Clinical trials: Hyperkeratosis
Nevus, Seborrheic Keratosis (SK)
Impact of Skin Type on Wonud Healing and Scarring Following Facial Skin Surgery
The goal of this observational study is to learn how an individual's skin type influences the wound healing process and scar formation in Chinese patients undergoing facial dermatologic surgery.
- Conditions
- Nevus, Seborrheic Keratosis (SK), Cyst, Lipoma
- Trial name
- NCT07384299
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Cholesteatoma
Magnetic Resonance (MR) Imaging in the Post Operative Follow-up of Cholesteatoma in Children
Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the…
- Trial name
- NCT00682409
- Testing
- MR Imaging
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cholesteatoma, Middle Ear, Cholesteatoma, Residual
Comparison of Outcomes of Microscopic Mastoidectomy With and Without Check Endoscopy
Cholesteatoma is a serious otological condition and a major challenge for otolaryngologists worldwide. If left undetected and untreated, it can erode the surrounding bone, ear ossicles, facial nerve canal, bony labyrinth or…
- Trial name
- NCT07896200
- Testing
- Microscopic Mastoidectomy, Check Endoscopy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Zinc Absorption, Iron Absorption
Guatemala Biofortified Maize Study
Zinc (Zn) and iron (Fe) deficiencies are common in Guatemala, and maize is a staple food throughout the country. The primary aim of this study is to demonstrate if utilizing nixtamalized biofortified maize has the potential to…
- Trial name
- NCT06650397
- Testing
- Biofortified maize
- Where
- Guatemala
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Actinic Keratosis, Acne/Rosacea
Using a Cold Atmospheric Plasma Device to Treat Skin Disorders
This study examines the efficacy of a non-thermal, atmospheric plasma device in the treatment of skin disorders
- Conditions
- Actinic Keratosis, Acne/Rosacea, Verruca Plana, Tinea
- Trial name
- NCT02759900
- Testing
- Non-thermal, atmospheric plasma to treat skin lesions and acne, Indirect non-thermal, atmospheric plasma to treat hair loss and acne
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Skin Center Dermatology Group
Ichthyosis
An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses
The ichthyoses are a group of lifelong genetic disorders that share characteristics of generalized skin thickening, scaling and underlying cutaneous inflammation.
- Trial name
- NCT04549792
- Testing
- Ustekinumab
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwestern University
Irritable Bowel Syndrome
Dieta Mediterranea e Sindrome Dell'Intestino Irritabile in Pazienti Pediatrici
The goal of this observational study is to observe pediatric patients with IBS (irritable bowel syndrome). The main question it aims to answer are: adherence to the Mediterranean diet of children with IBS in patients not adhering…
- Trial name
- NCT05738343
- Testing
- dieta mediterranea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Netherton Syndrome
A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome
This study is open to people with a skin disease called Netherton syndrome (NS). People can join the study if they are 12 years or older.
- Trial name
- NCT05856526
- Testing
- Spesolimab - solution for infusion, Spesolimab - solution for injection
- Where
- 28 sites in United States, Australia and 12 more
- Volunteers
- 43 people
- Sponsor
- Boehringer Ingelheim
Ichthyosis
Patient Study to Evaluate the Safety and Emollient Performance of Doublebase Once in the Treatment of Ichthyosis
28 Day Survey study in patients with Ichthyosis
- Trial name
- NCT07783165
- Testing
- Doublebase Once
- Volunteers
- 100 people
- Sponsor
- Dermal Laboratories Ltd
Oral Neoplasm
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment
The purpose of this observational study is to evaluate the utility of the S100A7 immunohistochemistry signature-based assessment - STRATICYTE - in determining the risk of progression to cancer of clinically suspicious oral…
- Trial name
- NCT04622462
- Testing
- Standard of Care Histopathology, STRATICYTE Assessment
- Where
- 3 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Proteocyte Diagnostics Inc.
Netherton Syndrome
Natural History of Netherton Syndrome
The goal of this non-interventional study (NIS) is to collect real-world data to describe the natural history of Netherton Syndrome (NS).
- Trial name
- NCT05902663
- Where
- 4 sites in United States, Italy
- Volunteers
- 4 people
- Sponsor
- Boehringer Ingelheim
Autosomal Recessive Congenital Ichthyosis, Epidermolytic Ichthyosis
Study of in Vivo and in Vitro Transcriptomic and Proteomic Signatures in Unhereditary Ichtyosis
The goal of this study is to identify important biological pathways involved in a variety of ichtyosis, using transcriptomic and proteomic techniques, with the aim of guiding the development of new therapeutis.
- Trial name
- OMICHTYOSE (NCT05312073)
- Testing
- Biological samples, Skin biopsy
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Congenital Ichthyosis
A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis
The purpose of this study is to investigate the efficacy and safety of two concentrations of topically applied ointment formulation of isotretinoin called TMB-001 (0.05% and 0.1% isotretinoin) in subjects 9 years of age and older…
- Trial name
- NCT04154293
- Testing
- Isotretinoin, Vehicle
- Where
- 11 sites in United States, Australia
- Volunteers
- 34 people
- Sponsor
- LEO Pharma
Chronic Otitis Media, Cholesteatoma
A Study of the Clinicopathologic Behaviour of the Different Types of Unsafe Chronic Otitis Media
The purpose of the study is to study the clinicopathologic behaviour of the 3 dangerous types of chronic otitis media that are prone for complications.
- Trial name
- NCT00270660
- Testing
- biopsy, audiometry, ET function test, ear swab culture, DNE
- Where
- India
- Volunteers
- 192 people
- Sponsor
- Karnataka Institute of Medical Sciences
Arsenical Melanosis, Arsenical Keratosis
Selenium in the Treatment of Arsenic Toxicity and Cancers
Context: Approximately 100 million people throughout the world consume water contaminated with arsenic at levels above carcinogenic thresholds, including 40 million in Bangladesh alone, with up to one-fourth of deaths attributed…
- Conditions
- Arsenical Melanosis, Arsenical Keratosis, Arsenical Cancers, Arsenicosis
- Trial name
- SETAC (NCT01442727)
- Testing
- sodium selenite
- Where
- Bangladesh
- Volunteers
- 819 people
- Sponsor
- Texas Tech University
Middle Ear Cholesteatoma
Associations of Pre- and Intraoperative Endoscopic Findings of Middle Ear Status in Cholesteatoma
The aim of this study is to assess the accuracy of preoperative HRCT of the temporal bone combined with the preoperative audiologic assessment compared with the intraoperative endoscopic middle ear finding.
- Trial name
- NCT04672187
- Where
- Thailand
- Volunteers
- 41 people
- Sponsor
- Prince of Songkla University
Actinic Keratoses
Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients
Skin cancers and pre-cancerous growths (called actinic keratoses, "AKs"), that aren't melanomas, develop in patients with a kidney transplant at excessive rates.
- Trial name
- NICE (NCT04843553)
- Testing
- Oral Nicotinamide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital