Clinical trials: Hemodynamic
Sedation, Preoperative Anxiety Experienced by the Pediatric Patient
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population.
- Conditions
- Sedation, Preoperative Anxiety Experienced by the Pediatric Patient, Anxiolytic Effect, Sedation and Analgesia
- Trial name
- DREAM-Kids (NCT07180095)
- Testing
- Intranasal dexmedetomidine, Intranasal ketamine
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Traumatic Blunt Chest and/or Blunt Abdominal Injury
Hemodynamic and Ventilatory Responses to Head-down Postural Drainage Position
The purpose of this study is to explore acute hemodynamic and ventilatory responses to head-down 30 degree postural drainage position in patients with blunt chest and/or abdominal injury in the traumatic intensive care unit.
- Trial name
- NCT01668875
- Testing
- Head down 30 degree postural drainage position, Horizontal supine lying
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Plasma Volume, Tidal Volume
Effect of Tidal Volume Change on Pressure-based Prediction of Fluid Responsiveness in Children
This study evaluates predictability of fluid responsiveness of pressure-based dynamic variables such as pulse pressure variation and systolic pressure variation, according to tidal volume change in patients undergoing cardiac…
- Trial name
- NCT03963089
- Testing
- Tidal volume_6mL/kg, Tidal volume_10mL/kg, Tidal volume_14mL/kg
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus, Type 1, Nephropathy
Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function
Over 1.25 million Americans have type 1 diabetes (T1D), increasing risk for early death from cardiorenal disease. The strongest risk factor for cardiovascular disease (CVD) and mortality in T1D is diabetic kidney disease (DKD).
- Conditions
- Diabetes Mellitus, Type 1, Nephropathy, Diabetic Nephropathies, Juvenile Diabetes
- Trial name
- CASPER (NCT03618420)
- Testing
- Aminohippurate Sodium Inj 20%, Iohexol Inj 300 mg/mL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Patent Ductus Arteriosus in Preterm Infants
Noninvasive Hemodynamics Assessment of Preterms With Successful Medical Closure of PDA
The aim of our study was to use Electrical Cardiometry EC to monitor hemodynamic alternations during pharmacological closure of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm neonates
- Trial name
- NCT06606015
- Testing
- I.V Paracetamol., Echocardiography., Electrical Cardiometry
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Tanta University
Hemodynamic Instability
Hemodynamic Optimalization in Pediatric Patients
Hemodynamic unstability, defined by macrocirculation and/or microcirculation dysfunction or alteration is common in critically ill pediatric patients.
- Trial name
- HOPED (NCT04227821)
- Testing
- Vasopressor and/inotrope therapy
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Treatment Outcome by Stent-assisted Embolization
Safety and Efficacy of Stent Deployment for Intracranial Aneurysms (SESIA)
Intracranial aneurysms (IA) regarded the third cause of cerebral vascular disease is the majoy cause of subarachnoid hemorrhage (SAH). The mortality and morbidity account for 22% to 25% in cerebrovascular disease.
- Trial name
- SESIA (NCT03387995)
- Testing
- LVIS stent, Solitaire stent, Enterprise stent
- Where
- China
- Volunteers
- 4,157 people
- Sponsor
- Zhujiang Hospital
Dental Anesthesia, Nasal Surgical Procedures
Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
Oxymetazoline is an α-adrenergic agonist that is commonly used as a topical sympathomimetic agent in over-the-counter decongestant sprays.
- Conditions
- Dental Anesthesia, Nasal Surgical Procedures, Intranasal Drug Administration
- Trial name
- NCT02062996
- Testing
- Oxymetazoline
- Where
- United States
- Sponsor
- Richard Cartabuke
Heart Rate, Blood Pressure
Effect of Local Anesthetic on Hemodynamic Measures During Nasal Surgery
1% Lidocaine with 1:100,000 to 1:200,000 of epinephrine is routinely injected into the nasal mucosa during nasal surgery to reduce patient blood loss and improve the surgical field and visibility.
- Conditions
- Heart Rate, Blood Pressure, Blood Loss During Surgery, Surgical Field
- Trial name
- NCT01701960
- Where
- United States
- Sponsor
- Loma Linda University
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
This study evaluates the effects of bosentan on oxygen saturation, hemodynamics and exercise capacity in patients with pulmonary arterial hypertension related to Eisenmenger physiology.
- Trial name
- NCT00317486
- Testing
- bosentan
- Volunteers
- 54 people
- Sponsor
- Actelion
Patient Cataract
Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation
we use two different technique of anaesthesia for anaesthesia of patient undergoining CPC operation (20 each) were comparable with regard to demographic data and hemodynamic variables, IOP.
- Trial name
- cyclophotocoag (NCT07445672)
- Testing
- Propofol and Fentanyl administration, Sevoflurane and fentanyl administration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Iron Deficiency Anemia
Fetal Vascular Hemodynamic Changes in Iron Deficiency Anemia
Iron deficiency anemia is a worldwide medical disorder. So far, it is the most common medical complication in pregnancy specially in developing countries.
- Trial name
- NCT03883841
- Testing
- Iron Sucrose Solution for Injection
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hemodynamic Monitoring
Effect of Cardiorespiratory Changes on Carotid Flow Time During Lung Resection Surgery
Cardiorespiratory changes during lung resection surgery, even though generally well tolerated, may lead to hemodynamic compromise, reducing venous return to the heart and hence cardiac output.
- Trial name
- NCT07808749
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Fontan Physiology
Effects of Different Tidal Volume Ventilation Strategies on Fontan Flow and Hemodynamics
In patients with Fontan circulation blood is not pumped to the lungs from a ventricle. Instead the superior vena cava and inferior vena cava is connected to the pulmonary artery and blood flow to the lungs occurs passively along…
- Trial name
- NCT04633343
- Testing
- Small volume breath and fast breathing rate for 5 minutes, Large volume breath and slow breathing rate for 5 minutes
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Epilepsy
Electro- Hemodynamic Activity in Children: Combined Analysis by Video -EEG Spectroscopy and Near-infrared (NIRS )
Epilepsy in children is a major public health issue. It is the first neurological disease of the child.
- Trial name
- AEHCEE (NCT02826915)
- Testing
- Near Infra Red Spectroscopy (NIRS), Electroencephalogram (EEG)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bronchopulmonary Dysplasia
The Impact of Lung Recruitment Maneuver in 24-32 Weekers, and the Incidence of Bronchopulmonary Dysplasia
hypothesis : 1. The incident of dysplasia bronchopulmonary and/or death in 24-32 weekers babies on assist-control volume guarantee ventilation are lower in lung recruitment maneuver (LRM) group compare to control. 2.
- Trial name
- NCT04555889
- Testing
- lung recruitment maneuver (LRM) with DrageerVN500
- Volunteers
- 110 people
- Sponsor
- Dr. R. Adhi Teguh Perma Iskandar, Sp.A(K)
Transgenderism, Kidney Diseases
Effect of Hormone Therapy on Renal Function
The purpose of this study is to understand the effects of testosterone or estradiol on kidney function in transgender adolescents and young adults.
- Conditions
- Transgenderism, Kidney Diseases, Kidney Injury
- Trial name
- NCT04482920
- Testing
- p-aminohippurate clearance study, Iohexol infusion
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
Atrial Fibrillation
The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation
The purpose of this study is to 1) assess the effect of routine exercise on the quality of life of patients with permanent atrial fibrillation, and 2) assess the effect of exercise on cardio-hemodynamics in patients with atrial…
- Trial name
- NCT00680290
- Testing
- Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center