Clinical trials: Inhibitory Control
CRPS, Chronic Regional Pain Syndrome
TNF-alpha Inhibition in CRPS: A Randomized Controlled Trial
Studying the effects of Etanercept (an anti-Tumor Necrosis Factor alpha) on early Chronic Regional Pain Syndrome (CRPS). Our hypothesis is that Etanercept will improve patient symptoms if given in early CRPS.
- Trial name
- NCT02031211
- Testing
- Etanercept
- Where
- United States
- Sponsor
- Stanford University
Obesity
Promoting Child Inhibitory Control Skills Around Food
Today's environment provides many hedonic stimuli that promote consumption of unhealthy energy-dense snack foods. It is widely recognized that a systems approach is required to deal with this complex problem.
- Trial name
- CHIC Play (NCT02077387)
- Testing
- CHild Inhibitory Control (CHIC) Play, Attention control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Trichotillomania
Online Response Inhibition Training for Trichotillomania
Trichotillomania (TTM) remains one of the most poorly-understood and inadequately-treated conditions. Research has shown poor response inhibition (RI; the ability to inhibit inappropriate but potent response) as an important…
- Trial name
- OTTM (NCT01984333)
- Testing
- Online cognitive training
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Wisconsin, Milwaukee
Teenage Pregnancy
Executive Functions and Emotional Intelligence in Pregnant Adolescents
Teenage pregnancy is a major global public health issue and is associated with a range of psychosocial, emotional, and developmental challenges.
- Trial name
- EFAEIPA (NCT07492082)
- Testing
- Psychological intervention program in executive functions and emotional intelligence
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Institutionalization
Life Skills-Based Intervention on Substance Use Intention in Adolescents in Social Care Institutions
Objective: evaluate the impact of a Life Skills Training (LST) intervention on substance use intention by analyzing changes in neuropsychological organization and psychological regulation processes in adolescents living in social…
- Trial name
- CASA-HpV (NCT07492069)
- Testing
- Life Skills Training (LST), Psicoeducation Traditional
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Anxiety Mild to Moderate, Inhibition (Psychology)
Tiny Heroes Compared to Treatment as Usual to Decrease and Prevent Anxiety Problems in Young Children - a Randomized Controlled Study
The aim of this randomized controlled trial is to evaluate the effectiveness and cost-effectiveness of Tiny Heroes, a parent-directed internet-delivered cognitive behavioral therapy (iCBT) program for anxiety problems in children…
- Trial name
- NCT07870213
- Testing
- Parent-directed online cognitive behavioral therapy, Treatment as Usual (TAU)
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Heterozygous Familial Hypercholesterolemia
Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders
A study to assess safety and efficacy of evolocumab (AMG-145) in paediatric subjects aged 10-17 years diagnosed with heterozygous familial hypercholesterolemia.
- Trial name
- HAUSER-RCT (NCT02392559)
- Testing
- Evolocumab
- Where
- 66 sites in United States, Australia and 24 more
- Volunteers
- 158 people
- Sponsor
- Amgen
Attention Deficit Hyperactivity Disorder
Inhibition Control of Children and Adolescents With ADHD
The objectives of this study are to investigate: 1. the effect of methylphenidate on attention; 2. the relations between methylphenidate and inhibition control and working memory; 3.
- Trial name
- NCT01677819
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Obsessive Compulsive Disorder (OCD)
NAC for Treatment-Resistant OCD and Other Related Disorders
This is a randomized, double-blind, placebo-controlled study investigating N-acetylcysteine (NAC) as an augmentation therapy for individuals with treatment-resistant obsessive-compulsive disorder (TR-OCD), studied within a…
- Trial name
- NCT06956157
- Testing
- N-Acetylcysteine Tablets
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Perennial Allergic Rhinitis
Study of the Effects of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol on Hypothalamic-Pituitary-Adrenal (HPA) Axis
To demonstrate the effects of ciclesonide applied as a nasal aerosol and ciclesonide aqueous (AQ) nasal spray on hypothalamic-pituitary-adrenal axis.
- Trial name
- NCT01033825
- Testing
- Ciclesonide HFA Nasal Aerosol 320 mcg, Ciclesonide HFA Nasal Aerosol 160 mcg, Ciclesonide Aqueous Nasal Spray 200 mcg
- Where
- 6 sites in United States
- Volunteers
- 310 people
- Sponsor
- Sumitomo Pharma America, Inc.
Attention Deficit Hyperactivity Disorder
Behavior in Children With Attention Deficit Hyperactivity Disorder and in Healthy Volunteers
The purpose of this study is to determine how the brain controls motor activity in children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT00026546
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- National Institute of Mental Health (NIMH)
Arrhythmia
The Effect of Proton Pump Inhibition on Palpitations
Feeling of palpitations with no clear arrhythmia is frequently encountered in clinical practice. The majority of these patients have documented sinus rhythm even while having symptoms.
- Trial name
- NCT03273634
- Testing
- Lansoprazole Pill
- Where
- Jordan
- Volunteers
- 150 people
- Sponsor
- Jordan Collaborating Cardiology Group
Primary Ciliary Dyskinesia
Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia
To evaluate the safety and efficacy of treatment with VX-371 with and without ivacaftor, and the effect of VX-371 with and without ivacaftor on quality of life (QOL) in subjects with primary ciliary dyskinesia (PCD).
- Trial name
- CLEAN-PCD (NCT02871778)
- Testing
- VX-371, Hypertonic Saline, VX-371 + HS
- Where
- 34 sites in United States, Canada and 6 more
- Volunteers
- 123 people
- Sponsor
- Parion Sciences
Attention Deficit Hyperactivity Disorder (ADHD), Attention Deficit Disorder (ADD)
Home-Based tDCS in Children With ADHD: A Randomized, Sham-Controlled tDCS and fNIRS Study
The purpose of this study is to investigate the efficacy of twenty daily sessions of home-based tDCS over the left DLPFC, right IFG on attention and response inhibition in children with ADHD.
- Trial name
- NCT04634006
- Testing
- Home-based transcranial direct current (tDCS) device
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- Onze Lieve Vrouw Hospital
Covid19
STOP-COVID19: Superiority Trial Of Protease Inhibition in COVID-19
COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There is currently no vaccine to prevent infection with SARS-CoV-2 and no therapeutic agent to treat…
- Trial name
- STOP-COVID19 (NCT04817332)
- Testing
- Brensocatib
- Where
- 16 sites in United Kingdom
- Volunteers
- 406 people
- Sponsor
- University of Dundee
Obsessive Compulsive Disorder (OCD)
The Effects and Neural Mechanisms of Vitamin D and Iron-Immune Homeostasis on Inhibitory Control in Obsessive-Compulsive Disorder
This study is a randomized, open-labled, no-treatment-controlled clinical trial designed to investigate the effects of vitamin D and iron-immune homeostasis on inhibitory control and the underlying neural mechanisms in patients…
- Trial name
- NCT07763977
- Testing
- Calcitriol and Iron Supplements
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial People's Hospital
Asthma
Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS
Asthma is a chronic inflammatory disorder of the airways with a variety of inflammatory processes contributing to the pathogenesis.
- Trial name
- NCT00486343
- Testing
- Zileuton CR
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Critical Therapeutics
Chronic Plaque Psoriasis
Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis
This is a double-blind, parallel group, vehicle-controlled study to assess the safety and efficacy of roflumilast (ARQ-151) 0.3% cream vs vehicle (placebo) cream for treatment of chronic plaque psoriasis (CPP) in adult…
- Trial name
- DERMIS-1 (NCT04211363)
- Testing
- Roflumilast 0.3% cream, Vehicle Cream
- Where
- 40 sites in United States, Canada
- Volunteers
- 439 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Exercise, ADHD
Exercise Enhances Brain Function in Attention-deficit/Hyperactivity Disorder (ADHD)
The aim of the study was to investigate the different effects of exercise types on inhibitory control in children with attention-deficit/ hyperactivity disorder.
- Conditions
- Exercise, ADHD, Executive Dysfunction
- Trial name
- NCT05016102
- Testing
- Exercise type
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Children, Chronic Renal Failure
Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients
In children with chronic kidney disease, progression to end-stage renal failure is associated with high patient morbidity and poor quality of life.
- Conditions
- Children, Chronic Renal Failure, Hypertension, Acquired Kidney Disease
- Trial name
- ESCAPE (NCT00221845)
- Testing
- ACE Inhibition, Intensified Blood Pressure Control, Add-on Angiotensin Receptor Blockade
- Where
- 33 sites in Czechia, France and 10 more
- Volunteers
- 400 people
- Sponsor
- Heidelberg University