Clinical trials: Hope
Recurrent Childhood Medulloblastoma, Recurrent Ependymoma
Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors
This phase I trial studies the side effects and best dose of expanded natural killer cells in treating younger patients with brain tumors that have come back or do not respond to treatment.
- Conditions
- Recurrent Childhood Medulloblastoma, Recurrent Ependymoma, Recurrent Medulloblastoma
- Trial name
- NCT02271711
- Testing
- Laboratory Biomarker Analysis, Natural Killer Cell Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- M.D. Anderson Cancer Center
End Stage Liver DIsease, Liver Failure
VitaSmart HOPE System: Bridge to HOPE Registry
This is a post-market, multicenter, single-arm, observational registry evaluating real-world use of the VitaSmart HOPE System under standard of care conditions.
- Trial name
- NCT07578441
- Testing
- hypothermic oxygenated perfusion therapy of a donor liver under standard of care conditions
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Bridge to Life Ltd.
Craniofacial Differences
Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences
This study will describe the use of an intervention, developed by an organization called Positive Exposure, to improve self-perceptions among adolescents and young adults who may encounter the stigma, or negative effect, of…
- Trial name
- NCT00340964
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Laughter Therapy, Laughter Yoga
The Effect of Laughter Yoga on Hope and School Burnout
This study aimed to evaluate the effect of laughter yoga on hope and school burnout among secondary school (8th Grade) students.
- Conditions
- Laughter Therapy, Laughter Yoga, Hope, School Burnout
- Trial name
- NCT05742308
- Testing
- Laughter yoga
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Malnutrition, Child
Hens Hatching Hope
The study is a prospective community-cluster non-randomized trial that will evaluate the effectiveness of a program that will provide 30-day egg vouchers to mothers of 6 to 24 month-old children living in rural areas of Intibucá…
- Trial name
- NCT04721197
- Testing
- Egg vouchers, Standard of Care
- Where
- Honduras
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Severe Mental Disorder, Severe Mental Illness
"Pilot Study of Music Intervention for Recovery of People With Severe Mental Disorder in the Community"
The aim of this study was to analyze the effect of music therapy on hope, quality of life, and social functioning in individuals with Severe Mental Disorder in the community.
- Trial name
- NCT07379996
- Testing
- Passive music therapy in an individual format
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Alejando Vargas Rubio
Heart Transplant Failure and Rejection, Coronary Artery Disease
Percutaneous Coronary Intervention in Patients witH OrthotoPic hEart Transplantation: the PCI-HOPE a Multicenter Study.
This is a retrospective, multicenter, study including patients undergone to one or more percutaneous revascularization after OHT.
- Trial name
- PCI-HOPE (NCT03538509)
- Testing
- PCI and implantation drug eluting stent or bare metal stent
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fabrizio D'Ascenzo
Pediatric Cancer
Narrative-based Card Game in Improving Spiritual Well-being Among Chinese Childhood Cancer Patients
Cancer as a life-threatening disease can trigger children's unique spiritual needs. Unmet spiritual needs can cause low level of spiritual well-being, which is a central component for the overall quality of life (QoL) of cancer…
- Trial name
- NCT05639062
- Testing
- Narrative-based card game
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Giant Axonal Neuropathy (GAN)
Intraneural Administration of scAAV9/JeT-GAN Into the Vagus Nerve for Patients With Giant Axonal Neuropathy (GAN)
Giant axonal neuropathy (GAN) is a rare pediatric disorder caused by autosomal recessive mutations in the GAN gene. GAN is a multisystem, neurodegenerative disorder affecting the peripheral nervous system (PNS), central nervous…
- Trial name
- NCT07543991
- Testing
- scAAV9/JeT-GAN
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Texas Southwestern Medical Center
Behavior Problem
Effectiveness of the MY LIFE Treatment for Adolescents With Behavioral Problems
Objective This study examines the effects of the MY LIFE treatment, a group intervention aiming to increase hope, self-worth and social support seeking in adolescents with behavioral problems in mental health care.
