Clinical trials: Hemangioma, Capillary
Bleomycin Adverse Reaction
Comparison Between Diode Laser and Bleomycin in Treatment of Hemangioma
Assessment of the Effectiveness of Bleomycin Intralesional Injection and Diode Laser on Management of Infantile Hemangioma., with regard to : Clinically based on Change in the Size and Color of Hemangioma.
- Trial name
- NCT06510829
- Testing
- Diode laser
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Port Wine Stains
The Effects of Aldara as an Adjunct to Laser Treatment
The primary objective is to determine the effects of Aldara on the cosmetic outcome of laser treatment of vascular malformations.
- Trial name
- NCT00979550
- Testing
- Imiquimod, non-medicated petroleum cream
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Henry Vasconez
Hemangioma, Vascular Anomalies
Genetic Basis of Hemangiomas
The purpose of this study is to determine if there are genes that are common in children with infantile hemangioma. This information will allow physicians to improve care for patients who have been diagnosed with this disease and…
- Trial name
- NCT00466375
- Testing
- Cheek cell samples or blood sample (4mL), Cheek cell sample or blood sample (4mL)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Medical College of Wisconsin
LUMBAR Syndrome
Screening LUMBAR Syndrome in Infants With Infantile Hemangiomas
The objective of this study is to determine the maximal diameter threshold at which infants with lumbosacral, sacrococcygeal, perineal, gluteal, or lower-limb extending infantile hemangiomas should undergo screening for LUMBAR…
- Trial name
- NCT07616323
- Testing
- MRI
- Where
- China
- Volunteers
- 70 people
- Sponsor
- West China Hospital
Port-Wine Stain
Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain
This study is to provide safety information of hemoporfin during the post-marketing period as required by China Food and Drug Administration (CFDA) regulations in order to identify any potential drug related treatment factors in…
- Trial name
- NCT03181984
- Testing
- Hemoporfin
- Where
- 7 sites in China
- Volunteers
- 501 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Infantile Hemangioma
Nadolol Versus Propranolol in Children With Infantile Hemangiomas
The purpose of this study is to assess the efficacy and safety of oral propranolol versus nadolol in patients with Infantile Hemangiomas (IH) in a randomized, controlled, double-blinded study.
- Trial name
- NCT02505971
- Testing
- Nadolol, Propranolol
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- The Hospital for Sick Children
Hemangioma, Capillary
A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy
Hemangiomas of infancy, the most common benign tumors of infancy, are congenital or early infancy lesions characterized by a rapid postnatal growth, with high expression of angiogenic stimulators for 9-18 months, followed by slow…
- Trial name
- NCT00601016
- Testing
- Imiquimod 5% cream
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- St. Justine's Hospital
Infantile Hemangioma, Capillary Hemangioma
A Prospective Study on the Incidence and Related Risk Factors of Infantile Hemangioma in China
Infant hemangioma(IH) is the most common benign vascular tumor of infancy with the estimated incidence varies 1% to 12%.However, in China, the incidence of infant hemangioma and related epidemiological data remains unclear.
- Conditions
- Infantile Hemangioma, Capillary Hemangioma, Capillary Hemangiomas, Hemangioma, Capillary Infantile
- Trial name
- IH (NCT03173352)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Von Hippel Lindau, Von Hippel Lindau Disease
Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial
The BELIEVE-VHL Trial is a prospective real-life study designed to evaluate the therapeutic effects, benefits, and adverse effects of belzutifan, as well as the timing of treatment response and disease progression in patients…
- Conditions
- Von Hippel Lindau, Von Hippel Lindau Disease, Von Hippel Lindau-Deficient Clear Cell Renal Cell Carcinoma, Hemangioblastoma (HB) of the Central Nervous System (CNS)
- Trial name
- BELIEVE-VHL (NCT07167329)
- Testing
- Belzutifan
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- José Claudio Casali da Rocha
Port Wine Stain
A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
The researchers want to collect data on safety and efficacy of combined pulsed dye laser and rapamycin to improve fading/blanching of port wine stain birthmarks as compared to pulsed dye laser alone, which is the current standard…
- Trial name
- NCT00830466
- Testing
- Laser and rapamycin versus laser alone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Irvine
Port-Wine Stain
Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples
The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.
- Trial name
- NCT02051101
- Testing
- Biopsy sample from Port Wine Stain Birthmark
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Infantile Hemangioma (IH)
Abrupt Discontinuation Versus Gradual Tapering of Propranolol in Infantile Hemangioma
Infantile hemangioma is the most common benign vascular tumor in infancy. Oral propranolol is the first-line systemic treatment for infantile hemangiomas requiring therapy.
- Trial name
- PROIHSTOP (NCT07665177)
- Testing
- Abrupt Discontinuation of Propranolol, Gradual Tapering of Propranolol
- Where
- China
- Volunteers
- 110 people
- Sponsor
- West China Hospital
Infantile Hemangioma
Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas
Through this study, the investigators shall compare the effectiveness of atenolol with propranolol in the treatment of IH. In addition, the investigators shall try to elucidate the mechanism of action of beta blockers by…
- Trial name
- NCT03237637
- Testing
- oral propranolol, oral atenolol
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Port-wine Stain
A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine Stain
This pilot study aims to evaluate the safety and efficacy of hemoporfin photodynamic therapy (PDT) with different light doses for port-wine stain (PWS）in 2-7 years old children.
- Trial name
- NCT04106258
- Testing
- Hemoporfin PDT
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Port Wine Stain
Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks
The researcher want to improve port wine stain (PWS) therapeutic outcome in response to laser therapy. The researcher want to determine whether the combined use of pulsed dye laser (PDL) therapy and topical tacrolimus or…
- Trial name
- NCT00969397
- Testing
- Topical Antiangiogenic, Pulsed Dye Laser
- Sponsor
- University of California, Irvine
Infantile Hemangioma
''Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
''Evaluation of the Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
- Trial name
- NCT04684667
- Testing
- Propranolol Therapy for Infantile Hemangioma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Port Wine Stains
Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths
Port wine stain are a congenital, progressive vascular malformation of human skin. The pulsed dye laser is approved by the Food and Drug Administration for the treatment of choice.
- Trial name
- NCT00573729
- Testing
- Pulsed Dye Laser 577 nm, Pulsed Dye Laser 595 nm
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of California, Irvine
Hemangioma Skin
Topical Simvastatin for Treating Infantile Hemangioma
This is a 48-week, open-label pilot study to evaluate the safety, including systemic exposure and skin tolerability, and preliminary efficacy of 5% simvastatin ointment in the treatment of 15 children with newly diagnosed…
- Trial name
- TSTIH (NCT06273111)
- Testing
- 5% simvastatin ointment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Joyce Teng
Hemangioma
A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma.
- Trial name
- NCT01873131
- Testing
- topical timolol maleate, Pulsed dye laser
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Port Wine Stains
Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains
The goal of this clinical trial is to learn if the use of rapamycin cream can be used as a treatment together with pulsed dyed laser in treating port wine stain birthmarks.
- Trial name
- NCT07436611
- Testing
- Rapamycin cream, Pulsed dyed laser
- Where
- 2 sites in United States, Spain
- Volunteers
- 30 people
- Sponsor
- AFT Pharmaceuticals, Ltd.