Clinical trials: Implementation Strategies
Physical Activity
STEP Together: An Effectiveness-Implementation Study of Social Incentives and Physical Activity
Higher levels of physical activity have been demonstrated to improve health across a wide range of contexts and reduce cognitive decline as adults become older, but more than half of all adults in the United States do not meet…
- Trial name
- NCT04942535
- Testing
- Social Incentive Gamification, Social Goals through Incentives to Charity, Daily Performance Feedback
- Where
- United States
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cardiovascular Risk Factors, Clinical Practice Guideline
Development, Implementation and Evaluation of the Impact of a Guideline in Clinical Practise for Cardiovascular Risk
The aim of this study is to evaluate the impact of a clinical guideline in cardiovascular risk, with a local adaptation model of the existing guidelines in clinical practise at present, of each of the different cardiovascular…
- Conditions
- Cardiovascular Risk Factors, Clinical Practice Guideline, Implementation Strategies, Primary Care
- Trial name
- NCT01270022
- Testing
- Implementation, dissemination
- Where
- Spain
- Sponsor
- Gerencia De Atencion Primaria Area 2 De Madrid
Hypertension, Hypertensive Patients
DCP3 Based Multi-component Intervention for Hypertension Management and Control
This study aims to enable delivery of a multi-component intervention comprising of strategies based on Disease Control Priorities 3rd edition for management of hypertension among hypertensive patients.
- Trial name
- NCT04336631
- Testing
- Intervention on DCP3 based strategies for Hypertension Management and Control
- Where
- Pakistan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Implementation Science, Type 1 Diabetes in Adolescence
Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching
The goal of this study is to learn if toolkits of implementation strategies (e.g., provider and staff education, clear plan for how to refer and bill) help pediatric type 1 diabetes medical and psychology providers deliver a…
- Conditions
- Implementation Science, Type 1 Diabetes in Adolescence, Implementation Strategies
- Trial name
- NCT07766811
- Testing
- Base Implementation Toolkit (BIT), BIT-Enhanced, BIT-Sustainment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Lymphatic Filariases, Onchocerciasis
Prevalence of LF Infection in Districts Not Included in LF Control Activities
Lymphatic filariasis is a neglected tropical disease earmarked for elimination as a public health problem by the year 2020. Since the year 2000, the Global Program for the Elimination of LF has together with endemic countries…
- Trial name
- NCT03131401
- Testing
- Diagnosis of lymphatic filariasis, Diagnosis of lymphatic Filariasis and onchocerciasis, DEC Patch
- Where
- Ghana
- Volunteers
- 3,736 people
- Sponsor
- Noguchi Memorial Institute for Medical Research
Frailty, Disability
Multidisciplinary Mobile Unit for Preventing Hospitalization of Nursing Home Residents
Elderly patients residing in nursing homes are particularly at risk of experiencing urgent medical problems needing admission to the Emergency Department (ED).
- Conditions
- Frailty, Disability, Multimorbidity, Respiratory Failure
- Trial name
- MMU-1 (NCT04085679)
- Testing
- Multidisciplinary Mobile Unit (MMU)
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Sustainability
Sustainability and Precision Prevention Project
This is a five-year hybrid type 3 effectiveness-implementation study evaluating multilevel strategies to sustain a nationwide implementation of an evidence-based HIV prevention curriculum in schools.
- Trial name
- NCT07153042
- Testing
- Biweekly monitoring and feedback (BMF), Site-based assistance and mentorship (SAM), Enhanced site-based assistance and mentorship (Enhanced SAM)
- Where
- The Bahamas
- Volunteers
- 3,705 people
- Sponsor
- University of Massachusetts, Worcester
Acceptability, Feasibility Studies
Digital Support Strategies for Caregiver Home Practice
This project is a pilot trial of the Engaging Families home practice smartphone application (or "app") as an add on to a family-based prevention program.
- Trial name
- NCT06907966
- Testing
- Engaging Families home practice app, Scheduling app
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Arizona State University
HIV/AIDS
HIV Awal (Early) Testing & Treatment Indonesia Project Observational Phase
This study will be one of the first to systematically evaluate strategies to improve the implementation of a T\&T strategy in a concentrated epidemic in Asia.
- Trial name
- NCT03429842
- Volunteers
- 2,071 people
- Sponsor
- Gadjah Mada University
Clinical Trial
Primary Care Evidence-based Approach for Improving Lifelong Health
This study investigates the implementation and effectiveness of the Family Check-Up 4 Health (FCU4Health) intervention in primary care settings for reducing cardiovascular disease risk in children.
- Trial name
- PREVAIL (NCT06526312)
- Testing
- SMS/Text (CAMPI), Fidelity Monitoring (Lyssn and COACH), Family Check-Up 4 Health (FCU4Health)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Arizona State University
Healthy Lifestyle, Nursing
Evaluation of an Implementation Strategy of mHealth Intervention to Promote Healthy Lifestyles (E-VIDAPP Pilot Study)
The translation of beneficial interventions for the population into professional practice represents a constant challenge. Moreover, implementation of this evidence into clinical practice has been limited to date.
- Trial name
- E-VIDAPP (NCT05506436)
- Testing
- Evident 3, Implementation strategy
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Sickle Cell Disease, Depression
Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment
African Americans living with chronic health conditions are more likely to experience depression and other mental health disorders than their healthy counterparts, and are more likely to experience severe depression than whites…
- Conditions
- Sickle Cell Disease, Depression, Anxiety
- Trial name
- NCT04587661
- Testing
- off-the-shelf digital CBT, adapted digital CBT
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pittsburgh
Mental Health Disorder
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions.
The present research study will involve investigating the efficacy of large-scale dissemination models of evidence-based character strength interventions in secondary schools in Kenya.
- Trial name
- NCT05365503
- Where
- 3 sites in Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Attention Deficit Hyperactivity Disorder Symptoms
Caregiver Implementation Strategies Field Pre-Test
The purpose of this study is to field pre-test an implementation strategy resource package that aims to support caregivers in using behavioral interventions for children with hyperactive, inattentive, or impulsive behaviors.
- Trial name
- NCT06770036
- Testing
- Implementation Resource Package for Caregivers
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Addiction, Mental Health Disorder
Using NIATx Strategies to Implement Integrated Services in Routine Care
This is an implementation research study designed to evaluate a defined strategy, NIATx, for its effectiveness in installing and sustaining evidence-based integrated services for persons with co-occurring substance use and mental…
- Trial name
- NCT03007940
- Testing
- Coach Site Visit, Walk-through, Learning Sessions
- Volunteers
- 49 people
- Sponsor
- University of Wisconsin, Madison
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Post-traumatic Stress Disorder, Leadership
Testing the LOCI Intervention
The project will develop knowledge on how managers can lead the implementation of practices that have proven to be effective for post-traumatic stress disorders (PTSD) in child and adult specialized mental health services.
- Trial name
- NCT03719651
- Testing
- LOCI, EMDR, CT-PTSD
- Where
- Norway
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Malaria Infection, Malaria Vaccines
Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad
This is a two-arm, cluster-randomised, phase IV trial conducted in Chad to assess the protective efficacy and impact in real-life conditions of a new strategy for administering the R21/MM malaria vaccine, synchronized within a…
- Trial name
- COSAV-R21 (NCT07038837)
- Testing
- "Synchronised" arm (intervention)
- Where
- Chad
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Epicentre
Attention Deficit Hyperactivity Disorder Symptoms
Implementation Strategy Resource Package for Behavioral Classroom Interventions: Pilot Test
The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support teachers in using behavioral classroom management interventions for children with…
- Trial name
- NCT05489081
- Testing
- Positive Behavior Management Toolkit
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Breast Cancer, Early Detection of Cancer
Strategies to Decentralize Breast Ultrasound in Rwanda
Diagnosing breast cancer early is critical to reduce preventable breast cancer deaths in sub-Saharan Africa. This can be done in part through increasing patients' access to breast ultrasound, which is essential for evaluating…
- Conditions
- Breast Cancer, Early Detection of Cancer, Ultrasonography
- Trial name
- NCT06812208
- Testing
- Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback
- Where
- Rwanda
- Volunteers
- 1,792 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital