Clinical trials: High Altitude
High Altitude Pulmonary Hypertension
Right Ventricular Function During Exercise in Highlanders/Lowlanders
The purpose of the current study is to evaluate the right ventricular function during graded cycling on an ergometer by transthoracic echocardiography in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by…
- Trial name
- NCT03165032
- Where
- Kyrgyzstan
- Volunteers
- 173 people
- Sponsor
- University of Zurich
Surfactant
Surfactant for Neonatal Respiratory Distress Syndrome at High Altitude Areas:a Prospective Cohort Study
The traditional concept believes that the etiology of neonatal respiratory distress syndrome (RDS) is immature development of lung,especially the surfactant synthesis system,and RDS is still one of the major causes of mortality…
- Trial name
- NCT03479450
- Testing
- surfactant
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Critical Congenital Heart Disease, High Altitude
Oxygen Saturation and Perfusion Index ın Neonates at High Altitude
Congenital heart diseases are among the most common congenital anomalies and occur with an incidence of approximately 8ınd12 / 1,000 live births worldwide.
- Trial name
- NCT04290481
- Testing
- oxygen saturation and perfusion index screening
- Where
- Turkey (Türkiye)
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Ataturk University
NRDS, Surfactant
Pulmonary Surfactant(PS) Therapy at High Altitude Area
The traditional concept believes that the etiology of neonatal respiratory distress syndrome (RDS) is immature development of lung,especially the surfactant synthesis system,and RDS is still one of the major causes of mortality…
- Trial name
- NCT03440333
- Testing
- surfactant
- Volunteers
- 400 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Hematopoietic Stem Cell Transplantation (HSCT), Acute Myeloid Leukemia (AML)
High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)
The High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT) study is the first prospective real-world cohort of hematologic diseases and transplantation in the Qinghai-Tibet Plateau.
- Conditions
- Hematopoietic Stem Cell Transplantation (HSCT), Acute Myeloid Leukemia (AML), Leukemias, Acute Myeloid, Myeloid Leukemias, Acute
- Trial name
- HALO-SCT (NCT07205523)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Yigeng Cao,MD,PhD
Gastrointestinal Injury, Acute Mountain Sickness
Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude
The aim of this randomized, crossover clinical trial is to determine the efficacy of a gut microbiota-targeted nutritional intervention containing a blend of fermentable fibers and polyphenols (FP) for mitigating increases in GI…
- Trial name
- NCT04111263
- Testing
- FP, High altitude, Sea level
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
High Altitude
Establishing the Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitude
The now widely used reference interval for pulse oxygen saturation of the neonate after 24 hours of birth has been developed relying on data from low altitude.It is not suitable for neonates at high altitude.
- Trial name
- NCT05115721
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Gastric Perforation
High Altitude Area- A Risk Factor For Gastric Perforation?
This is an original case series on soldiers evacuated from HAA(High Altitude Area) over last one year(Sept 2017- Aug 2018) , of which 100% cases were found to have gastric antrum perforation.
- Trial name
- NCT03724513
- Where
- India
- Volunteers
- 5 people
- Sponsor
- ADITYA PAWAR
High-altitude Training Adaptations in Adolescent Male Rowers
Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers
This study aims to investigate the effects of a 4-week altitude training program on adolescent male rowers. The research will examine changes in athletic performance, athletic body composition, athletic cardiac function, athletic…
- Trial name
- NCT07612956
- Testing
- 4-Week Altitude Training
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
High Altitude Pulmonary Edema, Acute Mountain Sickness
Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness
The purpose of this study is to determine whether regular oral use of sildenafil citrate can prevent or attenuate high altitude illnesses.
- Trial name
- NCT00627965
- Testing
- Sildenafil citrate
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Altitude Physiology Expeditions
Adolescent Swimmers
Effects of Six Weeks of Sub-High-Altitude Training on the Physical Performance and Psychological State of Adolescent Swimmers
To investigate the effects of sub-altitude training on the physical performance and psychological state of adolescent swimmers and to analyze the possible mechanisms underlying these effects
- Trial name
- NCT07786935
- Testing
- sub-altitude training
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xiang Gao
Periampullary Cancer
Clinical Impact of Altitude Level on Surgical Outcomes of Pancreaticoduodenectomy
Very few papers examine the effect of living at high altitudes on surgical results of major operations. This research is designed to determine the surgical outcomes of PD for periampullary tumour in high altitudes and normal…
- Trial name
- PD (NCT04401722)
- Testing
- PANCREATICODUDENECTOMY
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
High Altitude Pulmonary Hypertension
Cerebral Tissue Oxygenation in Highlanders/Lowlanders
The purpose of the current study is to evaluate the cerebral tissue oxygenation of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study.
- Trial name
- NCT03172429
- Where
- Kyrgyzstan
- Volunteers
- 79 people
- Sponsor
- University of Zurich
High Altitude Pulmonary Hypertension, Sleep Apnea
Time Course and Prognostic Significance of Pulmonary Artery Pressure in Highlanders.
The purpose of the current study is to evaluate the clinical and physiologic course of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study.
- Trial name
- NCT03165019
- Where
- Kyrgyzstan
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sleep Disorder; Breathing-Related
WatchPAT Compared to PSG at 8500'
Subjects who consent to participate in the research will undergo a simultaneous recording of inlab PSG and WatchPAT200 for comparing the WatchPAT data to PSG at an altitude of 8500'.
- Trial name
- NCT04249011
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Itamar-Medical, Israel
High Altitude Pulmonary Hypertension
Right Ventricular Function at Rest in Highlanders/Lowlanders
The purpose of the current study is to evaluate the progression of right ventricular function and dimension in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a cross sectional case-control study.
- Trial name
- NCT03165656
- Where
- Kyrgyzstan
- Volunteers
- 173 people
- Sponsor
- University of Zurich
Altitude, Ultraviolet Rays
Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude
With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses.
- Conditions
- Altitude, Ultraviolet Rays, Antioxidants, Oxidative Stress
- Trial name
- NCT00685438
- Where
- Nepal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Neuromuscular Diseases, High Altitude Hypoxia
Assessing Air Travel Safety in Neuromuscular Dystrophy: Standard Versus Prolonged High Altitude Simulation Tests
To determine if a prolonged high altitude simulation test (HAST) lasting two hours, identifies more patients at risk of respiratory failure than the standard HAST lasting 20 minutes, in patients with neuromuscular disease (NMD)…
- Trial name
- NCT03312361
- Testing
- 15% oxygen
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- The Hospital for Sick Children
Neonatal Disease, Altitude Hypoxia
Reference Interval for SPO2 in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas
Pulse oximetry offers real time and non-invasive estimation of arterial oxygen saturation in a cost-effective way, and has become a critical tool in guiding the usage of supplemental oxygen in sick newborns.
- Trial name
- NCT05468515
- Testing
- pulse oxygen saturation
- Where
- China
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Emotions
The Impact of a 3-day High-altitude Mountain Trek on the Emotional States of Children
The mood was influenced by many factors in children. Sport, such as high-altitude mountain trek activity was thought benefit for human's mood and health. The expedition therapy was more and more popular in many schools recently.
- Trial name
- NCT02830711
- Testing
- Positive and Negative Affect Scale for Children
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital