Clinical trials: Gut Function
Irritable Bowel Syndrome, Dyspepsia Chronic
Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders
Abdominal pain (AP)-associated functional gastrointestinal disorders (FGIDs), particularly Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), are common in pediatrics, and no safe and effective treatment is available.
- Trial name
- NCT02566876
- Testing
- Mixture of three Bifidobacteria
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Federico II University
Sepsis, Intestinal Dysfunction
Effect of Different Feeding Method on Gastrointestinal Function of Septic Patients (DFM-GF Trial)
The intestine is the most vulnerable target organ in septic patients and is the first to be damaged organ in multiple organ dysfunction syndrome(MODS).
- Trial name
- DFM-GF (NCT03488940)
- Testing
- 24-hours group, 16-hours group, intermittent group
- Where
- China
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Fecal Incontinence in Children
Biofeedback Training Fecal Incontinence in Children
Fecal incontinence (FI) is the inability to control bowel movements, causing stool to leak from rectum it ranges from an occasional leakage of stool while passing gas to a complete loss of bowel control after the age of 4 years1.
- Trial name
- NCT04472923
- Testing
- Traditional Treatment, Biofeedback
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Batterjee Medical College
Cystic Fibrosis, Irritable Bowel Syndrome
Neuromodulation for Children With Cystic Fibrosis Experiencing Chronic Abdominal Pain
Chronic abdominal pain is extremely common in individuals with Cystic Fibrosis (CF). Therapy for chronic abdominal pain is very limited and generally consists of osmotic laxatives or drugs that are used to treat irritable bowel…
- Conditions
- Cystic Fibrosis, Irritable Bowel Syndrome, Chronic Pain
- Trial name
- NCT05515250
- Testing
- Use of neurostimulation device
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- St. Louis University
Cognitive/Functional Effects, Colorectal Cancer
Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.
- Conditions
- Cognitive/Functional Effects, Colorectal Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00410618
- Testing
- cognitive assessment, magnetic resonance imaging, management of therapy complications
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Arizona
Inflammatory Bowel Diseases, Psychological
Stress in Inflammatory Bowel Disease
This is a prospective, assessment-based study to examine the relationship between psychophysiological functioning and psychological symptoms in youth newly diagnosed with inflammatory bowel disease (IBD) compared to healthy…
- Trial name
- NCT05202418
- Testing
- Biofeedback Enhanced Treatment
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Epidural Anesthesia, Infection
The Effect of Combined General-epidural vs General Anaesthesia on Postoperative Gastrointestinal Surgery
Sixty neonates and infants will be enrolled and randomised into two groups of n=30 each . For their surgical procedures, one group general (GA) anaesthesia the second group will receive a combined general and epidural anaesthesia…
- Conditions
- Epidural Anesthesia, Infection, Infant, Newborn, Diseases
- Trial name
- NCT03056261
- Testing
- Combined general and epidural, General anaesthesia
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Obesity and Overweight, Breast Cancer Survivorship
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
Obesity can pose significant challenges to maintaining long-term health in cancer survivors by increasing their risk of cancer coming back.
- Trial name
- NCT07032545
- Testing
- Broccoli microgreen (BMG)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
Fecal Incontinence, Neurogenic Bowel
A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children
There is a surgical procedure to help children with intractable fecal incontinence gain continence for stool through construction of a tube that connects the abdominal wall to the colon near or through the appendix.
- Trial name
- NCT02435069
- Testing
- Dose Response - NS and USP Glycerin - First Intervention, Effectiveness - NS and USP Glycerin - Second Intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nemours Children's Clinic
Anxiety Disorder, Breast Cancer
S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors
RATIONALE: Physical activity, diet, and counseling may help breast and colorectal cancer survivors to lose weight and improve their quality of life.
- Conditions
- Anxiety Disorder, Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer
- Trial name
- NCT01453452
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- 58 sites in United States
- Volunteers
- 50 people
- Sponsor
- SWOG Cancer Research Network
Colon Disease, Functional Constipation
Non-invasive Assessment of Colonic Motility
The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures.
- Conditions
- Colon Disease, Functional Constipation, Electroenterography, Slow Transit
- Trial name
- non-CoMoti (NCT04624334)
- Testing
- Elektro-Entero-Graphy procedure, EEnG Questionnaire, Gold Standard Questionnaire
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Irritable Bowel Syndrome (IBS)
Collaborative Cognitive Behavioral Therapy / Hypnotherapy for Treatment of Pediatric Functional Gastrointestinal Disease
This program has been created to help patients with irritable bowel syndrome manage their symptoms and increase their functioning by using cognitive therapy skills and hypnosis.
- Trial name
- CAPP (NCT01966341)
- Testing
- CBT/ Hypnotherapy, Routine Management
- Where
- United States
- Sponsor
- Seton Healthcare Family
Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers
Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents
Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as…
- Conditions
- Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers, Inflammation
- Trial name
- NCT07125001
- Testing
- Ataulfo mango
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Irritable Bowel Syndrome, Abdominal Pain
Delivered Dietary Intervention for Children With Irritable Bowel Syndrome
The purpose of this study is to determine whether a specific diet may help children with irritable bowel syndrome.
- Trial name
- NCT01339117
- Testing
- Low fermentable substrate diet, High fermentable substrate diet
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Functional Abdominal Pain Syndrome
The Effects of Probiotics, Lactobacillus GG, in the Treatment of Abdominal Pain in Children With Functional Abdominal Pain Disorders
Recurrent or chronic abdominal pain is one of the common gastrointestinal problems in children. While most children do not have organic origins (so called functional abdominal pain disorders; FAPDs), the symptoms can nevertheless…
- Trial name
- NCT06310733
- Testing
- LGG
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Does Improving Vagal Tone Increase Mitochondrial Bioenergetics
This study evaluates the effect of auricular neurostimulation on mitochondrial bioenergetics and inflammation through vagal nerve modulation via non-invasive percutaneous electrical nerve field stimulator in children with…
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain Syndrome
- Trial name
- NCT03931330
- Testing
- Percutaneous neurostimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
Type 1 Diabetes
Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function
Data suggest that intestinal microbiota might be critically involved both in autoimmunity and in glucose homeostasis. An acetylated and butyrylated form of high amylose maize starch (HAMS-AB) that increases beneficial short chain…
- Trial name
- NCT04114357
- Testing
- Acetylated and Butyrylated High Amylose Maize Starch
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Fibromyalgia, Irritable Bowel Syndrome
Genetics of Fibromyalgia
The Fibromyalgia Family Study identifies and collects blood samples from families with two or more members affected with Fibromyalgia Syndrome (FMS).
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Depression
- Trial name
- NCT00071162
- Where
- 4 sites in United States
- Volunteers
- 560 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Constipation, Incontinence
The Long Term Outcomes After Pull-through of Long Segment Hirschsprung Disease
Hirschsprung disease (HSCR) is characterized by the absence of ganglion cells (aganglionosis) in the distal bowel extending proximally for varying distances that results in persistent spasm in the affected bowel and functional…
- Conditions
- Constipation, Incontinence, Hirschsprung Disease, Long-Segment, Long Term Adverse Effects
- Trial name
- NCT05461924
- Testing
- questionnaire survey
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Weibing Tang
Functional Abdominal Pain Syndrome
Reducing Pain and Anxiety Through Dietary Fiber Supplementation in Children With Abdominal Pain
Background - Mental health and pain problems in early childhood are major risk factors for serious mental health problems into adulthood.
- Trial name
- NCT04619095
- Testing
- Psyllium
- Where
- Canada
- Sponsor
- University of Calgary