Clinical trials: Heart Rhythm Disorders
Bundle-Branch Block, Heart Septal Defects, Ventricular
Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
The most common congenital heart disease is the ventricular septal defect, and after surgical closure of a such defect, an arrythmia called the right bundle branch block, is very frequent.
- Trial name
- NCT01480908
- Testing
- Echocardiography at rest, Echocardiography during exercise, MRI at rest
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Paroxysmal Supraventricular Tachycardia
Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency Ablation
This study to investigate the effects of RF ablation on left atrial systolic function in patients with atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).
- Trial name
- NCT03348436
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruiqin xie
Cardiac Rhythm Disorder
EP Device Registry
This study will provide ongoing, high quality data on the safety, performance, and clinical benefits of Abbott's EP devices in a real-world setting.
- Trial name
- NCT04460209
- Testing
- Standard of Care
- Where
- 26 sites in Austria, Czechia and 8 more
- Volunteers
- 5,003 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation, Stroke
Echocardiographic Risk Factors of Stroke in Patients With Atrial Fibrillation
The goal is to review patients with known atrial fibrillation who suffered a stroke or transient ischemic attack (TIA) to incorporate any structural heart abnormalities into the overall clinical picture.
- Trial name
- NCT03824509
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- MaineHealth
Supraventricular Tachycardia
Sevoflurane and Isoflurane for RF or Cryo Ablation in Children.
In children, radiofrequency catheter ablation (RFCA) or cryoablation are highly effective treatments for supraventricular tachycardia treatment.
- Trial name
- NCT01216501
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Schneider Children's Medical Center, Israel
Cardiac Arrest
Biphasic Defibrillation Study: Trial to Compare Fixed Versus Escalating Energy
This study will compare the effect of constant low-level energy [150 joules] to an escalating energy [200-300-360 joules] regimen of biphasic waveform defibrillation on multiple patient outcomes.
- Trial name
- NCT00212992
- Testing
- Fixed lower-energy defibrillation, Escalating higher-energy defibrillation
- Where
- Canada
- Volunteers
- 221 people
- Sponsor
- Ottawa Hospital Research Institute
Tachyarrhythmia
Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)
The LEADR study is designed to assess the safety and efficacy of the Next Generation ICD lead. The LEADR LBBAP study is being conducted under the existing US FDA Investigational Device Exemption (IDE) for the Next Generation ICD…
- Trial name
- NCT04863664
- Testing
- Defibrillation (RV Implant), Defibrillation (LBBAP Implant)
- Where
- 55 sites in United States, Australia and 18 more
- Volunteers
- 998 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Warfarin for the first time…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947998
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Warfarin, Antiplatelet drugs
- Where
- United Kingdom
- Volunteers
- 50,299 people
- Sponsor
- Bayer
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Post Operative Arrythmia
Dexmedetomidine and Magnesium Sulfate in Preventing Junctional Ectopic Tachycardia After Pediatric Cardiac Surgery
to study the prophylactic effect of magnesium sulfate , dexmedetomidine or their combination in reduction the incidence of JETS postoperative
- Trial name
- NCT05554848
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital
Atrial Fibrillation
Retrospective Observational Registry of Patients With Atrial Fibrillation From Vigo´s Health Area
Registry of all consecutive patients with atrial fibrillation from Heath Area of Vigo, since 2013 to 2020, in order to study therapy, mortality, cardiovascular complications and bleeding events.
- Trial name
- CardioCHUVI-AF (NCT04364516)
- Testing
- Anticoagulation
- Where
- Spain
- Volunteers
- 15,000 people
- Sponsor
- Hospital Álvaro Cunqueiro
Arrhythmia
Long-Term Follow-Up of Patients Undergoing Catheter Ablation
The purpose of this study is to assess the long-term effects of catheter ablation procedures performed at the OU Medical Center.
- Trial name
- NCT00584558
- Testing
- Catheter Ablation
- Where
- United States
- Volunteers
- 2,420 people
- Sponsor
- University of Oklahoma
Paroxysmal Supraventricular Tachycardia
Pulsed Field Ablation for Paroxysmal Supraventricular Tachycardia（PSVT）
The purpose of this study was to explore the safety and efficacy of a Pulsed Field Ablation Device and Force Sensing Pulsed Field Ablation Catheter in the treatment of Paroxysmal Supraventricular Tachycardia.
- Trial name
- NCT05770921
- Testing
- Pulsed Field Ablation Device and Force Sensing Pulsed Field Ablation Catheter
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Ningbo No. 1 Hospital
Cardiovascular Diseases, Atrial Fibrillation
Pharmacogenetics and Cardiovascular Events
To assess interactions between selected cardiovascular medications and genes in the incidence of heart attack, stroke, and atrial fibrillation, an irregular heartbeat.
- Conditions
- Cardiovascular Diseases, Atrial Fibrillation, Cerebrovascular Accident, Heart Diseases
- Trial name
- NCT00094198
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Heart Diseases
Electrophysiological Effects of Late PCI After MI
The purpose of this study is to determine if opening blocked arteries with heart balloons and stents prevents heart rhythm problems in individuals 3 to 28 days after a heart attack.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Coronary Disease
- Trial name
- NCT00119847
- Testing
- PCI, Optimal Medical Therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Maryland, Baltimore
Transcatheter Aortic Valve Replacement
Prognostic Factors in NOP-LBBB After TAVI
The goal of this observational study is to find prognostic factors in patients with a new-onset persistent left bundle branch block (NOP-LBBB) after transcatheter aortic valve implantation (TAVI).
- Trial name
- ProgNOP-LBBB (NCT05654792)
- Testing
- Transcatheter aortic valve implantation
- Volunteers
- 230 people
- Sponsor
- Central Hospital, Nancy, France
Atrial Fibrillation
Japanese Pradaxa PMS, Long Term
The study objective is to confirm appropriate use and safety profile of Prazaxa® Capsules in real-world setting after the availability of idarucizumab
- Trial name
- NCT03175198
- Testing
- Prazaxa® Capsules
- Where
- Japan
- Volunteers
- 5,660 people
- Sponsor
- Boehringer Ingelheim
Cardiovascular Diseases, Arrhythmias, Cardiac
Multicenter Evaluation of Patients Using LATITUDE Monitoring System
The Multitude is a registry of patients who receive commercially available CIEDs that remotely communicate through the LATITUDE monitoring system and transfer data to a central database.
- Conditions
- Cardiovascular Diseases, Arrhythmias, Cardiac, Heart Failure, Sudden Cardiac Death
- Trial name
- Multitude (NCT06311149)
- Where
- 3 sites in Italy
- Volunteers
- 20,000 people
- Sponsor
- University Hospital of Ferrara
Atrial Fibrillation
Safe Use of New Oral Anticoagulants in Ablation for Atrial Fibrillation
Use of new oral anticoagulants (NOAC) in patients before and after catheter based pulmonary vein isolation (PVI) is still controversial.
- Trial name
- NCT02569255
- Testing
- Pulmonary venous ostia isolation
- Volunteers
- 234 people
- Sponsor
- Private Hospital Heart Center Varde
Atrial Fibrillation
Left Atrial Mechanical Function Improvement After Atrial Fibrillation Catheter Ablation
The objective of the study was to estimate the efficacy of telmisartan and amlodipine combination on the restoration of left atrial mechanical function after atrial fibrillation catheter ablation.
- Trial name
- NCT02734355
- Testing
- Telmisartan 80 mg and amlodipine 5 mg
- Volunteers
- 64 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia