Dr. Kaweh Mansouri
Congenital Glaucoma
Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ).
this study aim to compare the effect of different technique of airway managment during anaesthesia on the haemodynamics and intraocular pressure in pediatric patient undergoing congenital glaucoma surgery.
- Trial name
- Airway and IOP (NCT07504315)
- Testing
- laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion
- Volunteers
- 75 people
- Sponsor
- Sohag University
Pediatric Glaucoma
Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract
The aim of this study is to report the effectiveness of phacoaspiration when combined with angle surgery in preventing postoperative glaucoma following pediatric cataract surgery
- Trial name
- NCT05401760
- Testing
- Group A :combined phacoaspiration and angle surgery, Group B : phacoaspiration only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Glaucoma
Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C
A clinical trial to establish the long term response of using intraoperative 5-fluorouracil (5-FU) versus mitomycin C (MMC) in trabeculectomy glaucoma surgery.
- Trial name
- NCT00346489
- Testing
- 5-fluorouracil, Mitomycin C
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Indiana University
Open Angle Glaucoma and Cataract
RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.
Post-operative cystoid macular oedema (CMO) is a common complication causing visual loss following routine cataract surgery. This complication is more prevalent in eyes with excessive inflammation as they heal from surgery.
- Trial name
- CMO (NCT03292796)
- Testing
- Prostaglandins
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Julie Dawson
Glaucoma Secondary, Congenital Cataract
Quantitatively Analysis of Fundus Structure Characteristics in Glaucoma Following Congenital Cataract Surgery
To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural association, and to assess…
- Trial name
- NCT05446077
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Congenital Cataract
Glaucoma After Congenital Cataract Surgery
To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.
- Trial name
- NCT04342052
- Where
- China
- Volunteers
- 351 people
- Sponsor
- Sun Yat-sen University
Congenital Glaucoma
Comparison Between Deep Sclerectomy and Traditional Trabeculotomy & Trabeculectomy in Congenital Glaucoma
The investigators hypothesize that deep sclerectomy in congenital glaucoma is a safer procedure and may yield better results than trabeculotomy trabeculectomy approach.
- Trial name
- NCT01460017
- Testing
- Deep Sclerectomy, Combined Trab
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Saud University
Glaucoma Following Pediatric Cataract Surgery
Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy in Pediatric Glaucoma Following Cataract Surgery.
This prospective case series evaluated the 12-month outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in children with glaucoma following cataract surgery (GFCS).
- Trial name
- (GATT in GFCS) (NCT07542522)
- Testing
- gonioscopy assissted transluminal trabeculotomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Glaucoma, Open-Angle
Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach
To measure surgical success of open vs closed conjunctiva with Xen implantation.
- Trial name
- NCT04406467
- Testing
- Xen Gel Stent
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Johns Hopkins University
Glaucoma, Glaucoma, Open-Angle
Dresden Glaucoma and Treatment Study (DGTS)
To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Angle-Closure, Glaucoma, Low Tension
- Trial name
- NCT02959242
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Technische Universität Dresden
Primary Congenital Glaucoma, Developmental Glaucoma
Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas
Newborn and children can be affected by two subgroups of this disease: (1) primary congenital glaucoma (PCG) or (2) developmental glaucoma (DG).
- Trial name
- STOP-Glaucoma (NCT04647929)
- Testing
- Santen PRESERFLO MicroShunt, Trabeculectomy
- Sponsor
- University of Zurich
Glaucoma, Open-Angle
An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)
The purpose of this study is to evaluate the safety and effectiveness of the OMNI® Surgical System in subjects who have undergone canaloplasty and trabeculotomy using OMNI® Surgical System without any concomitant surgery in…
- Trial name
- NCT04872348
- Testing
- OMNI® Surgical System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Sight Sciences, Inc.
Glaucoma Patients Scheduled for Trabeculectomy
Comparison of Two Method Antimetabolites Application on Corneal Function in Trabeculectomy Surgery
Application of antimetabolite agents such as mitomycin_c has improved trabeculectomy results and better control of intraocular pressure complications such as corneal endothelial cell loss.
- Trial name
- NCT01297803
- Testing
- Mitomycin_c
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences