Clinical trials: Implementation Strategies
Posttraumatic Stress Disorder
Targeted Strategies to Accelerate Evidence-Based Psychotherapy (EBP) Implementation in Military Settings
This study will evaluate a program designed to increase military treatment facilities' use of Prolonged Exposure (PE), an evidence-based psychotherapy for PTSD.
- Trial name
- NCT03663452
- Testing
- Targeted Assessment and Context-Tailored Implementation of Change Strategies (TACTICS), Prolonged exposure training
- Where
- 8 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Adolescent HIV Infection, Transition to Adult Care
Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV
Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment.
- Conditions
- Adolescent HIV Infection, Transition to Adult Care, Implementation Science, Implementation Strategies
- Trial name
- ATTACH-Scale (NCT06924073)
- Testing
- ATP-Youth Enhanced Strategy (ATP-YES)
- Where
- 25 sites in Kenya
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- University of Washington
Evidence-Based Practices, CBT
A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy
This research project is a hybrid type 2 effectiveness-implementation trial that simultaneously examines (1) the effectiveness of a trauma-focused intervention for youth in the education sector and (2) the impact of a…
- Conditions
- Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
- Trial name
- NCT04451161
- Testing
- Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anterior Cruciate Ligament Injuries, Concussion, Brain
Making Football Safer for Women: Implementing an Injury Prevention Program
The aim of this study is to determine how we can best support coaches to implement an injury prevention (IP) program (Prep-to-Play) in female community Australian Football.
- Conditions
- Anterior Cruciate Ligament Injuries, Concussion, Brain, Musculoskeletal Injury
- Trial name
- Prep-to-Play (NCT04856241)
- Testing
- Coaching, Peer support, Educational materials
- Where
- Australia
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- La Trobe University
Acculturative Stress, Mental Health
Piloting a Learning Collaborative for School-Based Bilingual Providers Delivering Evidence-Based Interventions
This pilot feasibility trial is designed to evaluate an adapted Learning Collaborative (LC) as an implementation strategy to support delivery of the Supporting Transition Resilience of Newcomer Groups (STRONG) intervention in…
- Trial name
- SABER (NCT07471633)
- Testing
- STRONG, Learning Collaborative
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Oregon
Suicidal Self-directed Violence, Suicidal Preparatory Behavior
Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth
Scientific advances are constantly leading to better treatments. However, it is quite challenging for healthcare systems, including VA, to ask very busy providers to change the way they practice.
- Trial name
- MIDAS SPCT (NCT06011759)
- Testing
- Academic Detailing (AD), LEAP
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Point of Care STI Testing
Point of Care STI Testing
The proposed research hypothesizes that point-of-care testing (POCT) for sexually transmitted infections (STIs) gonorrhea and chlamydia will be a feasible, acceptable, and appropriate implementation strategy for improving HIV…
- Trial name
- NCT06844045
- Testing
- Gonorrhea/chlamydia Point-of-Care Testing
- Where
- United States
- Volunteers
- 6,460 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Kidney Diseases
Validation, Implementation, and Cost-analysis of a Strategy for Personalized Diagnosis of Rare Kidney Diseases
Chronic kidney disease (CKD) affects about 10% of the world population, with high morbidity and mortality. Genetic kidney diseases are increasingly recognized across all age groups and represent over 20% of all the causes of CKD.
- Trial name
- NCT06324136
- Testing
- Implementation of the diagnostic algorithm
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Meyer Children's Hospital IRCCS
Breastfeeding
Implementation Strategy for a Breastfeeding Guideline in Primary Care
The purpose of this study is to determine whether an implementation strategy for a breastfeeding guide is more effective than the usual practice (simple circulation of the guide) in terms of increasing the percentage of children…
- Trial name
- NCT01474096
- Testing
- implementation strategy of Breastfeeding
- Where
- Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Pediatric Solid Tumors
Molecular Characterization of Genetic Alterations in Pediatric Solid Tumors
Background: In Argentina, central nervous system (CNS) solid tumors (19%) and non-CNS solid tumors (25%) account for 44% of pediatric tumors.
- Trial name
- NCT04773808
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Covid19
Implementation of COVID-19 Testing Strategies in Community Health Centers
This project is part of a competitive revision to accelerate COVID-19 testing in underserved populations. The overall aim is to implement strategies to expand COVID testing in hotspot communities in MA, through 6 community health…
- Trial name
- NCT04802187
- Testing
- RADx CHCs testing intervention strategy, Usual care control
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Systemic Lupus Erthematosus (SLE)
Team-based Implementation of Hypertension Management in Childhood Lupus
The goal of this study is to compare the effectiveness of widely used implementation strategies to promote adherence to guideline-concordant evidence-based practices for monitoring and controlling blood pressure in patients with…
- Trial name
- ABOUT TIME (NCT07792733)
- Testing
- Health Navigator Engagement, Team Charter with Performance Monitoring, Pre-visit worksheet
- Volunteers
- 1,200 people
- Sponsor
- Boston Children's Hospital
Contraception Behavior
Implementation Strategy for a Peer-based Intervention to Prevent Teen Pregnancy
Previously studied peer-based educational videos on LARC (long-acting reversible contraceptive) devices will be incorporated into a high school health curriculum. This will then be administered to the intervention high school.
- Trial name
- NCT04578093
- Testing
- LARC peer-based curriculum
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Common Mental Disorders
Evaluating the Effectiveness of Multifaceted Implementation Strategies for Implementing a Guideline for the Prevention of Common Mental Disorders at the Workplace in Schools
Given today's high prevalence of common mental disorders and related sick leave among teachers an urgent need exists for a more sustainable working life for this professional group.
- Trial name
- NCT03322839
- Testing
- Multifaceted implementation strategies, Single implementation strategy
- Where
- Sweden
- Volunteers
- 732 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Completion of Three Dose Series of HPV, Improvement in Vaccine Intervals Between HPV Doses
The Efficacy of Reminders to Complete HPV Series
The human papillomavirus (HPV) vaccine is routinely recommended for both adolescent girls and boys starting at age 11, although it can be offered as young as 9 years of age.
- Trial name
- ICHAT (NCT01731496)
- Testing
- Telephone reminder, Text Message reminder
- Where
- 3 sites in United States
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Cancer
Developing Screening Clinical Breast Examination Implementation Strategies in South Africa
The goal of this observational study is to engage with multilevel stakeholders to collaboratively and to systematically develop a suite of strategies for implementing breast cancer screening using clinical breast examination…
- Trial name
- NCT06233383
- Where
- South Africa
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Physical Activity
Developing and Testing an Implementation Strategy for Active Learning to Promote Physical Activity in Children
The purpose of this study is to develop an implementation strategy to improve the use and sustainment of active learning in elementary schools and to conduct a feasibility study to evaluate the impact of the developed…
- Trial name
- NCT05048433
- Testing
- Implementation strategy for active learning to promote physical activity, Usual implementation support
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Dietary Behaviors, Fruit Consumption
A Comparative Intervention Study on Strategies for Fruit Distribution and Awareness Campaigns in Schools
This implementation study evaluates two strategies to increase fruit consumption among Swedish students. (1) installing fruit stands in schools and (2) combining fruit stands with a health-awareness campaign.
- Conditions
- Dietary Behaviors, Fruit Consumption, Dietary Habits, Healthy Eating
- Trial name
- NCT07385820
- Testing
- Fruit Stand Availability, Awareness Campaign
- Where
- 2 sites in Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Post Traumatic Stress, Overall Functioning
Randomized Controlled Trial of Supervision Strategies to Improve Clinician Fidelity to Trauma-focused CBT
The primary goal of this study is to examine the impact of varying supervision strategies on clinician fidelity and client outcomes in a community-based setting.
- Conditions
- Post Traumatic Stress, Overall Functioning, Clinician Fidelity, Supervision
- Trial name
- STEPS (NCT01800266)
- Testing
- Supervision Practices of TF-CBT
- Where
- United States
- Volunteers
- 1,280 people
- Sponsor
- University of Washington
Assess Fidelity to Cognitive-behavioral Therapy for Youth
Project FACTS (Fidelity Accuracy: Comparing Three Strategies)
The objective is to compare the accuracy, costs, and cost-effectiveness of three fidelity measurement methods to assess fidelity to cognitive-behavioral therapy for youth.
- Trial name
- NCT02820623
- Testing
- Self-report, Chart-Stimulated Recall, Behavioral Rehearsal
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Northwestern University