Clinical trials: Infertile Patients
Asthenozoospermia
Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers
Although several studies have considered the relationship between infertility and semen super oxide radical scavengers levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on superoxide…
- Trial name
- NCT02217189
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Babylon University
Male Infertility, Heart Valve Disease
Warfarin Effects on Male Fertility After Cardiac Surgery
Young male patients undergoing cardiac surgery may require oral anticoagulation with warfarin either lifelong, such as after mechanical valve replacement, or for a limited postoperative period, for example following valve repair…
- Trial name
- NCT07330869
- Testing
- Semen analysis, sperm DNA fragmentation and hormonal evaluation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Città di Lecce Hospital, GVM Care & Research
Azoospermia, Nonobstructive
TESE and Non Obstructive Azoospermia
Azoospermia is complete absence of sperm in the ejaculate. It accounts for 10-15% of male infertility cases. It is classified as obstructive and non-obstructive azoospermia (NOA). NOA constitutes 60% of all cases of azoospermia.
- Trial name
- NCT03146260
- Testing
- Conventional TESE, Microdissection TESE
- Volunteers
- 148 people
- Sponsor
- Assiut University
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Urothelial Cancer of Renal Pelvis, Urothelial Carcinoma Ureter
Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma
There is a high rate of intravesical (bladder) recurrence following extirpative surgery for upper tract urothelial carcinoma. There is no single established standard of care for prevention of intravesical recurrence; however, one…
- Trial name
- NCT04865939
- Testing
- sterile water irrigation, Gemcitabine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Texas Southwestern Medical Center
Fertility Disorders, Infertility (IVF Patients)
The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women
This randomized controlled trial aimed to determine whether a mindfulness-based lifestyle support program would improve quality of life, lifestyle, mindfulness, attention and meditation level and treatment outcomes in women…
- Trial name
- NCT06799507
- Testing
- Interventions Based on Mindfulness, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Infertility, Poor Responder to IVF Treatment
Study of Dehydroepiandrosterone Treatment for Poor Responders in In Vitro Fertilization Patients
The aim of this study is to show solid evidences of the efficacy of DHEA in improving the success rates of in-vitro fertilization (IVF) patients facing poor ovarian reserve.
- Trial name
- NCT01535872
- Testing
- Dehydroepiandrosterone
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- KK Women's and Children's Hospital
Infertility
Aurora Test for ART Donor Patients (AURORA-Donor)
This is a randomized observational study. The main aim is to determine potential oocyte competence predictive mRNA expression profiles in the cumulus cells isolated form individual oocytes.
- Trial name
- NCT06280677
- Testing
- AURORA-Donor
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fertiga, Belgium
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in IVF Patients
In assisted reproductive treatment (ART), it is necessary to follow closely the stimulation cycles of patients undergoing these treatments in order to monitor the number and size of developing follicles.
- Trial name
- SALIVA_MINT (NCT05184777)
- Testing
- Determination of progesterone and oestradiol
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Female
hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility
To explore the therapeutic effect and safety of human umbilical cord mesenchymal stem cells on thin endometrial infertility and to explore whether human umbilical cord mesenchymal stem cells using collagen as the carrier can…
- Trial name
- NCT05495711
- Testing
- human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Infertile Patients
the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval.
- Trial name
- NCT06937645
- Testing
- Hyaluronic Acid (HA), platlet rich plasma (PRP)
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Nahrain University
Infertility
Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
The purpose of study is to assess the efficacy of add-on estrogen pretreatment in GnRH antagonist protocol on oocyte retrieval as compared with GnRH antagonist protocol for patients with poor ovarian response Add-on estrogen…
- Trial name
- NCT03300518
- Testing
- Follitropin Beta;MSD, Ganirelix, hCG
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility
The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients
After hCG trigger a large amount of exogenous progesterone is used for luteal phase support in many countries until 10th week of gestation.
- Trial name
- GnRHa trigger (NCT01980680)
- Testing
- hCG, Progesterone and Estradiol
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Peter Humaidan
Women Infertility
G-CSF Administration in IVF in a Preferable Preceptive Endometrium Score
This is a controlled preminary trial intended to increase the implantation rate of IVF cycles, by using more than one known procedure, endometrial scratching, evaluating the status of the adhesive factors as αVβ3 integrin…
- Trial name
- NCT03163862
- Testing
- Endometrial scratch, G-CSF administration, Saline Solution
- Volunteers
- 100 people
- Sponsor
- Istishari Arab Hospital
Infertility, Preimplantation Genetic Screening
Cumulative Live Birth Rates in Patients With Repeated Implantation Failure (RIF) Undergoing Preimplantation Genetic Screening (PGS )
This is a single centre retrospective study in repeated implantation failure patients: < 39 years old, at least 4 D3 good quality embryos or 2 good quality blastocysts transferred without implantation, absence of known causes of…
- Trial name
- NCT03001648
- Testing
- PGS (Preimplantation Genetic Screening) with trophectoderm biopsy
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundacion Dexeus
Infertility
Ovarian Stem Cells From Women With Ovarian Insufficiency
Background: Primary ovarian insufficiency (POI) is a condition that affects ovary function. It means that the ovaries are not able to function at a level appropriate for a woman's age.
- Trial name
- NCT01702935
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility,Female
Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response
A randomized, controlled, pilot study, for Patients ≥ 35 years and < 40 years old with sufficient ovarian reserve parameters (AFC≥ 5), but showed an unexpected poor or suboptimal ovarian response(defined as ≤ 9 retrieved oocytes…
- Trial name
- NCT04178135
- Testing
- rLH
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Male Infertility, Oligozoospermia
Probiotics on Sperm Quality in Male Infertility Patients
This randomized, placebo-controlled pilot study aims to evaluate the effects of probiotic supplementation on sperm quality in male patients diagnosed with infertility.
- Conditions
- Male Infertility, Oligozoospermia, Asthenozoospermia, Teratozoospermia
- Trial name
- NCT07345455
- Testing
- Probiotics
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Mackay Memorial Hospital
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Cutaneous T Cell Lymphoma, Mycosis Fungoides
Photopheresis as an Interventional Therapy for the Treatment of CTCL (Cutaneous T-Cell Lymphoma, Mycosis Fungoides) Stage 1A, 1B, 2A
The study objective is to demonstrate that the UVADEX® Sterile Solution formulation of methoxsalen used in conjunction with the UVAR XTS Photopheresis System can have a clinical effect on the skin manifestations of CTCL (mycosis…
- Trial name
- NCT00221039
- Testing
- Methoxsalen+ECP
- Where
- 7 sites in United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center