Clinical trials: Hospitalized
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19)
A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19
A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People with Weakened Immune Systems or at Increased Risk for Poor Outcomes who are Hospitalized Due to Severe COVID-19
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19), Immunocompromised, Hospitalization
- Trial name
- EPIC-HOS (NCT05545319)
- Testing
- Nirmatrelvir, Ritonavir
- Where
- 11 sites in United States, Bulgaria
- Sponsor
- Pfizer
Hospitalized Patients
Appropriate Evaluation of Antiviral Therapy With Nirmatrelvir-ritonavir in Hospitalized Patients
The primary objective of the study was to assess the appropriateness of antiviral therapy with nirmatrelvir-ritonavir in hospitalized patients.
- Trial name
- NCT05749445
- Testing
- Nirmatrelvir-Ritonavir
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital of Hangzhou
Children,Hospitalized, Vascular Access Devices
Implementation and Evaluation of the Selection Scheme of Peripheral Venous Infusion Devices for Hospitalized Children
This study is a stepped wedge cluster randomized trial design. The object is to evaluate the influence on patient outcomes, medical staff's evidence-based practice behavior and hospital context after implementation of the…
- Trial name
- NCT05378568
- Testing
- the selection scheme of peripheral venous access devices, the existing nursing routine
- Where
- China
- Volunteers
- 4,652 people
- Sponsor
- Children's Hospital of Fudan University
Hospitalized Children With Suspected or Confirmed Nosocomial Pneumonia
Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia
This is a multicenter, multinational, open label single dose pharmacokinetic (PK) study enrolling at least 32 subjects. The study aims to characterize the pharmacokinetics (PK) of a single intravenous dose of CAZ AVI in pediatric…
- Trial name
- NCT04040621
- Testing
- Ceftazidime-avibactam
- Where
- 4 sites in China, Taiwan
- Volunteers
- 4 people
- Sponsor
- Pfizer
Hospitalized Neonates and Infants, Expected to Require Parenteral Nutrition for 28 Days
Phase 3 Study to Compare Safety and Efficacy of Smoflipid 20% to Intralipid 20% in Hospitalized Neonates and Infants
To show the superiority in safety of Smoflipid over Intralipid® as measured by the number of study patients in each treatment group with conjugated bilirubin exceeding 2 mg/dL during the first 28 days of study treatment…
- Trial name
- NCT02579265
- Testing
- Smoflipid 20% (investigational lipid for parenteral nutrition), Intralipid® 20%
- Where
- 13 sites in United States
- Volunteers
- 204 people
- Sponsor
- Fresenius Kabi
Hospitalized Children, Covid-19 Infection
Efficacy of Human Coronavirus-immune Convalescent Plasma for the Treatment of COVID-19 Disease in Hospitalized Children
This is a multicentered, open-label, randomized controlled Phase 2 trial to evaluate the safety and efficacy of providing human coronavirus-immune convalescent plasma as treatment for COVID-19 disease in hospitalized children in…
- Trial name
- CONCOR-KIDS (NCT04377568)
- Testing
- Convalescent plasma (CP)
- Where
- 13 sites in Canada
- Sponsor
- The Hospital for Sick Children
Blood Disease, Cancer
Medical Clowning: Needs Assessment and Implication for Hospitalized Children With Cancer/Blood Disease
Hospitalized children who undergo painful procedures are more susceptible than others to experiencing iatrogenic effects, such as anxiety, pain, and severe stress.
- Conditions
- Blood Disease, Cancer, Friendly Healthcare in Children, Medical Clown
- Trial name
- NCT03586180
- Testing
- Medical Clowning for children
- Where
- Taiwan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hospitalized Patients With Covid-19 Pneumonia
Use of Ascorbic Acid in Patients With COVID 19
Different studies showed that ascorbic acid (vitaminC) positively affects the development and maturation of T-lymphocytes, in particular NK (natural Killer) cells involved in the immune response to viral agents.
- Trial name
- NCT04323514
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Child, Hospitalized, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Improvement of Pneumonic Children
In Egypt, according to UNICEF 2018, Acute Respiratory Tract Infection (ARTIs)was estimated to account for 11% and 19% of the under-five and post-neonatal mortalities respectively.
- Conditions
- Child, Hospitalized, Vitamin D Deficiency, Pneumonia
- Trial name
- NCT04244474
- Testing
- A single one ml injection
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Cairo University
Breastfeeding Mothers of Infants Hospitalized
The "Pooling" Expressed Breast Milk: A Method for Improving the Nutritional Intake of Premature Infants
The investigators compared a pooled mother's expressed breastmilk for 24 hours with individual pump session collection of milk to provide a more consistent caloric product without increasing bacterial contamination.
- Trial name
- POOL-BM (NCT02994823)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hospitalized Child
Effect of Augmented Reality Books on Cortisol Levels in Hospitalized Pediatric Patients
Hospitalization is a stressful event that might impact in a patient's recovery. Children are more susceptible to suffer acute stress as a result of a hospital stay.
- Trial name
- NCT03537859
- Testing
- Augmented Reality, Non Augmented Reality
- Where
- Peru
- Volunteers
- 29 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Focus: Hospitalized Patients
Hospital to Home Outcomes
Home Nurse Visit post discharge.
- Trial name
- NCT02081846
- Testing
- Nurse Home Visit, Standard of Care
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hospitalized Patients
Supplement to Hospital to Home Outcomes
Post-discharge nurse phone call
- Trial name
- Supplement (NCT03224130)
- Testing
- Nurse Phone Call, Standard of Care
- Where
- United States
- Volunteers
- 966 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Child, Hospitalized, Delivery of Health Care
Family-Centered Rounds Checklist Implementation
The goal of this study is to develop, implement, and evaluate the effectiveness of an intervention designed to facilitate family engagement during bedside rounds at a children's hospital.
- Conditions
- Child, Hospitalized, Delivery of Health Care, Morning Rounds
- Trial name
- NCT02625142
- Testing
- Family-centered rounds checklist tool
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neonates or Premature Babies, Patient With Urinary Catheter
Exposure of NICU Patients to PVC Plasticizers in At-risk Clinical Situation: Biomonitoring Study From Urinary Samples
In response to restrictions related to the use of DEHP as a plasticizer for PVC medical devices (MDs), manufacturers have resorted to alternative plasticizers.
- Conditions
- Neonates or Premature Babies, Patient With Urinary Catheter, Patient Hospitalized in NICU
- Trial name
- ARMED NEO (NCT03477409)
- Testing
- plasticizers
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain Measurement, Children
Pain Management in Pediatric Intensive Care by Studying the Autonomic Balance
Fighting against the pain caused by the disease or by the diagnostic and therapeutic procedures for children is a daily and essential concern of health care in the pediatric sector.
- Conditions
- Pain Measurement, Children, Child, Hospitalized
- Trial name
- ANI-DOL (NCT02769598)
- Testing
- ANI Index for Hospitalized children
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Teenager, Young Adult
Cognitive Remediation Therapy in Anorexia Nervosa
"Clinicians from the Maudsley (IoP, London, UK) have specifically tailored a cognitive remediation therapy (CRT) for treating Anorexia Nervosa (AN).
- Conditions
- Teenager, Young Adult, Hospitalized, Anorexia Nervosa (DSM-IV Revised Criteria)
- Trial name
- TreCogAM (NCT01772394)
- Testing
- Cognitive Remediation Therapy
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hospitalized Cases of Angioneurotic Oedema, Pneumonia
Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
The purpose of this study is 1. To describe patient characteristics and drug usage among children that are prescribed esomeprazole for the first time and to compare them with patients who are prescribed other proton pump…
- Conditions
- Hospitalized Cases of Angioneurotic Oedema, Pneumonia, Gastroenteritis, Failure to Thrive
- Trial name
- NCT01338363
- Where
- Netherlands
- Volunteers
- 23,470 people
- Sponsor
- AstraZeneca
Hospitalized Children
Relationship Between Adverse Drug Reactions and Unlicensed/ Off-label Drug Use in Hospitalized Children
Medications are the most commonly used clinical intervention and complications associated with their use are one of the most common causes of adverse events in health care.
- Trial name
- EREMI (NCT02852590)
- Where
- France
- Volunteers
- 6,227 people
- Sponsor
- Hospices Civils de Lyon
All Hospitalized Patients, With and Without Catheter
Effectiveness of Catheter Reminder and Evaluation Program
The investigators will conduct a cluster randomized controlled trial to evaluate the efficacy of Catheter Reminder and Evaluation program (CARE) in reducing the duration of catheter use and the number of infection relating to…
- Trial name
- CARE (NCT01797146)
- Testing
- Catheter Reminder and Evaluation Program
- Where
- Thailand
- Volunteers
- 874 people
- Sponsor
- Siriraj Hospital