Clinical trials: Infant Developmental Assessment
Preterm Birth
Examination of the Relationship Between Home Affordances With Development
Babies with a history of premature birth and low birth weight are at risk for developmental disorders. These infants may have motor, cognitive and behavioral problems compared to their term peers.
- Trial name
- NCT05210985
- Testing
- Affordances in the Home Environment for Motor Development-Infant Scale, Peabody Developmental Motor Scales-2, Test Of Sensory Functions In Infants (Tsfı)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dysphagia of Newborn
Development of Dysphagia Evaluation Via Video Analysis Based on Deep Learning Method in Neonates and Infants and Correlation Between the Evaluation and the Development
The purpose of this study is to develop an evaluation of dysphagia through deep learning-based video analysis in newborns and infants, and to report the correlation with future development.
- Trial name
- NCT05204966
- Testing
- AI analysis
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Child Development
The Effect of a New Infant Formula on Growth and Cognition in Healthy Term Infants
This study is a multicenter, double-blind, randomized, controlled, parallel-designed, prospective trial and is intended to evaluate the nutritive effects of two staged study formulas on growth and cognitive outcomes.
- Trial name
- NCT04508257
- Testing
- Oral feeding of Investigational Formula (Stage 1&2), Oral feeding of Control formula (Stage 1&2), Breast feeding
- Where
- 3 sites in China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Malnutrition, Paediatric Failure to Thrive
Development and Evaluation of a New Infant Nutrition Screening Tool
A large number of children experience undernutrition related to or resulting from their illness. The NHS has recently published standards which state that all patients should be screened for undernutrition on admission and…
- Trial name
- iNEWS (NCT03323957)
- Testing
- nutritional screening tool
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Glasgow
Seizure in Participants With Tuberous Sclerosis Complex, Seizure in Participants With Dravet Syndrome
Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures
This study will be conducted to evaluate the safety, pharmacokinetics (PK), and efficacy of adjunctive GWP42003-P in participants < 2 years of age with tuberous sclerosis complex (TSC), Lennox-Gastaut syndrome (LGS), or Dravet…
- Conditions
- Seizure in Participants With Tuberous Sclerosis Complex, Seizure in Participants With Dravet Syndrome, Seizure in Participants With Lennox-Gastaut Syndrome
- Trial name
- NCT04485104
- Testing
- GWP42003-P
- Where
- 11 sites in United States, Italy and 1 more
- Volunteers
- 3 people
- Sponsor
- Jazz Pharmaceuticals
Neonatal Respiratory Failure
Development of Modified Combined Apgar Scoring System for Evaluation of Infants in the Delivery Room
Apgar scoring system has been widely used for the evaluation of the infant's postnatal condition. As conventional Apgar scoring system is affected by gestational age and resuscitative efforts, there is a need for development of…
- Trial name
- NCT03166826
- Testing
- Modified Apgar Scoring System
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Infant Development, Neonatal Intensive Care Unit
Individual Structured Therapy in Early Premature Infants at the Neonatal Intensive Care Unit
In this study, investigators aimed to apply an individual structured therapy protocol within the framework of neurodevelopmental therapy principles in early premature infants hospitalized in the neonatal intensive care unit and…
- Conditions
- Infant Development, Neonatal Intensive Care Unit, INDIVIDUALIZED THERAPY
- Trial name
- NCT06648213
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Food Allergy in Infants, Food Allergen Sensitisation
Human Breast Milk's Role in Food Allergy Development
The goal of this prospective cohort pilot study is to learn about food allergens being passed on in breast milk to breast feeding infants.
- Conditions
- Food Allergy in Infants, Food Allergen Sensitisation, Breast Feeding, Exclusive, Breastmilk Collection
- Trial name
- NCT06765213
- Testing
- Open Ended Oral Food Challenge, Early Introduction
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Infant Growth, Mothers' Parental Competence
Nursing and Nurturing Premature Infants
The purpose of this study is to determine whether systematic use of the Newborn Individualized Developmental Care Assessment Program (NIDCAP®) improves the neurologic development of children and the parental competence of mothers.
