Clinical trials: Iatrogenic Effect
Traumatic Brain Injury, Ventilator Associated Pneumonia
Effect of E-BAL on Severity of VAP Assessed Through CPIS on the Patients of Traumatic Brain Injury in Neurocritical Care, Also Effect on Days of Ventilation and ICU Stay.
Severe traumatic brain injury (STBI) is a leading cause of disability, mortality, and economic burden worldwide. The impact of severe traumatic brain injury (STBI) on the economy of developing countries like Pakistan is…
- Trial name
- NCT04977843
- Testing
- EARLY BRONCHOALVEOLAR LAVAGE
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Hospital
Burns, Wounds
Kerlix Gauze Study in a Burn Trauma Unit and Its Effect on Healthcare Associated Infections in Burn Patients
The purpose of this study is to determine whether Kerlix AMD gauze will decrease the incidence of healthcare associated infections in burn patients.
- Trial name
- NCT00656708
- Testing
- Kerlix AMD gauze
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Lucy A Wibbenmeyer
Nosocomial Infection, Necrotizing Enterocolitis
Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
The purpose of this study is to determine whether oral probiotic supplementation could reduce the incidence of nosocomial infections in preterm infants.
- Trial name
- NCT01340469
- Testing
- probiotics
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Hand Hygiene Practices Among Nurses, Nursing Education
Effects of Virtual Reality Hand Hygiene Simulation on Nurses' Hand Hygiene
Healthcare-associated infections (HAIs) are an important patient safety concern, and hand hygiene is one of the most effective measures for preventing their transmission.
- Conditions
- Hand Hygiene Practices Among Nurses, Nursing Education, Simulation Training, Virtual Reality
- Trial name
- NCT06788405
- Testing
- Virtual Reality Hand Hygiene Simulation, Standard Hand Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Askin Selvi
Iatrogenic Effect, Prescription
Optimization of Drug Prescriptions in the Care Pathway for the Elderly, With the Final Objective of Reducing the Iatrogenic Risk
The IATROPREV project is an organizational innovation experimentation project, carried out in Hauts-de-France by the University hospitals of Amiens and Lille, the ARS and the URPS Doctors and Pharmacists of Hauts-de-France and…
- Conditions
- Iatrogenic Effect, Prescription, Follow-up, Consultation
- Trial name
- IATROPREV (NCT05045235)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Ventilator Associated Pneumonia
Open Suction Circuit Flushing With Chlorhexidine Decreases Ventilator-Associated Pneumonia: A Quasi-experimental Study
Background: Standard practice of flushing saline over the patient's secretions following suctioning is similar to pouring water over grease, leading to motivating bacterial colonization and proliferation inside the suctioning…
- Trial name
- NCT05206721
- Testing
- Open tracheal suction system flushing with chlorhexidine
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Mansoura University
Blood Stream Infection
Topical Emollient Therapy
Almost all (99%) of the neonatal deaths occur in lower and middle income countries. Most of these deaths are attributable to prematurity and infection.
- Trial name
- NCT01396642
- Testing
- Topical Emollient
- Where
- 2 sites in Pakistan
- Volunteers
- 258 people
- Sponsor
- Aga Khan University
Pneumonia
Physiotherapy on Pneumonia in Childrens
The children's susceptibility to respiratory problems is due to their anatomical and physiological characteristics; therefore, children with more severe clinical conditions may undergo invasive mechanical ventilation (IMV).
- Trial name
- VAP (NCT03343717)
- Testing
- Rehabilitation, Chest physical therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Metodista de Piracicaba
Nosocomial Pneumonia, Healthcare-Associated Pneumonia
Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients
Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease incidence of pneumonia in patients undergoing open…
- Conditions
- Nosocomial Pneumonia, Healthcare-Associated Pneumonia, Aspiration Pneumonia, Ventilator-Associated Pneumonia
- Trial name
- NCT00610324
- Testing
- Chlorhexidine gluconate, Potassium permanganate
- Where
- India
- Volunteers
- 512 people
- Sponsor
- King Edward Memorial Hospital
Healthcare Associated Infection, Hand Hygiene
Effect of Video Camera Monitoring Feedback on Hand Hygiene Compliance and Infections in NICU
The purpose of this study is to determine if use of the video camera surveillance system for HH observation and performance feedback about HH compliance rates can improve the HH compliance of HCWs and reduce healthcare-associated…
- Conditions
- Healthcare Associated Infection, Hand Hygiene, Neonatal Infection
- Trial name
- CaM-HAI (NCT04053257)
- Testing
- Hand hygiene compliance observation with video camera surveillance system and performance feedback of the HH rates to HCWs
- Where
- Turkey (Türkiye)
- Volunteers
- 8,335 people, healthy volunteers welcome
- Sponsor
- Marmara University
Nosocomial Infection, Infection Control
Can Environmental Cleanliness be Assessed by BCA (Bicinchoninic Acid) Method
Effective cleaning of surfaces in the hospital environment is an absolute necessity to reduce pathogen transmission. Multi Drug Resistant Organisms (MDRO) in ICU are among the leading causes of hospital-acquired infections.
