Clinical trials: Healthcare Associated Infection
Accidental Falls, Cross Infection (Hospital-Acquired Infections)
Impact of Primary Nursing on Nursing-sensitive Outcomes in Inpatients Units: a Multicentre Pre-Post Study
The aim of this quasi-experimental before-after study is to evaluate whether the implementation of the Primary Nursing (PN) pattern of care improves nursing-sensitive outcomes in adult inpatients and nurse-related outcomes across…
- Conditions
- Accidental Falls, Cross Infection (Hospital-Acquired Infections), Acute Care Unit
- Trial name
- PRIMARY (NCT07687251)
- Testing
- Primary Nursing
- Where
- 5 sites in Italy
- Volunteers
- 1,708 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Infection, Bacterial, Antibiotic Resistant Infection
Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.
Background: Due to anatomical restrictions, the inflammatory response to intra-cerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage.
- Conditions
- Infection, Bacterial, Antibiotic Resistant Infection, Diagnostic Self Evaluation, Meningitis, Bacterial
- Trial name
- NCT03252028
- Where
- 2 sites in Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fariba Nayeri
Blood Stream Infection
Topical Emollient Therapy
Almost all (99%) of the neonatal deaths occur in lower and middle income countries. Most of these deaths are attributable to prematurity and infection.
- Trial name
- NCT01396642
- Testing
- Topical Emollient
- Where
- 2 sites in Pakistan
- Volunteers
- 258 people
- Sponsor
- Aga Khan University
Ventilator-Associated Pneumonia Prevention and Intensive Care Nursing Care
Theory-Based Educational Program for VAP Prevention and Nursing Care in Intensive Care Units
Ventilator-associated pneumonia (VAP) is an important challenge in intensive care and requires nurses to apply evidence-based preventive practices consistently in mechanically ventilated patients.
- Trial name
- TSEP-VAP-2026 (NCT07820826)
- Testing
- Theory-Based Structured Educational Program, Usual Care
- Where
- Jordan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- JAWAD AHMAD ABU-SHENNAR
Cystic Fibrosis, Nontuberculous Mycobacterial Pulmonary Infection
Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria
Pulmonary NTM infection is recognized as one of the most challenging infections to treat among people with cystic fibrosis (PwCF), notable for prolonged treatment courses and often poor response to therapy.
- Trial name
- pHALT NTM (NCT05686837)
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Tracheostomy, Endotracheal Tube
Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.
Artificial airways, such as endotracheal tubes and tracheostomies, in the pediatric and neonatal intensive care units (PICU, NICU respectively) are lifesaving for patients in respiratory failure, among other conditions.
- Conditions
- Tracheostomy, Endotracheal Tube, Ventilator Associated Pneumonia, Tracheitis
- Trial name
- NCT06201130
- Testing
- Suctioning of artificial airway
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwell Health
Ventilator Associated Pneumonia
Ventilator Associated Pneumonia Care Bundle Prevention on Internship Students' Knowledge and Clinical Performance
The goal of this clinical trial is to determine the effect of a self-instructional module regarding ventilator-associated pneumonia care bundle prevention on internship students' knowledge and clinical performance in pediatric…
- Trial name
- NCT06090019
- Testing
- Routine PICU nursing care for children on mechanical ventilator., Self-instructional module for VAP care bundle prevention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Ventilator Associated Pneumonia ( VAP)
Impact of Oral Care on Ventilator Associated Pneumonia
The goal of this clinical trial was to find out whether cleaning the mouths of children in the Pediatric Intensive Care Unit (PICU) with toothbrushing and chlorhexidine lowers the chance of getting lung infections in patients on…
- Trial name
- OH-VAP (NCT07287566)
- Testing
- Toothbrushing + Chlorhexidine, Routine oral care + Chlorohexidine
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Healthcare-associated Infections
Trial of Positive Deviance in Inpatient Wards to Reduce Hospital Infections
Healthcare-associated infections (HAI) are a significant public health burden. Even with existence of recommendations on technical strategies to prevent these infections, there is a need for strategies to increase staff…
- Trial name
- NCT02244905
- Testing
- Positive Deviance, Standard-of-Care Infection Control approach
- Volunteers
- 16,876 people
- Sponsor
- University of Texas Southwestern Medical Center
PANDAS, PANS
The Unhide™ Project: Economic Impact Study of IVIG Treatment for PANS
The Economic Impact Study of IVIG treatment for PANS is a part of the Unhide™ Project, which is a research initiative developed by the Brain Inflammation Collaborative.