- Trial name
- NCT00388141
- Testing
- NIDCAP
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cognitive Development
Fatty Acid Levels and Memory in Breastfed Children
Purpose: To explore the relation between breastmilk nutrients and the cognitive abilities of breastfed infants. Phase 1: Near 3 months of age child and mother saliva samples for DNA obtained with breast milk sample.
- Trial name
- NCT01942434
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Neurodevelopmental Disorders, Motor Skills Disorders
Motor Development and Early Predictors of Psychomotor Outcomes in Preterm and Term Infants Assessed by MOS-R and Caregiver Questionnaire at 18 and 36 Months
This study examines how early motor behavior in infants relates to their later psychomotor development. Researchers will observe both preterm and full-term infants during the first months of life, using video-based assessments to…
- Conditions
- Neurodevelopmental Disorders, Motor Skills Disorders, Infant, Premature Development, Infant, Term Development
- Trial name
- NCT07296003
- Testing
- Vojta method
- Where
- 3 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Preterm Infant, Physical Therapy
Early Physical Therapy Intervention in Preterm Infants
The hypothesis of this study is that early physical therapy intervention, initiated during the NICU stay and up to 2 months corrected age, based on the family-centered model, could promote preterm infants motor development in…
- Conditions
- Preterm Infant, Physical Therapy, Early Intervention, NICU
- Trial name
- NCT03313427
- Testing
- Physical Therapy Early Intervention, Usual Care
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Preterm Infant, Feeding Behavior
A Cue-based Developmental Approach Toward the Preterm Infants During Feeding Transition Period
The coordination of sucking, swallowing, and breathing during the transition from gavage to oral feeding is a challenge for preterm infants.
- Conditions
- Preterm Infant, Feeding Behavior, Feeding Patterns
- Trial name
- NCT03755999
- Testing
- The premature infant oral motor intervention (PIOMI)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Anemia
Effect of Maternal Hemoglobin on Neurobehavioural Development of Late Preterm Neonates : A Cohort Study
The study entitled 'Effect of maternal hemoglobin on neurobehavioral development of late preterm neonates' was done with an objective to determine whether low maternal hemoglobin (<11gm/dl), in late preterm neonates(>34weeks but…
- Trial name
- NCT02840292
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Lady Hardinge Medical College
Perinatal Stroke
Baby Brain Recovery Study
This study will be a longitudinal multiple-visit observational study, done to identify possible bioindicators of recovery and repair of motor corticospinal pathways which may be targeted by future interventions in infants with…
- Trial name
- NCT05013736
- Testing
- Magnetic Resonance Imaging, Behavioral Assessments, Non invasive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Wisconsin, Madison
Achondroplasia
A Clinical Trial to Evaluate the Safety and Efficacy of BMN 111 in Infants and Young Children With Achondroplasia
Study 111-206 is a Phase 2 randomized, double-blind, placebo-controlled clinical trial of BMN 111 in infants and young children with a diagnosis of achondroplasia.
- Trial name
- NCT03583697
- Testing
- BMN 111
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 75 people
- Sponsor
- BioMarin Pharmaceutical
Infant, Premature
The Effect of Physical Therapy Intervention on Motor Performance in Bhutanese Preterm Infants
The purpose of this randomized controlled trial is to assess if physical therapy intervention works well to improve motor performance in Bhutanese preterm infants.The main question the study aims to answer is: Will physical…
- Trial name
- NCT06109350
- Testing
- Supporting play exploration and early developmental intervention(SPEEDI), Standard care
- Where
- Bhutan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- JDWNRH
Primary Congenital Glaucoma, Developmental Glaucoma
Ologen® Collagen Matrix in Patients With Primary Congenital Glaucoma Undergoing Trabeculectomy
To the best of Investigator knowledge, no studies to this date have compared the safety and efficacy of ologen® Collagen Matrix in Primary congenital glaucoma (PCG) patients undergoing trabeculectomy.
- Conditions
- Primary Congenital Glaucoma, Developmental Glaucoma, Infantile Glaucoma
- Trial name
- NCT03541551
- Testing
- CTT with ologen® Collagen Matrix, Trab Trab
- Where
- India
- Volunteers
- 44 people
- Sponsor
- L.V. Prasad Eye Institute