Clinical trials: Infarction
Myocardial Infarction
Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness
is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients
- Trial name
- NCT03308539
- Testing
- echocardiography and cardiac magnetic resonance
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Osama Fekry
ST Elevation Myocardial Infarction
Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI
This study is aimed to investigate if the bivaliruding with prolonged full dose infusion after PCI is superior to heparin alone in reducing 30-day mortality or major bleeding for patients with STEMI treated with emergency PCI.
- Trial name
- BRIGHT-4 (NCT03822975)
- Testing
- Bivalirudin, unfractionated Heparin
- Where
- 85 sites in China
- Volunteers
- 6,016 people
- Sponsor
- Shenyang Northern Hospital
Cardiovascular Diseases, Hypertension
Survival After Myocardial Infarction in A Biethnic Texas Community (Corpus Christi Heart Project)
To determine the natural history of coronary heart disease in the biethnic community of Corpus Christi, Texas.
- Conditions
- Cardiovascular Diseases, Hypertension, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005198
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Myocardial Infarction
Validation of a High-risk Versus Low-risk Referral Model in Suspected Acute Coronary Syndrome
In Emergency Departments patients admitted with chest pain may suffer from non-significant to lifethreatening conditions. The aim of the present study is to develop and validate a referral model in chest pain patients which…
- Trial name
- NCT01747421
- Where
- Denmark
- Volunteers
- 495 people
- Sponsor
- University of Southern Denmark
Cardiovascular Diseases, Heart Diseases
Compliance in the Physicians' Health Study
To evaluate the relationships of compliance in taking aspirin or aspirin placebo with the risk of major cardiovascular endpoints, using data collected in the Physicians' Health Study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005404
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sickle Cell Disease, Stroke
Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
This is a pilot study of hydroxyurea versus placebo to reduce central nervous system complications (abnormally fast blood flow to the brain, silent cerebral infarct or stroke) in young children with sickle cell disease.
- Trial name
- HUPrevent (NCT01389024)
- Testing
- Hydroxyurea
- Where
- 5 sites in United States
- Volunteers
- 28 people
- Sponsor
- Johns Hopkins University
Acute Myocardial Infarction
Mortality Analysis of ST Elevation Myocardial Infarction (STEMI) Patients in Belgium
The purpose of this observational study is to assess predictors of in-hospital mortality in patients with acute myocardial infarction admitted to Belgian hospitals.
- Trial name
- NCT00727623
- Where
- Belgium
- Volunteers
- 20,000 people
- Sponsor
- Universiteit Antwerpen
Myocardial Infarction, Dyslipidemias
Research on Burden of Disease for Patients With Myocardial Infarction Combining Dyslipidemia in China
This study is medical record review and questionnaire survey on the economic burden on Chinese patients with myocardial infarction accompanied by dyslipidemia in a real-world environment.
- Trial name
- NCT03691246
- Where
- 5 sites in China
- Volunteers
- 900 people
- Sponsor
- China Cardiovascular Association
Sickle Cell Anemia, Stroke
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial
The goal of this study is to determine the effectiveness of blood transfusion therapy for prevention of silent cerebral infarct (stroke) in children with sickle cell anemia.
- Trial name
- SIT (NCT00072761)
- Testing
- transfusion therapy
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Washington University School of Medicine
Myocardial Infarction
Post- Myocardial Infarction Arterial Wall Improvement by Low-dose Fluvastatin and Valsartan
The concept of improving arterial wall characteristics by treatment with a very low-dose combination of fluvastatin and valsartan (low-flu/val) in stable, post-myocardial infarction (MI) patients was tested.
- Trial name
- NCT03309618
- Testing
- low-dose combination of fluvastatin (10 mg) and valsartan (20 mg) (low-flu/val)
- Where
- Slovenia
- Volunteers
- 36 people
- Sponsor
- University Medical Centre Ljubljana
TBI (Traumatic Brain Injury), Stroke Acute
The Multicenter Italian INCEPT (INfarto CErebrale Post-Traumatico) Study
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide (Ghajar, 2000). With an estimated annual incidence of up to 500 per 100,000 population and more than 200 hospital admissions per 100,000 admissions…
- Trial name
- NCT02430324
- Testing
- posttraumatic cerebral infarction
- Where
- Italy
- Volunteers
- 143 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Acute Myocardial Infarction
Association Between Active Transport and Acute Myocardial Infarction
This study aims to investigate the association between active transport and the incidence of acute myocardial infarction in England.
- Trial name
- NCT03032289
- Testing
- Active Transport
- Where
- United Kingdom
- Volunteers
- 100,482 people
- Sponsor
- University of Leeds
Acute Myocardial Infarction
Comparison of Drug Eluting and Bare Metal Stents With or Without Abciximab in ST Elevation Myocardial Infarction
The DEBATER study is designed to determine the superiority of abciximab over no abciximab and to determine the superiority of drug eluting stents over bare metal stents in patients with acute myocardial infarction who undergo…
- Trial name
- DEBATER (NCT00986050)
- Testing
- Abciximab, bare metal stent prokinetic, chrono, skylor or bluemedical, drug eluting stent (sirolimus eluting) - CYPHER stent
- Where
- Netherlands
- Volunteers
- 907 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Cardiogenic Shock, Cardiac Arrest
China Extracorporeal Life Support Registry
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective cardiac and respiratory support to patients with lungs and/or heart failure.
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress Syndrome
- Trial name
- NCT04158479
- Testing
- ECMO
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Beijing Anzhen Hospital
Heart Attack, Stroke
ACS Registry - A Non-interventional Study to Estimate the Rates of Outcomes in ACS Patients in Moscow
Cardiovascular diseases (CVD) are currently the leading cause of death in industrialized countries and are expected to become the leading cause of death in emerging countries by 20201.
- Conditions
- Heart Attack, Stroke, Cardiovascular Death
- Trial name
- NCT03654157
- Where
- 27 sites in Russia
- Volunteers
- 1,576 people
- Sponsor
- AstraZeneca
Amyotrophic Lateral Sclerosis, Brain Stem Stroke
Real World Testing of a Brain-Computer Interface
The goal of this project is to test a new AAC-BCI device comparing gel and dry electrode headgear used for communication while providing clinical care.
- Conditions
- Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury
- Trial name
- NCT04026581
- Testing
- Speech generating device (SGD) evaluation including BCI access, Training and treatment
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Stroke, Cerebrovascular Diseases
An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases
In this protocol, the investigators present methods and preliminary results from the PLATFORM-CVD Study, an EHR-based multicenter cohort.
- Conditions
- Stroke, Cerebrovascular Diseases, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- PLATFORM-CVD (NCT04775836)
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Cardiovascular Diseases, Heart Diseases
Worcester Heart Attack Community Surveillance Study
To examine time trends in the incidence rates of acute myocardial infarction and out-of-hospital coronary heart disease deaths as well as changes in the in-hospital and long-term case-fatality rates of acute myocardial infarction…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005196
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome
The Harefield Acute Myocardial Infarction Cohort
In this project the investigator's plan to collect blood during a patient's routine angiogram procedure which they will have due to having suffered a heart attack.
- Trial name
- HEART - ACS (NCT04218344)
- Testing
- 60mls of blood donated for research analysis
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Heart Failure, Myocardial Infarction
Echocardiographic Examination Performed by Nurses in Cardiac Intensive Care Unit
The purpose of this study is: To study the clinical usefulness of nurse-performed ultrasound and echocardiographic examinations in a cardiac intensive care unit.
- Conditions
- Heart Failure, Myocardial Infarction, Pleural Effusion
- Trial name
- NCT00886548
- Testing
- Ultrasound performed
- Where
- Norway
- Sponsor
- Helse Nord-Trøndelag HF