- Conditions
- PANDAS, PANS, PANS Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
- Trial name
- NCT06818656
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Brain Inflammation Collaborative
Staphylococcus Aureus
Mupirocin-Iodophor ICU Decolonization Swap Out Trial
The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the non-inferiority of two decolonization regimens: Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in…
- Trial name
- NCT03140423
- Testing
- Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization
- Where
- 137 sites in United States
- Volunteers
- 353,323 people
- Sponsor
- Harvard Pilgrim Health Care
Hospital Infection, Urinary Tract Infections
The Global Prevalence of Infections in Urology Study
Urology departments from all over the world are invited to join the Global Prevalence Study on Infections in Urology (GPIU-study) and the GPIU Prostate Biopsy Side Study.
- Trial name
- GPIU (NCT03665467)
- Where
- 4 sites in Germany, Hungary and 2 more
- Volunteers
- 2,000 people
- Sponsor
- European Association of Urology Research Foundation
Brain Injuries, Congenital Heart Disease
Protecting Brains and Saving Futures - the PBSF Protocol
Background: Multiple neonatal disorders are associated with risks of neurological injury. Thus, management of these infants should involve a coordinated approach to permit early diagnosis with improved clinical care.
- Conditions
- Brain Injuries, Congenital Heart Disease, Newborn Morbidity, Intraventricular Hemorrhage
- Trial name
- PBSF (NCT03786497)
- Where
- 2 sites in Brazil
- Volunteers
- 2,268 people
- Sponsor
- Protecting Brains Saving Futures
Hospital Infection
Application of Standardized Cleaning and Disinfection Mode of HFT Surface in Hospital Infection Prevention and Control
The scientific, feasible and effective mode of standardized cleaning and disinfection of ICU high-frequency contact surfaces is discussed and verified.
- Trial name
- NCT04920240
- Testing
- cleaning and disinfection mode for surfaces with high frequency contact, Routine procedure
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Health Care Associated Infection
Health Care Associated Infection Surveillance in NICU
Healthcare - Associated Infection Surveillance In Neonatal Intensive Care Unit of Assiut University Children's Hospital.The objective of study is to determine the incidence, infection sites, causative organisms and risk factors…
- Trial name
- NCT03254316
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Gehad Salah El-Den Mahmoud Mohammad
Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection
A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea
The purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients with difficult types of infections in the abdomen…
- Conditions
- Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection, Hospital-acquired Pneumonia
- Trial name
- NCT05733104
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Pfizer
Infectious Disease Transmission
Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit
This is a prospective, controlled; crossover study of daily bathing with no-rinse, 2% chlorhexidine gluconate (CHG) impregnated washcloths versus bathing with water/soap or water according to gestational age and weight (e.g.
- Trial name
- NCT02537964
- Testing
- washcloths impregnated with 2% chlorhexidine gluconate
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Shaare Zedek Medical Center
Nosocomial Infections
Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality
This 4-year cluster randomized controlled trial aims to determine whether implementation of Evidence-based Practice for Improving Quality (EPIQ) method can reduce hospital-acquired infection in Chinese Neonatal Intensive Care…
- Trial name
- NCT02600195
- Testing
- Evidence-based Practice for Improving Quality (EPIQ) method
- Where
- 24 sites in China
- Volunteers
- 15,600 people
- Sponsor
- Children's Hospital of Fudan University
Healthcare Associated Infection
Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2…
- Trial name
- MICH (NCT04770597)
- Testing
- Aranet4 Home CO2 monitor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Imelda Hospital, Bonheiden
Traumatic Brain Injury, Deep Vein Thrombosis
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
Whilst deep vein thrombosis (DVT) is common following traumatic brain injury (TBI), optimal timing and safety of pharmacological prophylaxis is uncertain. Paradoxically the harm associated with the occurrence of is also unclear.
- Conditions
- Traumatic Brain Injury, Deep Vein Thrombosis, Acute Lung Injury, Ventilator Associated Pneumonia
- Trial name
- TARDIS (NCT03937947)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- NHS Lothian