- Conditions
- Nosocomial Infection, Infection Control, Multi-antibiotic Resistance
- Trial name
- BCA (NCT04212130)
- Testing
- BCA method for assessing environmental cleanliness
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Nosocomial Infection, Diarrhea, Infantile
Effect and Tolerability of Lactobacillus Rhamnosus GG LA801 for the Preventive Nutritional Care of Nosocomial Diarrhea in Children
One of the most common infections acquired in hospital, also known as nosocomial infections, is intestinal infections. These infections can lead to the development of nosocomial diarrhea which can have serious consequences in…
- Trial name
- EPISODE (NCT04628819)
- Where
- 2 sites in France
- Volunteers
- 61 people
- Sponsor
- PiLeJe
Ventilator Associated Pneumonia, Etiological Organisms
A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia
Objective of this study was to determine incidence, risk factors, etiological micro-organisms and their antimicrobial susceptibility pattern and outcome of VAP; and to study effect of ranitidine vs.
- Conditions
- Ventilator Associated Pneumonia, Etiological Organisms, Antimicrobial Drug Susceptibility Pattern, Stress Ulcer Prophylaxis
- Trial name
- NCT00702871
- Testing
- Ranitidine, Sucralfate
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Maulana Azad Medical College
Pneumonia, Ventilator-Associated
Effect of Gravity on Tracheal Colonization During Mechanical Ventilation in Infants
Ventilator-associated pneumonia (VAP) is the leading cause of death among all nosocomial infections in ventilated patients. Once intubated, the risk of pneumonia in hospitalized patients is increased 3-10 fold; almost 90% of…
- Trial name
- NCT00491660
- Testing
- supine positioning, lateral positioning
- Volunteers
- 60 people
- Sponsor
- Cairo University
Ventilator Associated Pneumonia
Ventilator Associated Pneumonia Care Bundle Prevention on Internship Students' Knowledge and Clinical Performance
The goal of this clinical trial is to determine the effect of a self-instructional module regarding ventilator-associated pneumonia care bundle prevention on internship students' knowledge and clinical performance in pediatric…
- Trial name
- NCT06090019
- Testing
- Routine PICU nursing care for children on mechanical ventilator., Self-instructional module for VAP care bundle prevention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Ventilator Associated Pneumonia
Pravastatin and Ventilatory Associated Pneumonia
Statins present anti-inflammatory and immunomodulatory effects. They may modify the regulation of cytokines, (released from the cellular damage) and may reduce the production of C-reactive protein levels.
- Trial name
- EPRAVAP (NCT00702130)
- Testing
- Pravastatin
- Where
- 2 sites in Greece
- Volunteers
- 152 people
- Sponsor
- University of Thessaly
Intensive Care Unit, Health Care Associated Infection
The Effect of Care-oriented Practical Training on Nurses' Intensive and Critical Care Competency and HAIs Indicators
It was aimed to evaluate the effect of care-oriented practical training on the intensive and critical care competencies of nurses, the hand hygiene compliance rate of nurses and care support staff, and HAI indicators.
- Conditions
- Intensive Care Unit, Health Care Associated Infection, Patient-Centered Care, Competence
- Trial name
- NCT06239987
- Testing
- Care-oriented Practical Training
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Akdeniz University
Infections, Nosocomial, Infections, Respiratory Tract
Antibacterial Effect of Zinc Oxide Nanoparticles on Acinetobacter Baumannii Isolated From Patients With Hospital Acquired Infections in Sohag University Hospitals, Egypt
A. baumannii is known as the most frequently isolated organism in intensive care units (ICUs), causing a variety of nosocomial infections, including pneumonia, urinary tract infections (UTIs), bacteremia as well as skin and soft…
- Trial name
- NCT06628076
- Testing
- Culture specific antibiotic therapy, Antibiotic, Biofilm assessment
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Ventilator Associated Pneumonia
Effect of Educational Program About Preventive Care Bundle for Prevention of Ventilator Associated Pneumonia Among Newborns
This study is designed to investigate the effect of educational program for nurses about preventive care bundle for prevention of ventilator associated pneumonia among newborns.
- Trial name
- NCT06066489
- Testing
- educational program about VAP
- Volunteers
- 137 people
- Sponsor
- Damanhour University
Health Care Associated Infection, Skin
Effect Of Bath Wıth Chlorexıdıne On Protectıon Of Skın Integrıty And Preventıon Of Hospıtal Infectıon
The study was designed in a randomized controlled experimental design type to determine the effect of a 2% chlorhexidine bath applied in the pediatric intensive care unit on protecting skin integrity and preventing…
- Trial name
- NCT05844683
- Testing
- 2% chlorhexidine digluconate solution, usual baths
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Okan University