Clinical trials: HIV Risk Behavior
HIV Prevention, PTSD and Substance Use Disorder
Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use
Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs.
- Trial name
- NCT03112369
- Testing
- Narrative Exposure Therapy (NET), Motivational Interviewing w/Skills Training (MIST)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Washington
Human Immunodeficiency Virus
Evaluation of Problem Management Plus in Pregnant Women With HIV in Kenya
This study includes secondary quantitative analysis, qualitative methods, and hybrid type 2 implementation-effectiveness pilot trial.
- Trial name
- Tatua (NCT05841797)
- Testing
- In-Person Program Management Plus (PM+), Mobile Program Management Plus (mHealth PM+)
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
HIV Infection, HIV Risk Behaviors
Peer Leaders as HIV Risk Reduction Change Agents Among Injection Drug Users (IDUs) in Ukraine
Using a randomized clinical trial (RCT), this study is designed to assess the effectiveness of HIV (human immunodeficiency virus) risk-reduction interventions targeting injection drug users (IDUs) in three Ukraine oblasts…
- Trial name
- NCT01159704
- Testing
- Peer Education Model, HIV Counseling and Education Model
- Where
- 3 sites in Ukraine
- Volunteers
- 2,304 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV/AIDS, Methamphetamine Abuse
Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use
This study is a single-arm, non-randomized pilot study. Eligible participants are newly enrolled participants in an outpatient methamphetamine treatment program, and study activities will take place contemporaneously with…
- Conditions
- HIV/AIDS, Methamphetamine Abuse, Depression
- Trial name
- NCT03864653
- Testing
- MoodGym
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Friends Research Institute, Inc.
Sexually Transmitted Infection
A Cognitive Behavioral And Structural HIV Prevention Intervention for Young Ugandan Sex Workers
This study develops and tests a behavioural and structural intervention to prevent unprotected sex among young female sex workers. Half the participants will receive the intervention and half will receive the standard of care.
- Trial name
- ZETRA (NCT03203200)
- Testing
- ZETRA cognitive behavioral structural
- Where
- Uganda
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV/AIDS, Sexually Transmitted Diseases
Comparison of Men's Prevention Apps to Research Efficacy
A randomized three arm control trial to examine the efficacy of two distinct apps (LYNX and MyChoices) developed for young men who have sex with men (YMSM) compared to standard of care (SOC) information about HIV testing and PrEP…
- Conditions
- HIV/AIDS, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
- Trial name
- COMPARE (NCT03965221)
- Testing
- LYNX, MyChoices
- Where
- 8 sites in United States
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
HIV, Alcohol Consumption
Mentor Moms+ Study
The goal of this study is to adapt an existing evidence based intervention for use in pregnant and lactating people (PLP) who use alcohol.
- Trial name
- (MM+) (NCT06962592)
- Testing
- MM+, Enhanced HIV attention control (eSOC)
- Where
- 2 sites in South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Adherence, HIV Risk Behaviors
The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1
The purpose of this study is to conduct a pilot study of Motivational Enhancement Therapy (MET), an empirically validated behavioral change strategy, with young adults who are HIV +.
- Conditions
- Adherence, HIV Risk Behaviors, Alcohol & Drug Use, Health Behaviors
- Trial name
- NCT00227825
- Testing
- Motivational interviewing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
HIV, Sexually Transmitted Diseases
Reducing HIV Risk Among Adolescents: Evaluating Project HEART
This study evaluates an educational web-based intervention designed to increase adolescent girls' motivation and skills to engage in safer sexual behavior (Project HEART: Health Education and Relationship Training).
- Trial name
- NCT02579135
- Testing
- Safer Sex, Growth Mindsets
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Sexual Behavior, Sexually Transmitted Diseases
Friendship Based HIV/STI (Sexually Transmitted Infections) Intervention for African American Females
The Project ÒRÉ intervention is a half-day community-based HIV/STI intervention program for friendship groups of adolescents that is tailored to African American culture.
- Conditions
- Sexual Behavior, Sexually Transmitted Diseases, HIV Infections
- Trial name
- NCT00109421
- Testing
- Project ÒRÉ
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sexual Behavior, Depression
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
The purpose of this study is to assess the feasibility and acceptability of a family-based preventive intervention designed to reduce sexual risk behaviors and depressive symptoms among South African adolescents and their…
- Trial name
- NCT02432352
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Brown University
Behavior
International Social Network Intervention
This grant involves 24 social networks of young men who have sex with men, Roma, and young high-risk heterosexual adult men and women living in Hungary, Bulgaria and Russia.
- Trial name
- NCT00838773
- Testing
- YMSM, YHA, ROMA
- Where
- 3 sites in Bulgaria, Hungary and 1 more
- Volunteers
- 1,292 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV Infections
HIV Prevention Within High-Risk Bulgarian and Hungarian Social Networks
This study will evaluate the effectiveness of peer-led HIV/sexually transmitted disease (STD)risk reduction educational counseling in reducing HIV risk behavior among the social networks of young men who have sex with men and…
- Trial name
- NCT00310973
- Testing
- Social Network Intervention
- Where
- 3 sites in Bulgaria, Hungary and 1 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV/AIDS
Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration
HIV prevalence among incarcerated youth living with HIV (YWH) is three times that of the general population and one in seven of all persons with HIV experience incarceration each year.
- Trial name
- LINK2 (NCT03584932)
- Testing
- LINK2 Youth Services Navigation Intervention
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of California, Los Angeles
Health Risk Behaviors
Sexually Active Adolescent Focused Education
SAAFE will be pilot tested in 2 geographically distinct areas (Washington, DC and Deep South) with 100 participants from each site to 1) primarily assess the efficacy of improved self-efficacy, knowledge about HIV/STIs and…
- Trial name
- SAAFE (NCT03646032)
- Testing
- SAAFE, Control
- Where
- 2 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Benten Technologies, Inc.
HIV, Sexually Transmitted Diseases
LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men
This study is testing the acceptability and feasibility of a highly interactive mobile application (app) to promote HIV/sexually transmitted infection (STI) testing and uptake of pre-exposure prophylaxis (PrEP) among young men…
- Conditions
- HIV, Sexually Transmitted Diseases, Risk Reduction, Pre-Exposure Prophylaxis
- Trial name
- NCT03177512
- Testing
- LYNX Mobile App
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Hiv
Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
The purpose of this program evaluation is to determine whether the Preventing AIDS Through Live Movement and Sound (PALMS) group-level intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing of…
- Trial name
- NCT00137644
- Testing
- Preventing AIDS Through Live Movement and Sound (PALMS)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
HIV/AIDS
Suubi4Her: Combination Intervention for Adolescent Girls Transitioning Into Adulthood in Uganda
This study examines the impact and cost associated with Suubi4Her, an innovative combination intervention that aims to prevent HIV risk behaviors among 15-17 year-old girls living in communities heavily affected by poverty and…
- Trial name
- NCT03307226
- Testing
- Youth Development Accounts (YDA), YDA + Multiple Family Groups (MFG)
- Where
- 2 sites in Uganda
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV Infections
Eliciting Affect in Teens in a Virtual World (Project AVATAR)
The purpose of this study is to determine whether immersive virtual reality technology is an effective intervention tool for HIV Prevention with adolescents.
- Trial name
- NCT02338063
- Testing
- Virtual Reality, Health Promotion
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital