Clinical trials: Injection Pain
Myofascial Pain Syndromes
Effect of Lidocaine and Ozone in Injection for Myofascial Pain
Myofascial pain syndrome (MPS) is a chronic soft tissue rheumatism characterized by tense, painful muscle bands, known as trigger points, located within the muscle or fascia.
- Trial name
- NCT06768281
- Testing
- Headache Impact Test-6 (HIT-6), Pittsburgh Sleep Quality Index (PSQI), Visual Analogue Score (VAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yağmur Malkoc
Pain, Breakthrough
Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain
Randomized control trial that to comparison the efficacy of injectable fentanyl in sublingual route versus oral morphine syrup for breakthrough pain in gynecologic cancer patients with chronic cancer pain Primary outcome : to…
- Trial name
- NCT05037539
- Testing
- Fentanyl Citrate 50Mcg/Ml Inj_#1, Morphine
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Computer-controlled Local Anesthesia
Effectiveness of Computerized Local Anesthesia in Reducing Local Anesthesia in Reducing Child Pain During Injection
Pain and anxiety management during injection of local anesthesia are major challenges in pediatric dentistry. The injection of local anesthesia is often perceived by children as the most painful step , The introduction of…
- Trial name
- RCT (NCT07688018)
- Testing
- star pen, Conventional 4% articaine delivery by carpule syringe
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Anesthesia, Local, Child Behavior
The Effect of Needle-free Injection System on Dental Injection Pain in Children
The aim of this study was to compare paediatric patients' pain perception and behavioural response during dental injection using needle free injection (NF) or traditional injection method (TM) over two consecutive visits.
- Conditions
- Anesthesia, Local, Child Behavior, Pain
- Trial name
- NCT06541925
- Testing
- Injection with the needle-free (NF) system, Injection with the traditional method (TM)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Erosive Oral Lichen Planus
Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus
After signing the informed consent, the participant will be allocated to either intervention or control group, then each participant in the intervention group will receive intralesional injections of platelet rich plasma…
- Trial name
- NCT03293368
- Testing
- Platelet rich plasma, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Healthy
Buzzy® Application in Pain
The research was conducted as a randomized controlled experiment to investigate the effect of Buzzy® on pain level during the measles-rubella-mumps (MMR) vaccine injection in 12-month-old infants.
- Trial name
- NCT04990648
- Testing
- Buzzy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Okan University
Pain
The Effect of Sucrose on Pain Relief During Venous Blood Sampling in Preterm Infants
Despite the fact that oral sucrose is the most frequently studied non-pharmacological intervention for procedural pain relief in infants, there is a paucity of data on the minimal effective dose.
- Trial name
- NCT02344368
- Testing
- 0.2 ml sucrose 25%, 0.5 ml sucrose 25%
- Where
- 2 sites in Norway, South Africa
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
Anxiety, Dental
Comparative Evaluation Between the Effectiveness of Vibration Assisted Syringe and Conventional Syringe
The study will be conducted to evaluate the effect of the vibration assisted syringe on pain perception and anxiety in children during intra oral injection of local anesthesia in comparison with conventional syringe.
- Trial name
- NCT04215055
- Testing
- vibraject
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anterior Cruciate Ligament Reconstruction
Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery
Patients scheduled to undergo knee arthroscopy with anterior cruciate ligament repair with graft from the ipsilateral hamstrings and gracilis will be randomized to one of three groups.
- Trial name
- NCT01868282
- Testing
- Hamstrings block, Obturator block, Control group
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Injection Pain Prevention, Injection Pain
The Effect of Simultaneous Versus Sequential Intramuscular Vaccine Injections on Pain Levels in Infants
This study was designed as a randomized controlled trial comparing simultaneous and sequential administration of intramuscular vaccines in infants.
- Trial name
- NCT07455305
- Testing
- Simultaneous injection, Sequential injection
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Child Behavior, Acute Pain
Improving Children's Cooperation During Dental Injection
This clinical trial aims to investigate how to increase children cooperation in dental settings using ideas adopted from psychology to make an effective interdisciplinary approach.
- Trial name
- NCT03978390
- Testing
- behavioral priming, endowment effect, Positive reinforcement
- Sponsor
- University of Alberta
TMJ Disc Disorder, TMJ Pain
I-PRF After Arthrocentesis Plus Botox Injection to Lateral Pterygoid Muscle in Treatment of Anterior Disc Displacement
Aim of Study : To evaluate the efficacy of TMJ arhtrocentesis followed by injection of liquid platelet rich fibrin (I-PRF ) in addition to intramuscular injection of lateral pterygoid muscle with botulinum toxin on clinical…
- Trial name
- NCT06207955
- Testing
- TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin And Botulinum Toxin Type A, TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Fayoum University
Pain, Ecchymosis
Effect of Hypericum Perforatum Oil on Ecchymosis and Pain
Low molecular weight heparin is a drug with anticoagulant and antithrombotic effects. This drug is frequently administered subcutaneously to patients by nurses.
- Trial name
- NCT06367036
- Testing
- Topical hypericum perforatum oil intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Uskudar University
Pain
Comparison of Two Different Methods of Delivering Local Analgesia During Intra-articular Corticosteroid Injections in Children With Juvenile Idiopathic Arthritis
Chronic arthritis (inflammation of joints) in children is known as Juvenile Idiopathic Arthritis (JIA). Often, to control the swelling and to help reduce the pain in the joint, medications (steroids) are injected into the joint.
- Trial name
- NCT00465504
- Testing
- iontophoresis
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pain, Acute, Fear
ShotBloker and Helfer Skin Tap Technique During Intramuscular Injection in Children
To examine the effect of the Helfer skin tap technique and ShotBloker application on pain and fear experienced during intramuscular injection in children aged 6-12 in the pediatric emergency unit.
- Conditions
- Pain, Acute, Fear, Emergencies, Child, Only
- Trial name
- NCT05563233
- Testing
- Helfer skin tap technique, Shot Blocker
- Where
- Turkey (Türkiye)
- Volunteers
- 177 people
- Sponsor
- Tarsus University
Intramuscular Injection
The Effect of Two Different Methods Applied During Intramuscular Injection on the Level of Pain and Fear in Children
This study was planned to determine the effects of using virtual reality glasses and manual pressure during intramuscular injection on the level of pain and fear in children.
- Trial name
- NCT05833854
- Testing
- Virtual reality glasses group, Manual pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Selmin Kose
Psoriasis, Pain
Reduction of Pain Caused by Biologic Drugs in Psoriasis
Injectable biologic drugs are used as a treatment of psoriasis. These injections can sometimes be associated with pain. In this study the investigators aim to reduce the pain by applying heat or ice to the skin 2-3 minutes before…
- Trial name
- NCT02168244
- Testing
- Heating Pack, Ice pack
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Icahn School of Medicine at Mount Sinai