Clinical trials: Informed Consent
Breast Cancer
Multimedia-assisted Informed Consent Procedure for Patients Undergoing Mastectomy and Implant-based Reconstruction
Breast reconstruction is a women's right with positive psychological effects and it is an integral part of breast cancer treatment and care.
- Trial name
- NCT06541223
- Testing
- Standard informed consent procedure, Multimedia video
- Where
- Italy
- Volunteers
- 265 people
- Sponsor
- European Institute of Oncology
Stroke, Stroke (CVA) or Transient Ischemic Attack
Optimized Recruitment to Drive Equitable Research in Stroke, Empowering Decision-making (ORDERed)
Stroke is a major health issue, especially for women, who are more likely than men to have worse outcomes and lower quality of life after a stroke.
- Trial name
- ORDERed (NCT07576647)
- Testing
- Supported, women-centred and aphasia-friendly recruitment process (ORDERed), Traditional recruitment processes (TRADITIONAL)
- Where
- 3 sites in Canada
- Volunteers
- 1,600 people
- Sponsor
- McMaster University
Informed Consent
Enhancing Quality of Informed Consent (EQUIC-DP) Developmental Phase
Patients in 'parent' cooperative studies projects are interviewed about their experiences in the informed consent process.
- Trial name
- NCT00032552
- Where
- 18 sites in United States
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Osteosarcoma, Ewing's Sarcoma
Informed Consent in Pediatric Cancer Trials
Background: Informed consent is the process by which prospective participants in clinical trials learn about clinical research in order to decide whether they want to enroll in the study.
- Conditions
- Osteosarcoma, Ewing's Sarcoma, Neuroblastoma, Brain Tumors
- Trial name
- NCT00923650
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Standard Training, Online Training
Ethical, Legal, and Social Issues Substudy in Relation to the GTEx Project
The Ethical, Legal and Social Issues Substudy in relation to the Genotype Tissue Expression Project (GTEx) aims to describe tissue requesters' approach to discussions about donation to GTEx and to assess the determinants of…
- Trial name
- ELSI (NCT02887339)
- Testing
- Training Website, Control
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Temple University
HIV Infections
Consent for Use of Stored Patient Specimens for Future Testing
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
- Trial name
- NCT00031408
- Where
- 63 sites in United States, Puerto Rico
- Volunteers
- 17,444 people, healthy volunteers welcome
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Fever, Malaria
Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children
The main objective is to compare the safety and efficacy of 4 artemisinin-based combinations (ACT) [amodiaquine-artesunate (AQ+AS), dihydroartemisinin-piperaquine (DHAPQ), artemether-lumefantrine (AL) and chlorproguanil/dapsone…
- Trial name
- NCT00393679
- Testing
- amodiaquine-artesunate (ASAQ), dihydroartemisinin-piperaquine (DHAPQ), artemether-lumefantrine (AL)
- Where
- 8 sites in Burkina Faso, Gabon and 5 more
- Volunteers
- 4,112 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Depression
Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study
The aim of the present study is to prospectively assess the anti-depressant effectiveness of reboxetine in children and adolescents, as compared with fluoxetine, in a randomized controlled open-label trial.
- Trial name
- NCT00426946
- Testing
- Reboxetine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Geha Mental Health Center
Hysteroscopy Surgery, Informed Consent
Assessing the Impact of a Patient Education Platform to Augment the Informed Consent Process for Obstetrics and Gynecology Procedures
Over the past few decades, there has been a shift in the informed consent process, whereby the focus is centered on patient comprehension, preparedness and satisfaction.
- Trial name
- NCT04614688
- Testing
- Patient Education Platform
- Volunteers
- 78 people
- Sponsor
- Unity Health Toronto
Rare Disorders
Implementing Dynamic Consent for Rare Disease Patients
The study aims to test on a cohort of rare patients a digital innovative tool to support patients/parents in the informed consent and assent process and to keep up-to-date a lawful informed and dynamic consent and to use samples…
- Trial name
- ConsDinamico (NCT06656247)
- Testing
- Online consenting
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Fragile X Syndrome (FXS)
Decisional Capacity and Informed Consent in Fragile X Syndrome
The Decisional Capacity and Informed Consent in Fragile X Syndrome (FXS) project is for the Eunice Kennedy Shriver National Institute of Child Health \& Human Development, 1R01HD071987-01A1, and will provide the first…
- Trial name
- NCT02465931
- Testing
- Paper and Pencil Informed Consent, Digital Informed Consent Tool
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- RTI International
Adolescents
Parental Permission and Adolescent Assent and Decision-Making in Clinical Research
This study will evaluate how adolescents enrolled in clinical research and their parents: Understood the study information presented before they agreed to participate Made decisions about enrolling in the study Experienced the…
- Trial name
- NCT00571311
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alzheimer's Disease, Aging
Memory Aid for Informed Consent in Alzheimer's Research
The purpose of this trial is to test whether a memory and organizational aid in the form of a document that summarizes and simplifies a study's key points can improve the decision-making abilities and competency of mild to early…
- Trial name
- NCT00105612
- Testing
- Memory and Organizational Aid, Standard Informed Consent Process
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Institute on Aging (NIA)
Informed Consent Process
A Parental Educational Intervention to Facilitate Informed Consent for Pediatric Procedural Sedation in the Emergency Department
This study is planning to develop the computed-assisted information program and determine whether the computed-assisted information program are superior to routine discussion for informing parents in the emergency department (ED)…
- Trial name
- NCT01850329
- Testing
- computed-assisted information program
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
HIV Infections
Influences on HIV Infected Subjects' Willingness to Participate in Research and Ability to Give Informed Consent
This protocol seeks to better understand the various factors which influence an HIV infected individual's decision to participate in clinical research, and especially how the offer of payment influences the decision to…
- Trial name
- NCT00001717
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cataract, Surgery
Video-assisted Informed Consent for Cataract Surgery
The investigators will investigate whether video-assisted informed consent is superior to routine discussion for cataract patients about risks, benefits and alternatives to receiving phacoemulsification cataract extract and…
- Trial name
- NCT02185807
- Testing
- video-assisted group, control group
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangzhou First People's Hospital
Improving Informed Consent Process
Use of a Multimedia Presentation for Informed Consent
This is a prospective cohort study in which the standard verbal informed consent process for ketamine sedation is compared to a multimedia informed consent process.
- Trial name
- NCT01955070
- Testing
- Multimedia Presentation for Ketamine sedation
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Nationwide Children's Hospital
Informed Consent
Patients' Comprehension and Internalization of Operative Consent Form
This is a prospective pilot study conducted within otolaryngology (ENT) clinics in a tertiary hospital between July and December 2016.
- Trial name
- NCT04627597
- Volunteers
- 22 people
- Sponsor
- Singapore General Hospital
Recurrent Diffuse Pontine Gliomas
Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma
This is a phase 2, single-arm, multi-center study, with a safety review component, designed to evaluate the efficacy and safety of nimotuzumab in approximately 44 patients with recurrent diffuse intrinsic pontine glioma (DIPG)…
- Trial name
- NCT00600054
- Testing
- nimotuzumab (anti EGFR humanized monoclonal antibody)
- Where
- 13 sites in United States, Canada and 1 more
- Volunteers
- 44 people
- Sponsor
- YM BioSciences
Quality Improvement, Informed Consent
Quality Improvement Study on Operative Consent Forms
A Quality Improvement Project was undertaken to improve the completion of operative consent forms within a UK hospital plastic surgery department.
- Trial name
- NCT04493866
- Testing
- Messages to departmental employees to improve quality of consent form completion
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust