Clinical trials: Incontinence, Urinary
Stress Urinary Incontinence (SUI), Postmenopausal Women
The Effectiveness of Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy in Postmenopausal Women With Stress Urinary Incontinence
The objective of this clinical trial is to investigate whether the combination of pelvic floor muscle training (PFMT) and topical estrogen is more effective in treating stress urinary incontinence (SUI) in postmenopausal women…
- Trial name
- NCT07186985
- Testing
- Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy, Vaginal estrogen
- Volunteers
- 115 people
- Sponsor
- Hanoi Medical University
Enuresis
Efficacy and Safety of Vitamin D Supplementation Combined With Alarm Therapy in Treating Nocturnal Enuresis
This prospective, randomized, two-arm, parallel-design controlled clinical trial aims to determine whether high-dose vitamin D supplementation combined with alarm therapy improves outcomes in children with primary monosymptomatic…
- Trial name
- NCT06508333
- Testing
- alarm therapy, Vitamin D3
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Xing Liu
Urinary Incontinence
Pacific Northwest Female Urinary Incontinence Treatment Digital Awareness Project
The investigators will compare whether advertisements on Google or Facebook are more effective to reach women in the Pacific Northwest about treatment options for urinary incontinence through the American Urogynecologic Society's…
- Trial name
- PNW-IP (NCT04464928)
- Testing
- Facebook Advertisements, Google Advertisements
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Urinary Incontinence, Spinal Cord Injury
Lumbar to Sacral Ventral Nerve Re-Routing
To assess the level of improvement in voiding function after lumbar to sacral ventral nerve re-routing procedure in Spinal Cord Injury and spina bifida patients
- Conditions
- Urinary Incontinence, Spinal Cord Injury, Spina Bifida
- Trial name
- NCT00378664
- Testing
- lumbar to sacral ventral nerve re-routing procedure
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kenneth Peters, MD
Urinary Incontinence
Conservative Treatment of Postprostatectomy Incontinence
The primary purpose of this study is to test the effectiveness, impact on quality of life, and durability of non-surgical therapies for incontinence persisting at least one year after surgery.
- Trial name
- NCT00212264
- Testing
- Behavioral Therapy, Pelvic Floor Electrical Stimulation, Biofeedback
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enuresis, Nocturnal
Uroflowmetry and Nocturnal Enuresis
This study will evaluate the uroflowmetry parameters of patients which were treated for enuresis.
- Trial name
- NCT07028645
- Testing
- desmopressin melt form 120 μg, Desmopressin lyophilisate (Melt), Propiverine tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Furkan Adem Canbaz
Monosymptomatic Nocturnal Enuresis
Desmopressin Melt: Impact on Sleep and Daytime Functioning
Nocturnal enuresis affects 10% of the 7-year-old children and is essentially caused by a mismatch between nocturnal bladder capacity and the amount of urine produced during the night together with failure of the child to awaken…
- Trial name
- SLEEP (NCT01645475)
- Testing
- Desmopressin lyophilisate (Melt)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Urinary Bladder, Overactive, Overactive Bladder
Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet
The purpose of this clinical trial is to investigate whether adding high-dose vitamin D (2,400 IU daily) to standard medical treatment (solifenacin combined with behavioral therapy) is more effective than standard treatment alone…
- Conditions
- Urinary Bladder, Overactive, Overactive Bladder, Urinary Incontinence, Urge
- Trial name
- NCT06201013
- Testing
- urotherapy, Solifenacin Succinate, Vitamin D3
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Stress Urinary Incontinence
The Effect of Vaginal Estrogen Cream on Subjective and Objective Symptoms of Urodynamic Stress Incontinence
This is a randomized, double blinded placebo controlled trial over a period of 3 months. Study subjects will be randomized into 2 groups: Those receiving drug (1gm of estrogen vaginal cream [EVC] at bed time 3 times a week), and…
- Trial name
- NCT01123135
- Testing
- Vaginal ERT
- Where
- United States
- Sponsor
- University of California, Irvine
Treatment
TOT, TVT And Burch Colpo-Suspension for Treatment of Female Mixed Urinary Incontinence
This prospective interventional randomized controlled trial will recruit women with MUI scheduled for surgical treatment where patients will be randomized to either Burch colposuspension, TOT or TVT.
- Trial name
- NCT02775526
- Testing
- TOT, TVT, Burch Colposuspension
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Ain Shams University
Urinary Incontinence, Epispadias, Male
Autologous Muscle Stem Cell Therapy for Treatment of Congenital Urinary Incontinence in Epispadias Patients
The aim of this trial is to evaluate the safety and efficacy of an autologous muscle stem cell therapy in the treatment of congenital urinary incontinence in isolated epispadias.
- Trial name
- MUST (NCT04729582)
- Testing
- Primary human muscle stem cells (Satori-01)
- Where
- 2 sites in Germany
- Volunteers
- 21 people
- Sponsor
- Simone Spuler, MD
Urinary Incontinence
Evaluation Trial of Handheld Urinal for Adult Use
Usability and efficacy evaluation of a prototype handheld urinal for adult use
- Trial name
- NCT04897932
- Testing
- RS - WP06
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binding Sciences Limited
Urinary Stress Incontinence
Study Comparing the Use of Laser and of Kinesiotherapy for the Treatment of Female Stress Urinary Incontinence
The purpose of this study is compare the effect of laser and of kinesiotherapy in the treatment of women with stress urinary incontinence
- Trial name
- NCT03301142
- Testing
- Laser, kinesiotherapy
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Enuresis, Nocturnal, Ganglion
Ganglion Cell Thickness in Enuresis Nocturna
The precise role of the intrinsic circadian regulatory mechanism behind the pathogenesis of enuresis is not fully understood, but in theory, circadian rhythm irregularity may be the primary pathogenic mechanism not only for…
- Conditions
- Enuresis, Nocturnal, Ganglion, Circadian Rhythm Disorders
- Trial name
- NCT05126732
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Bakircay University
Enuresis
The Effect of Indomethacin in Monosymptomatic Enuresis Nocturnal
Monosymptomatic nocturnal enuresis, defined as the involuntary loss of urine during the night at an age where voluntary bladder control should have been attained and on the background of normal urinary tract function, is a rather…
- Trial name
- NCT00226122
- Testing
- Indomethacin
- Where
- Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Overactive Bladder, Parkinson Disease
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
The impact of urinary symptoms in Parkinson disease (PD) extends beyond worsened well-being. Urinary symptoms common in PD, especially incontinence and nocturia, are major risk factors for falls likely due to the combination of…
- Trial name
- BOSS PD (NCT03149809)
- Testing
- solifenacin, Pelvic floor muscle exercise-based behavioral therapy
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Attention Deficit Hyperactivity Disorder, Enuresis
The Effect of Methylphenidate on Primary Enuresis in Children With Attention Deficit Hyperactivity Disorder
To assess wether methylphenidate reduces the prevalence of primary nocturnal enuresis in children with attention deficit disorder
- Trial name
- NCT02699528
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Fecal Incontinence, Urinary Incontinence
Safety and Efficacy of Concurrent MACE and Mitrofanoff Procedures
This was a prospective study. The study period was from January 2022 to July 2025. The study included 30 patients suffering from combined fecal and urinary incontinence submitted for concurrent Malone Antigrade continent Enema…
- Trial name
- MitroMACE (NCT07206719)
- Testing
- Malone Antegrade Continent Enema (MACE) and Mitrofanoff procedures
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohammad Daboos
Primary Nocturnal Enuresis
A Cohort Study on Treating Primary Nocturnal Enuresis by Regulating Central-Peripheral Circadian Rhythm
Primary nocturnal enuresis (PNE), a prevalent pediatric disorder, suffers from therapeutic limitations characterized by low efficacy and high relapse rates.
- Trial name
- NCT07003126
- Testing
- Circadian Rhythm Intervention Combined with Bladder Training, Bladder Training (basic treatment for enuresis)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center