Clinical trials: Inflammation Function
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Healthy Volunteers, Abnormal Phagocyte Function
Inflammatory Responses in Normal Volunteers and Patients With Abnormal Immune Responses
This study will investigate the inflammatory response. People with abnormal regulation of inflammation and immune defects often have an exaggerated or depressed inflammatory response that results in poor healing of recurrent…
- Trial name
- NCT00001257
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Bronchiolitis Obliterans
Lung Function, LCI, Bronchial Inflammation and Epigenetics of Patients With BO
Bronchiolitis obliterans is a chronic disease in which a persistent inflammatory process leads to obliteration of the small airways.
- Trial name
- FRABO-03 (NCT02627833)
- Testing
- observation
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Obesity, Stress
Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain
About 15 to 20 percent of individuals living in the United States have chronic abdominal pain, often of unknown origin, which is often difficult to diagnose and treat.
- Conditions
- Obesity, Stress, Irritable Bowel Syndrome, Women
- Trial name
- NCT00824941
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Neonatal Sepsis, Markers
Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis
1. To assess myocardial function in neonates with sepsis using tissue doppler echocardiography. 2. To assess sepsis induced cardiac dysfunction. 3.
- Trial name
- NCT07572916
- Testing
- cardiac troponin, and blood culture
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Transplant Failure and Rejection, Inflammation
The Effect of Biomarkers of Inflammation on Graft Function in Kidney Transplantation
The aim of the study was to investigate the relationship of inflammation markers with postoperative graft function and mortality in patients undergoing kidney transplantation.
- Trial name
- NCT05753488
- Testing
- graft function
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Asthma
Airflow Obstruction and Biomarkers of Airway Inflammation During and Following Acute Exacerbations of Childhood Asthma
This study is a longitudinal single-center pilot study designed to describe changes in lung function and levels of noninvasive biomarkers of airway inflammation in children ages 6-18 years over two months following…
- Trial name
- NCT01227070
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Diabetes Mellitus, Insulin-Dependent, Hypercholesterolemia
Statins in Children With Type 1 Diabetes and Hypercholesterolemia
Children with type1 diabetes (T1DM) have increased risk for cardiovascular disease (CVD) due to chronic increase in the blood sugars and inflammation.
- Trial name
- NCT01236365
- Testing
- Atorvastatin
- Where
- 5 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Gingival Inflammation
Evaluation of Anti Bacterial Effect of Titanium Dioxide Nanoparticles on Baseplates of Twin Block
Background The objective of this study was to evaluate the antibacterial effect of Titanium dioxide nanoparticles incorporated into the acrylic baseplates of maxillary part of twin block appliances in orthodontic patients during…
- Trial name
- NCT06051487
- Testing
- titanium dioxide nanoparticles in test group
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Allergic Conjunctivitis
The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis
A double-blind study to evaluate the role of vitamin D in corneal epithelial barrier function, ocular microbiome, ocular inflammation, and visual acuity of children with allergic conjunctivitis.
- Trial name
- NCT05839938
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Obesity, Asthma
Obesity-asthma Endophenotype and Diaphragm Mobility in Adolescence
Obesity and asthma share changes that may begin in the fetal development phase. The endophenotype obesity-asthma presents as main characteristic a pattern of inflammatory response different from the habitual Th2 profile of…
- Trial name
- NCT03029936
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Childhood Obesity, Inflammation
CASH- Children Active to Stay Healthy
The purpose of this study is to examine the effects of high intensity interval exercise (HIIE) on inflammation and endothelial dysfunction found in children with obesity.
- Trial name
- CASH (NCT01821313)
- Testing
- Moderate exercise, High Intensity Interval Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Healthy, Healthy Nutrition
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B.
- Trial name
- BEGIN (NCT06452199)
- Testing
- B. infantis
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers
Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents
Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as…
- Conditions
- Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers, Inflammation
- Trial name
- NCT07125001
- Testing
- Ataulfo mango
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
IBS - Irritable Bowel Syndrome, Ulcerative Colitis
The IMAGINE-SPOR CIHR Chronic Disease Network
The IMAGINE Cohort Study will identify and recruit a cohort of 8000 patients with IBS, IBD and healthy controls (2000 of each) who will be assessed in terms of their psychological status, dietary intake, gut microbiome…
- Conditions
- IBS - Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease, Healthy
- Trial name
- IMAGINE (NCT03131414)
- Testing
- Diet, Gastrointestinal microbiome
- Where
- Canada
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes
A CFit Study - Baseline
A great medical success is the increase in the median survival age associated with cystic fibrosis (CF). However, this success has led to a new era of research with the aim to maximise the quality of life (QoL) of the aging CF…
- Trial name
- NCT03234387
- Testing
- No intervention - only assessments.
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth