Clinical trials: Image Reconstruction
Anterior Cruciate Ligament Injury, Quadriceps Dysfunction
Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
FROM RISK FACTORS TO THE PREVENTION OF LONG-TERM CONSEQUENCES AFTER CRUCIATE LIGAMENT INJURY (ACL injury) - This is a research project where we seek new knowledge about why some people have a high risk and others a low risk of…
- Conditions
- Anterior Cruciate Ligament Injury, Quadriceps Dysfunction, Knee Joint Loading, Anterior Cruciate Ligament Reconstruction
- Trial name
- ExeLoadBioPTOA (NCT06892899)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- May Arna Risberg
Zygomatic Fractures
Evaluation of Navigation Assisted Reconstruction of Posttraumatic Zygomatic Deformity
Treatment of late deformities following fractures of the orbitozygomaticomaxillary complex can be considered a formidable challenge, even to the skilled surgeon.
- Trial name
- NCT01487018
- Testing
- Navigation Surgery, Traditional Surgery
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Peking University
ACL, Meniscus Lesion
THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Purpose/reason of the research: The anterior cruciate ligament (ACL) is an important ligament in maintaining knee function. In patients with anterior cruciate ligament (ACL) injury, concomitant intra-articular lesions are usually…
- Conditions
- ACL, Meniscus Lesion, Sport Injury
- Trial name
- NCT05048420
- Testing
- surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Medipol University
Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament (ACL) Reconstruction- Bioabsorbable Screw
To evaluate the knee functionality, screw integrity, graft integrity, cartilage effect, and bony ingrowth in patients treated with the CALAXO screw and MILAGRO screw two years after ACL reconstruction.
- Trial name
- NCT01069588
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Limbal Stem Cell Deficiency, Stevens-johnson Syndrome
Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation
To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.
- Conditions
- Limbal Stem Cell Deficiency, Stevens-johnson Syndrome, Ocular Cicatricial Pemphigoid, Chemical Burn
- Trial name
- NCT02149732
- Testing
- cultivated oral mucosal epithelial sheet transplantation
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
- Trial name
- STABILITY 2 (NCT03935750)
- Testing
- Anterior cruciate ligament reconstruction (ACLR), Lateral extra-articular tenodesis (LET)
- Where
- 31 sites in United States, Canada and 6 more
- Volunteers
- 1,272 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Injury
MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation
This clinical trial evaluates interventions to maximize muscle function and improve cartilage health following anterior cruciate ligament reconstruction.
- Trial name
- MiACLR (NCT03626857)
- Testing
- Neuromuscular Electrical Stimulation (NMES), Eccentric Exercise (ECC)
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Michigan
Autografts, Blood Flow Restriction Therapy
Blood Flow Restriction Following ACLR w/Quad Autograft
This project is intended to acquire objective measurements of implementing BFR rehabilitation in ACL reconstructions to show any changes upon completion of the BFR protocol.
- Conditions
- Autografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle Strength
- Trial name
- BFR Quad Delay (NCT06636045)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Anterior Cruciate Ligament Rupture
Reconstruction of the ACL With QT Graft With Bone Plug vs BPTB
Background: Anterior cruciate ligament (ACL) injury is one of the most common orthopedic injuries worldwide. Currently, the use of the bone patellar tendon bone graft (BPTB) technique is considered the gold standard.
- Trial name
- NCT06189573
- Testing
- Anterior cruciate ligament Reconstruction with autologous quadriceps tendon graft, Anterior cruciate ligament Reconstruction with autologous bone patellar tendon bone graft
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
ACL Injury, Knee Injuries
Subjective Outcomes After ACL Reconstruction With BQT Autograft
The purpose of the study is to compare short-term patient reported outcome measures (PROM) of Bone-Quadriceps-Tendon (BQT) autograft with Semitendinosus-Gracilis (STG) and Bone-Patellar-Tendon-Bone (BPTB) autografts following…
- Trial name
- NCT04901559
- Testing
- Graft type at ACLR
- Volunteers
- 30,000 people
- Sponsor
- Region Zealand
Genetic Disorders
Face Anthropometric Pattern Recognition Technology for Computer Aided Diagnosis of Human Genetic Disorders.
The hypothesis to be tested: After the construction of a database of anthropometric measurements, the system would extract important features of a given facial surface and be able to match it with existing morphometric figures.
- Trial name
- DW-6/2007 (NCT00705055)
- Where
- 2 sites in Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
ACL Tear, Opioid Misuse
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR)…
- Conditions
- ACL Tear, Opioid Misuse, Pain, Anxiety
- Trial name
- NCT06274008
- Testing
- Exparel
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Anterior Cruciate Ligament Injuries
Reduce Opiate Exposure With ACL Surgery
This is a randomized control trial to investigate the effectiveness of a multimodal opiate sparing analgesic regimen in controlling post-operative pain and potentially reduce post-operative opioid consumption in patients…
- Trial name
- NCT06561035
- Testing
- Opiate Sparing, Opiate Based
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Campbell Clinic
Shoulder Dislocation, Bone Loss
Latarjet vs Anatomic Glenoid Reconstruction
Anterior shoulder dislocations occur when the humeral head translates anterior to the glenoid cause pain, stiffness, and glenoid bone loss. If left untreated, the risk of recurrence can be up to or greater than 90%.
- Conditions
- Shoulder Dislocation, Bone Loss, Arthroscopy
- Trial name
- NCT05658289
- Testing
- Coracoid Transfer, Distal Tibia Allograft with Bankart repair
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
ACL, Opioid Use
VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)
The goal of this project is to test the effects of the VibraCool mechanical stimulation neuromodulatory therapeutic device on post-operative pain and opioid use following anterior crucitate ligament reconstruction (ACLR), and…
- Conditions
- ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure
- Trial name
- NCT06456268
- Testing
- VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Columbia University
ACL Reconstruction
When do School-aged Patients Return to School After ACL Surgery?
We intend to survey school aged patients following ACL surgery on when they return to school. We will analyze independent variables to determine if any relationship exists that may influence the amount of time missed.
- Trial name
- NCT03929237
- Testing
- observe when return to school after surgery
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- St. Louis University
Mandible Reconstruction
Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction
The study aims to evaluate facial symmetry outcomes after mandibular reconstruction using fibula free flaps, comparing two fixation techniques: the prosthetically favorable position (alveolar level) and the conventional position…
- Trial name
- NCT06790628
- Testing
- Fibula free flap
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Vaginal Cancer
Immediate Vaginal Reconstruction After Oncologic Resection: Surgical Outcomes, Patient Satisfaction and Sexual Function
This study is being done to find out more about the experience women have with vaginal reconstruction. We hope to learn about their quality of life, sexual function, and body image.
- Trial name
- NCT00588081
- Testing
- QOL
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
ACL Tear
Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL…
- Trial name
- NCT05532189
- Testing
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University