Clinical trials: Infertile Patients
Infertility
Does a Brief Intervention Decrease Patient Drop Out Rates?
The goal of this study is to determine a) if a follow-up email to selected patients who had an initial consult with an infertility specialist, but did not return for a second visit, would change return to care behavior and b) why…
- Trial name
- NCT04803045
- Testing
- Follow up email
- Where
- United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Cryopreservation
Testicular Tissue Cryopreservation for Fertility Preservation in Male Patients Facing Infertility-causing Diseases or Treatment Regimens
Many chemotherapy and radiation-containing regimens for cancer or prior to bone marrow transplantation can cause sterility in children and young adults.
- Trial name
- NCT02687880
- Testing
- Testicular biopsy
- Sponsor
- University of Colorado, Denver
Phimosis, Foreskin; Tightness
Safety and Efficacy of the Sterile Single-use Circular Stapling Device CIRCCURER II (Jiangxi Langhe Medical Instrument Co., Ltd., Guangzhou, China)
Evaluation of the safety and efficacy of the sterile single-use circular stapling device CIRCCURER II (Jiangxi Langhe Medical Instrument Co., Ltd., Guangzhou, China) in comparison with circumcision in adults patients with…
- Conditions
- Phimosis, Foreskin; Tightness, Redundant Prepuce
- Trial name
- CiCi-2021 (NCT04902898)
- Testing
- Circumcision in adults using sterile single-use circular stapling device, Circumcision in adults
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Infertility, Miscarriage
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689428
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Polycystic Ovary Syndrome, Infertility
New Application of Sequential in Vitro Muturation System for Infertility Patients With Polycystic Ovary Syndrome
Oocyte in vitro maturation (IVM) is an artificial reproductive technologies (ART) in which cumulus-oocyte complex (COC) are collected at the immature germinal vesicle (GV) stage from unstimulated or FSH-primed ovaries and matured…
- Trial name
- NCT03773263
- Testing
- sequential IVM system, intracytoplasmic sperm injection (ICSI), Thawed embryo transfer (TET)
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Fertility Preservation, Lymphoma
AMH as a Predictor of Infertility Risk in Children With Cancer (CHANCE)
While most of the children spontaneously recover menstruation or experienced normal puberty after chemotherapy, their ovarian reserve may be impaired by treatment inducing future infertility.
- Conditions
- Fertility Preservation, Lymphoma, Pediatrics Cancer, Gonadotropin-releasing Hormone Agonist
- Trial name
- CHANCE (NCT02595255)
- Testing
- No intervention
- Where
- 8 sites in Belgium, France
- Volunteers
- 275 people
- Sponsor
- Erasme University Hospital
Steroid Refractory Acute Graft Versus Host Disease
Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease
This is a single-arm, open-label, multicenter study of the efficacy of UVADEX® (methoxsalen) Sterile Solution in conjunction with THERAKOS® CELLEX® Photopheresis Systems (ECP) in pediatric participants with steroid-refractory…
- Trial name
- NCT02524847
- Testing
- Methoxsalen, Extracorporeal Photopheresis (ECP)
- Where
- 32 sites in United States, Austria and 6 more
- Volunteers
- 29 people
- Sponsor
- Therakos, Inc., a Mallinckrodt Company
Infertility
Anti-Mullerian Hormone (AMH) and Antral Follicle Count as Markers of Ovarian Reserve- Prospective Followup of Young Cancer Patients
young female cancer patients have improving chances of survival. the main risk is a chronic damage to their ovarian reserve. This may lead to future infertility.
- Trial name
- Ovrescancer (NCT00930501)
- Testing
- blood tests
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Infertility, Female
Sildenafil and Outcome of IVF/ICSI Cycles
Adequate growth of the endometrium is crucial for implantation. Accordingly, the pregnancy success rate of patients with a thin endometrium is low.
- Trial name
- NCT03192709
- Testing
- Sildenafil vaginal suppositories
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling
THALASSEMIA MAJOR
Reproductive Capacity and Iron Burden in Thalassemia
The improved long-term survival of thalassemia major (TM) patients has resulted in increased focus on the ability to preserve fertility.
- Trial name
- Fertility thal (NCT02308904)
- Testing
- Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary MRI
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Cell- and Tissue-Based Therapy
Amnion Bilayer and Stem Cell Combination Therapy on Thin Endometrium Infertile Patients
Severe infections or trauma to the endometrial lining causes permanent scars that disrupt the menstrual cycle and lead to conceive failure.
- Trial name
- NCT04676269
- Testing
- Amnion only, Amnion - endometrium cells, Amnion - amnion epithelial cells
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Infertility, Tuberculosis
The Effect of Latent Tuberculosis Infection on the Pregnancy Outcome of IVF-ET
This study evaluate the effect of latent infection of tuberculosis on the pregnancy outcome of IVF-ET in infertile patients with radiographic lesions suggesting old healed tuberculosis
- Trial name
- NCT04443283
- Testing
- No intervention
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Infertility
Endometrial Local Injury and Implantation Failure
The purpose of this study is to evaluate the influence of endometrial biopsy on increasing implantation rate in patients with recurrent implantation failures, 93 women with at least two implantation failures were evaluated.
- Trial name
- NCT00837733
- Testing
- Endometrial biopsy
- Where
- Iran
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Infertility,Female
Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response
A randomized, controlled, pilot study, for Patients ≥ 35 years and < 40 years old with sufficient ovarian reserve parameters (AFC≥ 5), but showed an unexpected poor or suboptimal ovarian response(defined as ≤ 9 retrieved oocytes…
- Trial name
- NCT04178135
- Testing
- rLH
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility
Comparison of Two Embryo Transfer Catheters in Patients Undergoing in Vitro Fertilization and Embryo Transfer
In-vitro fertilization (IVF) treatment involves development of multiple follicles following ovarian stimulation, oocyte retrieval and embryo transfer (ET). ET is the final and most crucial step of IVF treatment.
- Trial name
- NCT02024880
- Testing
- Protective catheter group, Conventional catheter group
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The University of Hong Kong
Infertility
Group Preconception Care for Fertility Patients
Group Preconception Care for Fertility Patients aims to translate the well-established group prenatal care model to preconception care to improve pregnancy and neonatal outcomes.
- Trial name
- NCT05924464
- Testing
- Group Preconception Care
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Pennsylvania
Infertility
A Retrospective Study in Chinese Good Prognosis Patients Undergoing Assisted Reproductive Technology (ART) Treatment
This is a multicenter retrospective study in good prognosis Chinese patients. Data will be collected from infertile women who underwent first in vitro fertilization (IVF)/intra cytoplasmic sperm injection (ICSI) using a…
- Trial name
- FASSION (NCT02889380)
- Testing
- No Intervention
- Where
- 4 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Influence of Ethnical Differences on the Egg Cell Collected in Patients Undergoing Fertility Treatment
Investigators wants to analyze the differences considering the country of origin, ethnicity, characteristics, reproductive history and habits of participants undergoing in vitro fertilization (IVF) / intracytoplasmic sperm…
- Trial name
- NCT03927417
- Where
- United Arab Emirates
- Volunteers
- 1,117 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC