Clinical trials: IUD Complication
Cardiac Ion Channelopathy
Post-mortem Genetic Testing
This is a prospective observational study to examine the incidence of cardiac ion channelopathies in unexplained still births.
- Trial name
- NCT01120886
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Thayyil, Sudhin
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Stillbirth
The Midlands and North of England Stillbirth Study
The United Kingdom has one of the highest rates of stillbirth in Europe, with more than 4,000 stillbirths every year; which equates to more than 11 deaths every day.
- Trial name
- MiNESS (NCT02025530)
- Testing
- Questionnaire
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,030 people
- Sponsor
- University of Manchester
Stillbirth and Neonatal Mortality, Perinatal Mortality
Perinatal Mortality Outcomes Through Household Infection Pathways
The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh.
- Conditions
- Stillbirth and Neonatal Mortality, Perinatal Mortality, Infant Mortality, Child Mortality
- Trial name
- POTH (NCT07620613)
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Stanford University
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Malaria, Stillbirths
The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria
The purpose of this study is to test the feasibility of the scale-up of sulphadoxine- pyrimethamine (SP) for the preventive treatment of malaria in pregnancy in three Local Government Areas (LGAs) in Sokoto State, Nigeria.
- Trial name
- MIPP-NG (NCT02758353)
- Testing
- Community distribution of SP
- Volunteers
- 31,493 people, healthy volunteers welcome
- Sponsor
- JSI Research & Training Institute, Inc.
Neonatal Death, Stillbirth
Asia Pregnancy Outcomes Study
Preterm birth is a major cause of child mortality and morbidity, most of which occurs in south-east Asia and sub-Saharan Africa.
- Trial name
- NCT03438110
- Where
- 3 sites in India, Pakistan
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- RTI International
Decreased Fetal Movements Affecting Care of Mother, Pregnancy
Promoting Awareness Fetal Movements to Reduce Fetal Mortality Stillbirth, a Stepped Wedge Cluster Randomised Trial.
Rates of stillbirth in Scotland are among the highest in resource rich countries. The majority of stillbirths occur in normally formed infants, with (retrospective) evidence of placental insufficiency being the commonest clinical…
- Conditions
- Decreased Fetal Movements Affecting Care of Mother, Pregnancy, Stillbirth
- Trial name
- AFFIRM (NCT01777022)
- Testing
- A package of interventions
- Where
- 29 sites in Ireland, United Kingdom
- Volunteers
- 430,830 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Anemia, Low Birth Weight
Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia
Background: Maternal and child under-nutrition is the underlying cause of death for millions across the globe. Anemia during pregnancy is among the leading nutritional disorders with serious short and long term consequences to…
- Conditions
- Anemia, Low Birth Weight, Pre-Term Birth, Still Birth
- Trial name
- NCT02620943
- Where
- Ethiopia
- Volunteers
- 374 people
- Sponsor
- Dilla University
Stillbirth
The Tommy's National Rainbow Clinic Study
The death of a baby before or shortly after birth affects approximately 1 in every 250 pregnancies in the UK meaning that over 4,000 parents experience the death of a baby each year in the UK.
- Trial name
- NCT04393259
- Testing
- Rainbow Clinic Model of Antenatal Care
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University of Manchester
Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes
The objective of our study is to investigate the association of umbilical cord abnormalities with adverse pregnancy outcomes. The umbilical cord parameters that will be investigated as part of this study include the umbilical…
- Conditions
- Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy, Stillbirth, Admission to Neonatal Unit
- Trial name
- ULOOP (NCT05901688)
- Testing
- Umbilical cord measurements & observations
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Medway NHS Foundation Trust
Asherman's Syndrome
Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
The purpose of this study is to compare the outcome of loop intrauterine contraceptive device and heart-shaped intrauterine balloon for the adjunctive treatment of severe intrauterine adhesions in patients with infertility.
- Trial name
- ROABTIPWSIUA (NCT02708277)
- Testing
- loop-shaped intrauterine contraceptive device, intrauterine balloon (Cook Medical)
- Volunteers
- 93 people
- Sponsor
- Yuqing Chen
Maternal Death, Maternal Morbidity
BetterBirth: A Trial of the WHO Safe Childbirth Checklist Program
The purpose of this study is to measure the impact of a checklist-based childbirth safety program (the WHO Safe Childbirth Checklist Program) on reduction of severe maternal, fetal, and newborn harm in institutional deliveries in…
- Conditions
- Maternal Death, Maternal Morbidity, Stillbirth, Neonatal Death
- Trial name
- BetterBirth (NCT02148952)
- Testing
- WHO Safe Childbirth Checklist Program
- Where
- India
- Volunteers
- 157,689 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Perinatal Morbidity, Morbidity;Perinatal
Multicentric Retrospective Study of Perinatal Mortality
Background: Perinatal mortality ranges mortality from 22 gestational weeks up to the first 7 days of life and extended mortality goes up to 28 days of life.
- Conditions
- Perinatal Morbidity, Morbidity;Perinatal, Stillbirth, ICD
- Trial name
- PM-PHD-NTM (NCT05491772)
- Where
- Spain
- Volunteers
- 468 people
- Sponsor
- Corporacion Parc Tauli
Premature Birth, Perinatal Mortality
Assessing the Impact of Smoke-free Legislation on Perinatal Health in the Netherlands
The purpose of this study is to investigate whether there has been a change in perinatal outcomes following the phased smoking ban introduction (January 2004 for workplaces; July 2008 for bars and restaurants) workplaces in the…
- Conditions
- Premature Birth, Perinatal Mortality, Infant, Low Birth Weight, Stillbirth
- Trial name
- NCT02189265
- Testing
- Smoke-free legislation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 2,069,695 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
IUD, Healthy Female
Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement
Intrauterine devices (IUDs) are a popular form of long-acting reversible contraception, with a high efficacy rate and few side effects. The insertion procedure for IUDs can be uncomfortable and painful.
- Conditions
- IUD, Healthy Female, Contraception, IUD Insertion Complication
- Trial name
- NCT05875571
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Brain Malformation
Comparison of Abnormal Cortical Development in Brain Malformations on Postmortem Imaging With Autopsy
Examination of the fetal brain at autopsy is technically challenging because of marked fragility of the brain tissue. Studies have found postmortem fetal MR to be particularly useful in examining gross structural abnormalities in…
- Trial name
- NCT00686530
- Testing
- MR Imaging, Autopsy
- Where
- 2 sites in Canada
- Sponsor
- The Hospital for Sick Children
Stillbirth, Newborn Death
The Paediatric Virtual Autopsy Trial
In light of declining autopsy rates around the world, post-mortem MR imaging is a promising alternative to conventional autopsy in the investigation of infant death.
- Conditions
- Stillbirth, Newborn Death, Sudden Infant Death
- Trial name
- NCT01888380
- Testing
- Minimally invasive, virtual autopsy, Conventional autopsy
- Where
- 4 sites in Switzerland
- Volunteers
- 105 people
- Sponsor
- University of Zurich