Clinical trials: Hospitalized
Covid19, Respiratory Disease
Post COVID19 Functional and Cognitive Assessments
The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment.
- Conditions
- Covid19, Respiratory Disease, Walking, Difficulty, Cognitive Decline
- Trial name
- PostCovidZRS (NCT04860206)
- Where
- Slovenia
- Volunteers
- 43 people
- Sponsor
- Science and Research Centre Koper
Covid19, Venous Thromboembolism
Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial
The Michelle trial is expected to provide high-quality evidence around the role of extended thromboprophylaxis in COVID-19 and will help guide medical decisions in clinical practice.
- Trial name
- MICHELLE (NCT04662684)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Science Valley Research Institute
Severe Acute Respiratory Infection
Clinical Trial to Assess the Influenza Vaccination of the Hospitalized Adults
This study assesses the seasonal of influenza vaccine effectiveness in adults hospitalised with laboratory-confirmed influenza through a network of hospitals in France.
- Trial name
- FLUVAC EV-03 (NCT02027233)
- Testing
- nasopharyngeal sample
- Where
- France
- Volunteers
- 6,173 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
COVID-19
Low-dose Tocilizumab Versus Standard of Care in Hospitalized Patients With COVID-19
Tocilizumab is an effective treatment for severe coronavirus disease 2019 (Covid-19) pneumonia and related inflammation. Given limited global supplies, clarification of the optimal tocilizumab dose is critical.
- Trial name
- COVIDOSE-2 (NCT04479358)
- Testing
- Tocilizumab, Standard of Care
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Chicago
Breastfeeding
Using Mother's Raw Milk Could Improve Breastfeeding in Hospitalized Neonates
Despite the importance of breast milk for sick or preterm neonates, there is currently no consensus regarding the use of raw mother's own milk (MOM) in neonatal units.
- Trial name
- DOAL (NCT02819193)
- Testing
- raw mother's own milk
- Where
- France
- Volunteers
- 665 people
- Sponsor
- Hospices Civils de Lyon
Bronchiolitis
Oxygen Saturation Monitoring in Bronchiolitis
The investigators will conduct a study around the best way to monitor infants hospitalized with bronchiolitis, the most common lung infection and a leading reason for hospitalization in infants.
- Trial name
- NCT02947204
- Testing
- Intermittent oxygen monitoring, Continuous oxygen monitoring
- Where
- 6 sites in Canada
- Volunteers
- 219 people
- Sponsor
- The Hospital for Sick Children
COVID19, Intensive Care Unit
Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, Associated With Standards Treatments in COVID-19 (+) Patients Hospitalized In Intensive Care in Tunisia
Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, associated with standards treatments in COVID-19 (+) patients, Hospitalized In Intensive care in Tunisia. Multicentric, comparative, randomized study.
- Trial name
- TRONCHER (NCT04361032)
- Testing
- Tocilizumab Injection, Deferoxamine
- Where
- Tunisia
- Volunteers
- 260 people
- Sponsor
- Abderrahmane Mami Hospital
Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic)
Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia
The study compares two current practices for calculating insulin dose for admitted patients: flexible fixed mealtime dosing based on percent of meal eaten and carbohydrate counting based on amount of carbohydrates eaten.
- Conditions
- Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic), Hyperglycemia Due to Type 2 Diabetes Mellitus
- Trial name
- MEND (NCT07808398)
- Testing
- Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Pneumonia, Severe Acute Respiratory Syndrome
Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19
This phase III trial compares low dose whole lung radiation therapy to best supportive care plus physicians choice in treating patients with COVID-19 infection.
