Clinical trials: Inhibitory Control
Obsessive Compulsive Disorder (OCD)
NAC for Treatment-Resistant OCD and Other Related Disorders
This is a randomized, double-blind, placebo-controlled study investigating N-acetylcysteine (NAC) as an augmentation therapy for individuals with treatment-resistant obsessive-compulsive disorder (TR-OCD), studied within a…
- Trial name
- NCT06956157
- Testing
- N-Acetylcysteine Tablets
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Motor Development, Balance
Balance-Cognitive-Strength Training for Balance, Inhibitory Control, and Gait in Preschool Children
This randomized controlled study evaluated whether an 8-week balance-cognitive-strength training program improved balance ability, inhibitory control, and gait performance in preschool children aged 3 to 6 years.
- Conditions
- Motor Development, Balance, Healthy Children, Gait
- Trial name
- BCS-Preschool (NCT07689474)
- Testing
- Balance-Cognitive-Strength Training
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Executive Functions (EF)
Boosting Executive Function With Real-class Exercise
The goal of this study is to examine the effects of acute pre-class physical exercise on executive function in real classroom settings.
- Trial name
- NCT07231536
- Testing
- Mentally active sitting, 5-minute physical exercise, 10-minute physical exercise
- Where
- China
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Shenzhen University
Major Depressive Disorder, Major Depressive Disorder, Recurrent
Glutamate Probes in Adolescent Depression
The purpose of this study is to learn if measures of brain chemicals from a brain scan called Magnetic Resonance Imaging and Spectroscopy (MRI/MRS) and brain activity (known as cortical excitability and inhibition) collected by…
- Conditions
- Major Depressive Disorder, Major Depressive Disorder, Recurrent, Major Depressive Disorder, Remitted
- Trial name
- GPII (NCT02307617)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight and Obesity
Inhibitory Control and Pediatric Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the Kurbo online program with a cognitive training game (PolyRules!) among youth ages 7-13 with overweight or obesity.
- Trial name
- NCT04747548
- Testing
- Kurbo Only, Kurbo + PolyRules!
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Obesity, Overweight
Avoid and Resist Strategies for Weight Management
The proposed randomized controlled trial tests two self-regulatory approaches to improve intentional weight loss and diet quality in individuals with overweight or obesity: (1) an environmental control strategy (AVOID) and (2) an…
- Trial name
- NCT05143931
- Testing
- Home food environment and grocery delivery (AVOID), Inhibitory control training (RESIST), WW
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids (TIGER Kids) Fitness Ancillary
The purpose of this ancillary study is to examine cardiorespiratory fitness, cognitive factors related to appetite, and objectively-measured food intake in a subsample of children and adolescents with overweight to severe obesity…
- Trial name
- NCT03611296
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Exercise, ADHD
Exercise Enhances Brain Function in Attention-deficit/Hyperactivity Disorder (ADHD)
The aim of the study was to investigate the different effects of exercise types on inhibitory control in children with attention-deficit/ hyperactivity disorder.
- Conditions
- Exercise, ADHD, Executive Dysfunction
- Trial name
- NCT05016102
- Testing
- Exercise type
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy
Nerve Stimulation to Modify a Spinal Reflex
This study will determine whether stimulating the nerves or the brain can modify the spinal reflex that controls the muscles that flex and extend the ankle.
- Trial name
- NCT00039819
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Preschoolers
Fundamental Movement Skills Training Improves Executive Functions in Preschoolers
This randomized controlled trial investigated the effects of a 12-week structured fundamental movement skills (FMS) training program on executive functions in 34 healthy preschoolers aged 5-6 years.
- Trial name
- FMS-EF-RCT (NCT07725354)
- Testing
- Fundamental Movement Skills Training, Regular Physical Activity
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Xi'an Physical Education University
School Readiness, Executive Function (Cognition)
Playful Physical Activity for Executive Functions and School Readiness in Preschool Children
Executive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children.
- Conditions
- School Readiness, Executive Function (Cognition), Preschool Child Development
- Trial name
- PPA-EF-SR (NCT07678294)
- Testing
- Playful Physical Activities Intervention, Regular Physical Education Curriculum
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dystonic Disorders, Healthy
Surround Inhibition in Patients With Dystonia
This study will use transcranial magnetic stimulation (TMS) to examine how the brain controls muscle movement in dystonia. Dystonia is a movement disorder in which involuntary muscle contractions cause uncontrolled twisting and…
- Trial name
- NCT00029601
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Osgood-Schlatter Disease
Rate of Torque Development in Adolescents With Osgood-Schlatter
Osgood-Schlatter is a growth-related condition involving multiple different types of tissue in the tendon-bone interface at the tibial tubercle.
- Trial name
- NCT05789095
- Testing
- Rate of torque development testing of knee flexors and knee extensors using a fixated handheld dynamometer (MicroFet 2, Hoggan, Scientific L.L.C., Salt Lake City, USA), sampling rate of 100hz)
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Stuttering, Childhood
Effects of Emotional Processes on Speech Motor Control in Early Childhood Stuttering.
This study will compare speech variability between preschool-age children who stutter and typically fluent, age-matched peers. Differences in emotional reactivity, regulation and speech motor control have been implicated in…
- Trial name
- NCT05003583
- Testing
- Speaking after viewing pictures with negative and neutral valence
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Institutionalization
Life Skills-Based Intervention on Substance Use Intention in Adolescents in Social Care Institutions
Objective: evaluate the impact of a Life Skills Training (LST) intervention on substance use intention by analyzing changes in neuropsychological organization and psychological regulation processes in adolescents living in social…
- Trial name
- CASA-HpV (NCT07492069)
- Testing
- Life Skills Training (LST), Psicoeducation Traditional
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Healthy Children, Preterm Birth
Executive Training and Brain in Children
The purpose of this study is to determine whether a daily executive training to cognitive inhibition, working memory or mindfulness as compared to an active control condition has a near- and far-transfer impact on brain and…
- Trial name
- APEX (NCT02989116)
- Testing
- Inhibition training, Working memory training, Mindfulness training
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Executive Function
Comparison Between Plyometrics and Calisthenics on Executive Function in School Going Children
The goal of this clinical trial is to compare the effects of calisthenics and plyometric exercises on executive functions in school-going children.
- Trial name
- NCT06770192
- Testing
- Calisthenics, Plyometric, Control
- Where
- Pakistan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Contraceptive Usage, Diffuse Noxious Inhibitory Control
Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women
The purpose of this study is tu assess the influence of oral contraceptives (OC) on diffuse noxious inhibitory control (DNIC) in healthy women, tested during high, low endogenous estrogens sessions and ovulatory period.
- Trial name
- NCT04365426
- Testing
- Mechanical stimulus, Thermal (cold) stimulus, Oral contraceptive (OC)
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Vina del Mar
Child Development, Executive Functions (EF)
Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development
Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers.
- Conditions
- Child Development, Executive Functions (EF), Emotion Regulation
- Trial name
- STTT (NCT07666802)
- Testing
- Emotion-Focused Shared Picturebook Reading, Standard Dialogic Picturebook Reading
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Motor Skills, Inhibitory Control
Effects of Coordinative Exercise on Physical Fitness, Motor Competence, and Inhibitory Control in Preschoolers
The goal of this study was to determine whether a structured coordinative exercise program could improve physical fitness, motor competence, and inhibitory control in preschool children.
- Conditions
- Motor Skills, Inhibitory Control, Physical Fitness
- Trial name
- NCT06631248
- Testing
- Coordinative exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University