Clinical trials: Head
Traumatic Brain Injury, Concussion, Brain
Understanding Concussion/Mild Traumatic Brain Injury
Using the Blink Reflexometer, athletes are scanned if they are potentially thought to have a concussion during a game or practice.
- Trial name
- NCT03381638
- Testing
- Blink Reflexometer
- Where
- 5 sites in United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Blinktbi, Inc.
Oral Lichen Planus, Oral Leukoplakia
Intra and Extra Oral Inspection of Oral Mucosa
Dental health professionals have a responsibility to perform routine intra- and extraoral inspection on their patients for detecting abnormalities.
- Conditions
- Oral Lichen Planus, Oral Leukoplakia, Erythroplakia
- Trial name
- NCT04079491
- Testing
- questionnaire survey
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Dalarna County Council, Sweden
Post-concussion Syndrome, Post-concussive Symptoms
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
PURPOSE: The long-term goal of this line of research is to develop rational, biologically based evidence for the treatment of post-concussion syndrome (PCS) in children.
- Conditions
- Post-concussion Syndrome, Post-concussive Symptoms, Traumatic Brain Injury, Concussion
- Trial name
- PLAYGAME (NCT01874847)
- Testing
- Melatonin, Sugar pill
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Recurrent Malignant Solid Neoplasm, Recurrent Melanoma
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors
This phase I trial studies the side effects and best dose of cabozantinib S-malate in treating younger patients with solid tumors that have come back or no longer respond to treatment.
- Conditions
- Recurrent Malignant Solid Neoplasm, Recurrent Melanoma, Recurrent Primary Central Nervous System Neoplasm, Recurrent Thyroid Gland Carcinoma
- Trial name
- NCT01709435
- Testing
- Cabozantinib S-malate, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 23 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- National Cancer Institute (NCI)
Head Trauma, Cognitive Change
Reducing Head Impact Exposure in Hawaii High School Football
This three-year study will determine the effectiveness of a helmetless tackling training intervention to decrease head impact exposure in Hawaiian high school football players.
- Conditions
- Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
- Trial name
- HuTT808 (NCT04020874)
- Testing
- HuTT-2x, HuTT-4x
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Esophageal Cancer
Endoscopic Submucosal Dissection Versus Esophagectomy for Early Esophageal Carcinoma
Endoscopic submucosal dissection (ESD) is a minimally invasive alternative to esophagectomy for early esophageal squamous cell carcinoma (EESCC), The data of EESCC patients who received ESD or esophagectomy were retrospectively…
- Trial name
- NCT06060106
- Testing
- Endoscopic submucosal dissection, Esophagectomy
- Where
- China
- Volunteers
- 191 people
- Sponsor
- Changhai Hospital
End-Stage Renal Disease, Living Donors
Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation
The purpose of this study is to observe in a randomized prospective study the effectiveness and toxicity of Thymoglobulin vs. Campath-1H used for induction therapy in recipients of living donor (LD) kidneys, compared with the…
- Trial name
- NCT01046955
- Testing
- Anti-Thymocyte Globulin vs Campath-1H vs Daclizumab
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Parotid Tumor
MRI and Fine Needle Aspiration in the Diagnosis of Parotid Tumors
What value is given to MRI diffusion and perfusion sequences in the diagnosis of parotid tumors? Is a fine needle aspiration associated with MRI systematically necessary? The aim of the research is to study the performance of…
- Trial name
- Parotid (NCT05152056)
- Where
- France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Strasbourg, France
Motor Vehicle Accidents, TBI (Traumatic Brain Injury)
Concussion in Motor Vehicle Accidents: The Concussion Identification Index
The primary goal of this study is to provide clinicians with a brief, patient self-administer instrument yielding a single composite score that reliably correlates with objective findings on standardized neurocognitive assessment…
- Conditions
- Motor Vehicle Accidents, TBI (Traumatic Brain Injury), Brain Contusion, Brain Injuries
- Trial name
- CIDI (NCT02858544)
- Testing
- The Concussion Identification Index, ImPACT
- Where
- United States
- Volunteers
- 1,790 people
- Sponsor
- Clionsky Neuro Systems Inc.
Concussion
Evaluation of an EEG Based Concussion System
This study will evaluate the accuracy of a new concussion system at detecting concussions. The investigators will be evaluating the degree to which data collected with the device agrees with a physician's determination of a…
- Trial name
- NCT03710109
- Testing
- EEG
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Concussion, Brain, Mild Traumatic Brain Injury
EyeBOX Concussion Study and Registry
The objective of this study is to further evaluate eye movements as an aid in the diagnosis of concussion / mTBI and the utility of eye movement assessment in the monitoring of symptoms over time after an initial diagnosis of…
- Trial name
- NCT03966404
- Testing
- EyeBOX device
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oculogica, Inc.
Brain Concussion, Post-Concussion Syndrome
Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes
The purpose of this investigation is to determine the effect of a weighted compression vest in addition to usual medical care and exercise rehabilitation on cardiovascular, neurocognitive, balance and anxiety measures in…
- Trial name
- NCT02362347
- Testing
- London Health Sciences Centre - Compression Vest, exercise
- Where
- 2 sites in Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Mild Traumatic Brain Injury
A Prospective Study of Brain Network Activation (BNA) Changes in High School Athletes Following Concussion
The main purpose of this study is to prospectively examine changes in Brain Network Activation(BNA)following concussion in high school athletes.
- Trial name
- NCT01673464
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Nasopharyngeal Carcinoma
Retrospective Study About Nasopharyngeal Carcinoma at C. S. Parc Tauli
Retrospective study of patients diagnosed with a nasopharyngeal carcinoma included in our data base care between June 1990 and September 2013.
- Trial name
- NCT02199132
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Corporacion Parc Tauli
Concussion, MTBI - Mild Traumatic Brain Injury
Online Treatment Recovery Assistance for Concussion in Kids
The investigators propose to develop a software platform, OnTRACK (Online Treatment Recovery Assistance for Concussion in Kids), for children and adolescents recovering from concussion or mild traumatic brain injury (mTBI).
- Trial name
- OnTRACK (NCT05065099)
- Testing
- Online Treatment Recovery Assistance for Concussion in Kids (OnTRACK)
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- Children's National Research Institute
MTBI - Mild Traumatic Brain Injury, Concussion, Mild
Controlled DTI Evaluations in High School Football and Female Soccer to Evaluate Efficacy of Jugular Compression Collar
The purpose of the study is to monitor longitudinal changes in brain structure between the preseason and postseason, in a population of football and soccer playing athletes wearing the Device and compared to a similar population…
- Trial name
- NCT04068883
- Testing
- Q collar
- Where
- 2 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Concussion, Mild
Mindfulness-Based Intervention for Mild Traumatic Brain Injury
Mindfulness is a promising tool which may foster adaptative interpersonal qualities to reduce the risk of persistent post-concussion symptoms.
- Trial name
- MBI-4-mTBI (NCT05105802)
- Testing
- Mindfulness-Based Intervention
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Children's Hospital of Eastern Ontario
Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional
Pediatric Integrative Manual Therapy in Babies With Deformational Plagiocephaly and Congenital Muscular Torticollis
This study evaluates the efficacy of Pediatric Integrative Manual Therapy in the treatment of positional plagiocephaly in infants.
- Conditions
- Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional, Congenital Muscular Torticollis
- Trial name
- NCT04672837
- Testing
- Pediatric Integrative Manual Therapy and educational therapy, Stretching and educational therapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Zaragoza
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