Clinical trials: Infant Developmental Assessment
Zika Virus
ZIKAlliance Children Cohort (ZIKAllianceCH)
The aim of this proposal is to evaluate the causal relationship between Zika virus (ZIKV) infections in pregnancy and congenital malformations.
- Trial name
- ZIKAllianceCH (NCT03393286)
- Where
- 10 sites in Bolivia, Brazil and 5 more
- Volunteers
- 1,554 people, healthy volunteers welcome
- Sponsor
- University of Heidelberg Medical Center
Language Development Disorders, Preterm Birth
Evaluation of an Early Support Programme in Orthophony
Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho)…
- Trial name
- PAPEV-ortho (NCT04384328)
- Testing
- Early Support Programme in Orthophony
- Where
- 4 sites in France
- Volunteers
- 76 people
- Sponsor
- Centre Hospitalier Sud Francilien
Birth Asphyxia, Neonatal Resuscitation
The Baby-Saver Kit: Clinical Testing of a Device for Neonatal Resuscitation With Intact Cord in Uganda
To examine the usability, safety and acceptability of the BabySaver kit: a novel device for neonatal resuscitation in a low-income region in Africa
- Conditions
- Birth Asphyxia, Neonatal Resuscitation, Maternal Distress
- Trial name
- BabySaver (NCT03885492)
- Where
- Uganda
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sanyu Africa Research Institute
Healthy
Followup of Infants Fed Non-routine Infant Formula
The purpose of this study is to compare physical development of infants fed one of three study formulas.
- Trial name
- NCT00665938
- Testing
- Infant formula
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Preterm Infants, Infant, Low Birth Weight
Effects of Early Yakson Touch and Kinesthetic Stimulation on the Development of High Risk Neonates
The role of physiotherapy interventions in treatment of high risk infants has not been established even after a number of studies.
- Trial name
- YTKS (NCT02815904)
- Testing
- Yakson touch, Conventional handling, Kinesthetic stimulation
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Asir John Samuel
Violence, Depression
A Pilot Evaluation of the Pregnant Moms' Empowerment Program
This project will use a longitudinal design with assessments at baseline (T1), post-treatment (T2), 3 month post-partum (T3), 1 year postpartum (T4) and 3.5-5 years postpartum to examine whether the PMEP improves participants'…
- Conditions
- Violence, Depression, Posttraumatic Stress Disorder, Parenting
- Trial name
- NCT05011825
- Testing
- Pregnant Moms' Empowerment Program
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Infant Development, Breastfeeding
The Effects of Massage Therapy on Term Neonates Development and on Maternal Bonding
This study collects data from 2 groups of mother- term neonate pairs at the Neonatal Department of Children Hospital II, Ho Chi Minh City (in group M: neonates are massaged by their mothers during the first 2 months after birth…
- Conditions
- Infant Development, Breastfeeding, Postnatal Depression
- Trial name
- NCT04285437
- Testing
- infant massage
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Autism Spectrum Disorder
Duration of Moment in Autism
This study investigates the temporal dynamics of perception and attention in children with Autism Spectrum Disorder (ASD), focusing on two key phenomena: the Temporal Integration Window (TIW) and the attentional blink.
- Trial name
- DOMA (NCT07384819)
- Testing
- Temporal Integration Window task, Attentional Blink task
- Where
- 2 sites in France
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Premature Infant, Risk Factors
Perinatal Risk Factors in Motor Development
The aim of this study is to analyze the effect of preterm gestational age, birth weight and perinatal risks factors on gross motor development of preterm infants.
- Conditions
- Premature Infant, Risk Factors, Motor Development of Premature Infants
- Trial name
- NCT07310459
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Universidad de Murcia
Image Evaluation
Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit
This study investigates a novel magnetic resonance imaging (MRI) system designed by GEHC for imaging viable neonate and infant populations.
- Trial name
- Firefly (NCT02232009)
- Testing
- 3.0 T Neonatal MRI Scanner
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- GE Healthcare
DSD, CHH
Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope
Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g.
- Trial name
- MiniNO (NCT05058781)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Motor Delay, Infant Development
Wearable Sensor Toolkit for Infant Motor Development
The purpose of this study is to develop and test a fully automated, wireless sensor-based toolkit for infants that can capture early indicators (0-3 months) of motor deficits during activities of daily life and track motor…
- Conditions
- Motor Delay, Infant Development, Motor Development of Premature Infants, Motor Coordination or Function; Developmental Disorder
- Trial name
- NCT07866495
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Pregnancy, Premature Birth
Development of a Nationally Scalable Model of Group Prenatal Care to Improve Birth Outcomes: "Expect With Me"
This study addresses the intractable challenges of adverse birth outcomes, including preterm delivery and low birthweight, by proposing the development, implementation and evaluation of a model of group prenatal care that could…
- Conditions
- Pregnancy, Premature Birth, Infant, Low Birth Weight, Postpartum Period
- Trial name
- NCT02169024
- Testing
- Expect With Me group prenatal care, Standard individual prenatal care
- Where
- 2 sites in United States
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- Yale University
Cerebral Palsy, Infant, Premature, Diseases
Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements
High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems.
- Conditions
- Cerebral Palsy, Infant, Premature, Diseases, Infant Development, Neurologic Disorder
- Trial name
- highrisk (NCT05217186)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Kahramanmaras Sutcu Imam University
High-risk Infants
Telematic Support in Early Intervention on Infants At Risk of Neurodevelopmental Delays
The purpose of this study is to evaluate the effects of early intervention support sessions via video conferencing as an adjuvant option to motor development on infants at risk of neurodevelopmental delays or disorders.
- Trial name
- BBL-ATOP (NCT06608576)
- Testing
- Face-to-face standard treatment, Telematic Support
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Granada
HIV Infections, HIV/AIDS
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
The purpose of this early Phase 2 comparison trial is to evaluate the impact of community health worker (CHW) home visitors on pregnant women and their children in a rural setting in the rural Eastern Cape of South Africa.
- Conditions
- HIV Infections, HIV/AIDS, Depression, Depressive Symptoms
- Trial name
- NCT03517878
- Testing
- Comprehensive CHW Program
- Where
- 2 sites in South Africa
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Apgar Score, Motor Coordination or Function; Developmental Disorder
Effect of Tobacco Use on the Health of the Newborn up to 24 Months.
There is scientific evidence suggesting that tobacco use during pregnancy is associated with several adverse effects in newborns, including low birth weight, respiratory complications, severe neonatal morbidity, perinatal death…
- Conditions
- Apgar Score, Motor Coordination or Function; Developmental Disorder, Lactation, Weight Control
- Trial name
- ETUHeNewBorn (NCT07427706)
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Healthy Participants
Assessment of Neurofilaments Levels in Premature Newborns: Study of Their Early Development
This is a prospective observational study aiming to establish reference values of neurofilaments in late preterm newborns (34-37 weeks of gestation) and to evaluate their early postnatal evolution.
- Trial name
- NCT07159555
- Testing
- Blood sampling for neurofilament analysis
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Preterm Birth, Development Delay
Evaluation of Digital Follow up of Preterm Infants
The aim is to study how a digital follow up tool can identify the preterm born children and their families who need further support or clinical interventions
- Conditions
- Preterm Birth, Development Delay, Sensory Disorder, Growth Disorders
- Trial name
- ePIPARI (NCT05238168)
- Testing
- ePIPARI digital follow up tool
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Turku University Hospital