Clinical trials: Implementation Science
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
HPV Vaccine
Effectiveness of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination in China
This interventional study targets female students in junior middle school. It goal is to evaluate the effectiveness of a vaccine chatbot on HPV vaccine awareness and vaccination. The main questions it aims to answer are: 1.
- Trial name
- NCT06227689
- Testing
- Vaccine chatbot that offering HPV vaccine-related information
- Where
- 2 sites in China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Fudan University
Developmental Language Disorder
Training Caregivers to Teach Vocabulary to Children With Language Impairment
The purpose of this study is to determine whether Spanish-speaking caregivers can learn to teach science vocabulary to their children with the use and educational app and a short training video with target words.
- Trial name
- DLD (NCT07519629)
- Testing
- Robust vocabulary intervention
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Northern Arizona University
Implementation, Behavioral Symptoms
Working to Implement and Sustain Digital Outcome Measures
This study will investigate the effects of an organizational implementation strategy called Leadership and Organizational Change for Implementation (LOCI), relative to training and technical assistance only, on fidelity to, and…
- Trial name
- WISDOM (NCT04096274)
- Testing
- Leadership for Organization Change and Implementation (LOCI), Training and Technical Assistance Only
- Where
- 4 sites in United States
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Boise State University
Health Behavior, Adolescence
THRIVE-Belize: A School-Based Life-Skills Program to Support Teen Health in Toledo District, Belize (Feasibility)
THRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize.
- Conditions
- Health Behavior, Adolescence, Feasibility Studies
- Trial name
- THRIVE-Belize (NCT07687199)
- Where
- Belize
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Red Blood Cell Transfusions
Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit
Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and…
- Trial name
- TRIP (NCT07108374)
- Testing
- Implementation strategies to increase use of transfusion recommendations
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Neonatal Death, Perinatal Death
CHV-NEO: Community-based Digital Communication to Support Neonatal Health
Neonatal mortality (defined as death in the first 28 days of life) remains unacceptably high in sub-Sarahan Africa. The concentrated risk of neonatal illness in the first weeks of life and its potential to rapidly deteriorate…
- Trial name
- NCT05187897
- Testing
- CHV-NEO
- Where
- Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cancer, Late Effects
FRAME - Implementation of a PRO Measure to Inform Patient-Centered Survivorship Care in Oncology Outpatient Visits
FRAME is a patient-centered survivorship care model embedded in routine oncology visits. It consists of: (1) a pre-visit patient-reported questionnaire (FRAME-PRO), (2) a clinician-patient dialogue guided by the responses, and…
- Trial name
- FRAME (NCT07281820)
- Testing
- FRAME model (questionnaire + dialogue + management plan)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Vejle Hospital
Congenital Heart Disease, Advanced Heart Failure
TORCH-LATAM-003: Regional Advanced-Therapy Pathways for Congenital Heart Disease
TORCH-LATAM-003 is a pragmatic stepped-wedge cluster randomized trial evaluating a regional pathway for children and adults with congenital heart disease and advanced cardiac and/or respiratory failure who may require heart…
- Conditions
- Congenital Heart Disease, Advanced Heart Failure, Respiratory Failure, Heart Transplantation
- Trial name
- TORCH-003 (NCT07837024)
- Testing
- TORCH Congenital Advanced Therapies Pathway (TORCH-CATP)
- Volunteers
- 360 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
Human Immunodeficiency Virus
Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
Having health workers assist HIV-infected persons with the recruitment and testing of their sexual contacts and biological children is an effective and efficient way of identifying additional HIV-infected persons in need of HIV…
- Trial name
- PRACTICE (NCT05343390)
- Testing
- Enhanced implementation package, Standard implementation package
- Where
- 33 sites in Malawi
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infection, Bacterial, Infection Prevention
Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU.
NeoDeco is a pragmatic, multicenter, parallel-group, cluster-randomised hybrid effectiveness-implementation trial designed to evaluate the impact of implementing optimised Kangaroo Care (KC) at the unit level compared to standard…
- Trial name
- NeoDeco (NCT05993442)
- Testing
- Optimised kangaroo care
- Where
- 24 sites in Greece, Italy and 3 more
- Volunteers
- 3,080 people
- Sponsor
- PENTA Foundation
Cognitive Function, Functional Status
Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0
Implementing a Skills-Based Caregiver Training (Caregivers FIRST): Function QUERI 2.0 aims to compare implementation strategies for large-scale spread of Caregivers FIRST, a group training for friend or family caregivers of…
- Trial name
- NCT05319535
- Testing
- Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Bronchiolitis Acute Viral
Eliminating Monitor Overuse Trial (EMO Trial)
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
- Trial name
- NCT05132322
- Testing
- Educational Outreach, Audit & Feedback (unit level), Audit & Feedback (real time, individual-level)
- Where
- 51 sites in United States, Canada
- Volunteers
- 9,265 people
- Sponsor
- Children's Hospital of Philadelphia
HIV Positive
Implementation and Effectiveness of a Psychosocial Intervention Among Registered People Living With HIV(HIV Patients) at Pakistan Institute of Medical Sciences (PIMS) Islamabad Pakistan.
"Implementation and Effectiveness of a Psychosocial Intervention Among Registered PLHIV at PIMS Islamabad Pakistan." The study aims to evaluate the impact of a structured psychosocial intervention on the mental health and…
- Trial name
- PLHIV (NCT06869330)
- Testing
- psychosocial
- Where
- Pakistan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Medication Errors, Patient Safety
Safety Action Feedback and Engagement (SAFE) Loop
This trial will test whether a new intervention, the Safety Action Feedback and Engagement (SAFE) Loop, enhances nurse incident reporting practices, improves nurses' perceptions of incident reporting, and lowers rates of…
- Trial name
- NCT05381441
- Testing
- Safety Action Feedback and Engagement (SAFE) Loop
- Where
- United States
- Volunteers
- 5,163 people
- Sponsor
- Cedars-Sinai Medical Center
Adolescent Development, Peer Group
Implementing Digital Peer Support Training for Adolescent Mental Health
Using a hybrid type III trial with a cluster randomized design, the digital peer support training for adolescent mental health protocol aims to implement a multidisciplinary program, which translates theoretical and empirical…
- Conditions
- Adolescent Development, Peer Group, Mental Health Wellness 1
- Trial name
- NCT05199675
- Testing
- Digital Peer Support Training Program
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The N.1 Institute for Health (N.1)
Malaria
Integrating the Guardian Spatial Emanator Within AVENIR II
This study will evaluate the implementation of integrating Guardian spatial emanators into the existing AVENIR II azithromycin mass drug administration program in Niger.
- Trial name
- GUARD-AV (NCT07712263)
- Testing
- Spatial Emanator
- Where
- Niger
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Asthma in Children, Implementation Science
Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care
This study aims to evaluate the effect of the implementation of the new Asthma Integrated Care Pathway in the Basque Healthcare Service for the improvement of care for children with asthma attacks and the reduction of variability…
- Trial name
- NCT06437444
- Testing
- The implementation strategy to encourage the adoption of the Care Pathway
- Where
- Spain
- Volunteers
- 249 people
- Sponsor
- Basque Health Service
Asthma, Asthma in Children
Asthma Implementation Research Trial
Asthma is the most common chronic disease among children worldwide, with 80% of asthma related deaths occurring in low- and middle-income countries (LMICs), such as Peru.
- Trial name
- AIRE (NCT03986177)
- Testing
- Self-management Intervention Package
- Where
- Peru
- Volunteers
- 110 people
- Sponsor
- Johns Hopkins University