- Conditions
- Pneumonia, Severe Acute Respiratory Syndrome, Symptomatic COVID-19 Infection Laboratory-Confirmed
- Trial name
- RESCUE1-19 (NCT04433949)
- Testing
- Best Practice, Low Dose Radiation Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Bipolar Disorder, Suicide
MAPS Group Therapy Model for Bipolar Disorder
This study aims to develop the MAPS(M,Monitoring;A,Assessing;P,Preventing or Reducing Relapse;S,Smart goal setting) group therapy model for bipolar disorder patients as other adjuvant clinical treatment and develop the…
- Trial name
- NCT01152034
- Testing
- psychoeducation group therapy
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Mackay Memorial Hospital
Eating Disorders
Developing Recommendations to Support Therapeutic Alliance in Eating Disorders Inpatient Treatment
The ALLIANCE study aims to understand and improve treatment relationships between staff and service users in inpatient eating disorder settings.
- Trial name
- ALLIANCE (NCT06961032)
- Where
- 3 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
COVID-19
Interferon Beta 1a in Hospitalized COVID-19 Patients
The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical…
- Trial name
- IB1aIC (NCT04350671)
- Testing
- Interferon Beta-1A, Lopinavir / Ritonavir, Single Dose of Hydroxychloroquine
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
COVID19, Ophthalmopathy
Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic
Ophthalmologic damages secondary to COVID-19 coronavirus infection are little described. The ocular involvement is probably multiple, ranging from pathologies of the anterior segment such as conjunctivitis and anterior uveitis to…
- Trial name
- SOCOVID (NCT04387292)
- Testing
- Ophthalmologic exam
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Patients Hospitalized in a FRC Department
Validation of a SOFMER Activity Scale
A person's dependency is defined as the total or partial inability to perform without helps the necessary activities of daily life due to activity limitations in the usual environment.
- Trial name
- SAS (NCT03116204)
- Testing
- Assessment of score SAS
- Where
- 9 sites in France
- Volunteers
- 152 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
Safety and Efficacy of Tofacitinib in Hospitalized Participants With COVID-19 Pneumonia Who Are Receiving Standard of Care Therapy
The study is designed as a multicenter, randomized, double-blind, placebo-controlled, parallel group study of the safety and efficacy of tofacitinib in hospitalized adult participants with COVID-19 pneumonia who are receiving SoC…
- Trial name
- NCT04412252
- Testing
- Tofacitinib
- Where
- 6 sites in United States
- Sponsor
- Pfizer
Social Needs, Health-Related Social Needs
The Social Needs Assistance for Hospitalized Kids Trial
The goal of this clinical trial is to determine the best way to help families access social and economic support services in order to improve children's health for hospitalized children and their families/caregivers.
- Conditions
- Social Needs, Health-Related Social Needs, Social Determinants of Health (SDOH), Social Needs Status
- Trial name
- SNAK (NCT07687238)
- Testing
- Active Assistance by Navigators, Passive Referral
- Where
- 6 sites in United States
- Volunteers
- 1,880 people
- Sponsor
- University of California, San Francisco
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Liver Cirrhosis, Acute Kidney Injury
International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project
The aims of this study will be to identify the clinical characteristics, the management and the outcomes of acute kidney injury in patients with cirrhosis worldwide. Specific aims: 1.
- Conditions
- Liver Cirrhosis, Acute Kidney Injury, Hepatorenal Syndrome
- Trial name
- GLOBAL-AKI (NCT05387811)
- Testing
- Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy
- Where
- 38 sites in United States, Argentina and 19 more
- Volunteers
- 1,456 people
- Sponsor
- Azienda Ospedaliera di Padova
Schizophrenia
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia
The primary objective for this study is to evaluate the efficacy of NBI-1117570 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults who warrant inpatient hospitalization.
- Trial name
- NCT07288333
- Testing
- NBI-1117570
- Where
- 6 sites in Bulgaria, Romania and 1 more
- Volunteers
- 120 people
- Sponsor
- Neurocrine Biosciences
Hematologic Diseases
The Impact of the Practice of Touch-massage on the Anxiety of Patients With Hematological Disorders Hospitalized in a Protective Environment, a Randomized, Controlled Study
Each year, 17000 cases of severe hematological diseases are diagnosed in France, with more than 6,000 of these requiring hospitalization in a protective, sterile environment.
- Trial name
- TANDHEMS (NCT02343965)
- Testing
- Touch-massage
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Nantes University Hospital
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