Clinical trials: Heart Infarction
Acute Myocardial Infarction
Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs
Methods: All patients <75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI).
- Trial name
- GuLLD (NCT02929550)
- Testing
- Well-controlled
- Volunteers
- 5,304 people
- Sponsor
- Karolinska Institutet
Contraception, Female Contraception
A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control
The purpose of the study is to use data from a health care information database to assess the risk of venous thromboembolism (blood clots), myocardial infarction (heart attacks), and stroke among women using a transdermal…
- Trial name
- NCT00377988
- Testing
- Transdermal Contraceptive System, Norgestimate-containing oral contraceptives with EE
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Heart Diseases, ASD - Atrial Septal Defect
Abbott Structural Heart Device Registry
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale
- Trial name
- SH-Registry (NCT06590467)
- Testing
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Where
- 36 sites in United States, Denmark and 8 more
- Volunteers
- 2,500 people
- Sponsor
- Abbott Medical Devices
Myocardial Infarction, Arrhythmia, Ventricular
MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients
The purpose of the study is to determine the usefulness of Microvolt T Wave Alternans (MTWA) testing of patients that have had a heart attack and have decreased pumping ability of the lower chamber of their heart.
- Conditions
- Myocardial Infarction, Arrhythmia, Ventricular, Ischemic Cardiomyopathy
- Trial name
- NCT00305214
- Testing
- T Wave Alternans Test
- Where
- 47 sites in United States
- Volunteers
- 405 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiovascular Diseases, Heart Diseases
Compliance in the Physicians' Health Study
To evaluate the relationships of compliance in taking aspirin or aspirin placebo with the risk of major cardiovascular endpoints, using data collected in the Physicians' Health Study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005404
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Myocardial Infarction
Effects of Percutaneous Coronary Intervention in Patients With Cardiac Arrest After Acute Myocardial Infarction: a 2-Year Study
The purpose of this study is To assess percutaneous coronary intervention 's effect on short- and long- term outcomes, and complication incidence in resuscitated victims of cardiac arrest after acute myocardial infarction
- Trial name
- NCT02576691
- Testing
- percutaneous coronary intervention
- Volunteers
- 2,363 people
- Sponsor
- Yuanli Lei
Dipeptidyl-peptidase-4, STEMI
Plasma Dipeptidyl-peptidase-4 Activities With No-reflow and Bleeding
Dipeptidyl-peptidase-4 (DPP4) is an important regulator of incretins and inflammation, and participates in the pathophysiological process of acute myocardial infarction (AMI).
- Conditions
- Dipeptidyl-peptidase-4, STEMI, PCI, No-reflow
- Trial name
- NCT02849691
- Volunteers
- 747 people
- Sponsor
- Chinese PLA General Hospital
Acute Myocardial Infarction, Pulmonary Hypertension
Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function
Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function.
- Trial name
- STIMULATE (NCT06186713)
- Testing
- This was an observational study, and no Intervention was given to the patients.
- Where
- China
- Volunteers
- 4,784 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Ventricular Fibrillation, Ventricular Tachycardia
Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans
In this study, we will compare the quality of life in veterans having ICD who attend the ICD support groups to those who do not.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- NCT00846417
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Diseases, Hypertension
Insulin and Biogenic Amines in Cardiovascular Disease
To determine the role played by insulin and biogenic amines in obesity-related hypertension and cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases, Obesity
- Trial name
- NCT00005194
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices
Relation of Total Ischemic Time to Repolarization Indices and Their Impact on Outcomes Among STEMI Patients Undergoing Primary PCI
1. Evaluate The impact of early versus late presentation on electrocardiographic ventricular repolarization indices. 2. To assess the association between repolarization indices among early, late presentation in relation to…
- Conditions
- ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices, Total Ischemic Time, Primary Percutaneous Coronary Intervention
- Trial name
- NCT07175259
- Testing
- Echocardiography
- Volunteers
- 500 people
- Sponsor
- Assiut University
ST Segment Elevation Myocardial Infarction
ST Segment Resolution After Primary Percutaneous Coronary Intervention.
To compare the ST segment resolution after primary percutaneous coronary intervention (PPCI) with and without thrombus aspiration in patients with ST segment elevation myocardial infarction as ST segment resolution is the best…
- Trial name
- STresolution (NCT03895983)
- Testing
- Percutaneous primary coronary intervention
- Volunteers
- 270 people
- Sponsor
- Assiut University
Acute Myocardial Infarction
Livalo Acute Myocardial Infarction Study
Statins are usually used in AMI patients due to its strong anti-lipidemic effect, pleiotropic effect and tolerable safety profiles.
- Trial name
- LAMIS (NCT00805714)
- Where
- 10 sites in South Korea
- Volunteers
- 1,128 people
- Sponsor
- JW Pharmaceutical
Cardiovascular Diseases, Coronary Disease
Physical Activity and Cardiovascular Disease Prevention
To provide new scientific information regarding the role of physical activity in primary and secondary disease prevention, particularly coronary heart disease (CHD).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005447
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
COVID, SARS-CoV-2
European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO
In the last 10 years, severe acute respiratory infection (SARI) was responsible of multiple outbreaks putting a strain on the public health worldwide.
- Conditions
- COVID, SARS-CoV-2, ARDS, Human, Refractory Hypoxemia
- Trial name
- EuroECMO-COVID (NCT04366921)
- Where
- 97 sites in Austria, Belgium and 17 more
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
ST Elevated Myocardial Infarction, Dual Antiplatelet Therapy
Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients
The study is a multi-centre, Open-label, Randomized Controlled, 1:1 trial comparing Prasugrel-based short DAPT (30-45 days) followed by Prasugrel monotherapy versus standard DAPT regimen in STEMI patients in terms of safety and…
- Trial name
- NCT05491200
- Testing
- Prasugrel based short DAPT, Prasugrel based standard DAPT, OCT guided revascularization
- Where
- 27 sites in Belgium, Czechia and 4 more
- Volunteers
- 1,656 people
- Sponsor
- Research Maatschap Cardiologen Rotterdam Zuid
Covid19, Myocardial Infarction
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This retrospective cohort study aims to characterise outcomes for patients treated on an intensive care unit (ICU) with COVID-19 in England and Wales, one year after discharge from hospital.
- Conditions
- Covid19, Myocardial Infarction, Stroke, Critical Illness
- Trial name
- OPTIC-19 (NCT04838106)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 319,600 people
- Sponsor
- University of Oxford
Angioplasty, Transluminal, Percutaneous Coronary
Effect of Atorvastatin Administration Before Primary Percutaneous Coronary Intervention
The purpose of this study to determine whether statin pretreatment decrease myocardial infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.
- Trial name
- NCT00610870
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 173 people
- Sponsor
- Samsung Medical Center
Coronary Heart Disease
China PEACE-Retrospective AMI Study
Coronary heart disease (CHD) and heart attacks pose a serious health risk to men and women, however the knowledge about the real-life AMI management in China is limited.
- Trial name
- NCT01624883
- Volunteers
- 18,000 people
- Sponsor
- China National Center for Cardiovascular Diseases