- Trial name
- NCT05581914
- Testing
- MY LIFE treatment, Care as Usual
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Pancreatic Cancer
Individual Patient Expanded Access IND of Hope Biosciences First Blood Relative Allogeneic Adipose-derived Mesenchymal Stem Cells (HB-adMSCs) for Pancreatic Cancer
The drug for this submission is Hope Biosciences' allogeneic, first blood relative, adipose-derived culture-expanded mesenchymal stem cells (HB-adMSCs) for the treatment of a single patient with Pancreatic Cancer (PC).
- Trial name
- NCT04087889
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences LLC
Mastectomy Related Lymphedema, Lymphedema of Upper Limb
Testing an Intervention to Foster Hope for Cancer Survivors With Lymphedema
The specific objectives and research questions of the proposed study are: 1. a. Administer a group rehabilitation intervention to address loss and foster hope in 30 participants with upper and lower limb SLC --15 in an…
- Conditions
- Mastectomy Related Lymphedema, Lymphedema of Upper Limb, Lymphedema of Lower Extremity
- Trial name
- NCT02453295
- Testing
- Intervention Group
- Volunteers
- 60 people
- Sponsor
- University of Ottawa
Cancer
Improving Health Behaviors for Pediatric Cancer Survivors
The objective of this study is to examine the efficacy of Harvesting Hope for Kids (HH4K), a biobehavioral intervention delivered in the context of a university-based, cancer survivor garden, to increase produce intake and…
- Trial name
- NCT04097353
- Testing
- Harvesting Hope for Kids (HH4K), Surviving Strong for Kids (SS4K)
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Cynthia Gerhardt
Pediatric Liver Transplantation
Hypothermic Oxygenated Machine PErfusion During Ex-vivo SPLITting in Liver Pediatric Transplantation (HOPESPLIT)
Ex-vivo split liver transplantation (SLT) has been developed to increase organ availability and offer a rapid access to transplantation for pediatric recipients.
- Trial name
- HOPE SPLIT (NCT07918183)
- Testing
- End-ischemic Hypothermic Oxygenated Machine Perfusion (HOPE), Classic static cold storage
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Suicidal Ideation
Circles of Hope: Group Intervention for Adolescents With Suicidal Symptoms
This pilot study examines the feasibility, acceptability, and preliminary outcomes of a short-term group psychotherapy intervention for adolescents experiencing suicidal symptoms without immediate suicidal intent.
- Trial name
- COH (NCT07818863)
- Testing
- Circles of Hope Group Psychotherapy
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Stress
Impact of a Financial Success Education Program in Women and Children
Many Americans are living paycheck to paycheck. This may lead to financial stress and an increase in overall stress. People under stress are more likely to smoke, consume alcohol, eat a poor diet, and experience depression or…
- Trial name
- NCT01409291
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Creighton University
Premature Birth
Feeding and Transition to Home for Preterms at Social Risk
Premature infants are at high risk of suboptimal health and development. This randomized clinical trial evaluated the impact of a developmentally based intervention, H-HOPE (Hospital-home transition: optimizing prematures'…
- Trial name
- H-HOPE (NCT02041923)
- Testing
- H-HOPE, Attention Control
- Where
- 2 sites in United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Hand-washing Behavior, Diarrhea
The Hope Soap Study: a Hand-washing Intervention Among Children in South Africa
The Hope Soap Study is a randomised-control pilot study of a hand-washing intervention in which children in treatment households received a bi-monthly delivery of HOPE SOAP©, a colourful, translucent bar of soap with a toy…
- Trial name
- NCT03280771
- Testing
- Hope Soap, Control group soap
- Volunteers
- 288 people
- Sponsor
- University of Cape Town
Children With Cancer
Four Life Domains Vision Board Program
This randomized controlled trial aims to evaluate the effect of a Four Life Domains-Based Vision Board Program on hope and psychological resilience among adolescents undergoing cancer treatment.
- Trial name
- NCT07367048
- Testing
- Four Life Domains Vision Board Program
- Volunteers
- 60 people
- Sponsor
- Gazi University
Anxiety
A Mind-Body Medicine Curriculum for Peer Counselors
This study will evaluate a Mind-Body Medicine curriculum for high school peer counselors in order to answer the following research questions: 1.
- Trial name
- NCT03718845
- Testing
- Mind-Body Medicine Curriculum
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine