Clinical trials: Innate Inflammatory Response
Prematurity, Neonatal Sepsis
Defects in Opsonophagocytosis in Premature Infants
The purpose of the study is to characterize innate immune function of premature infants, and identify defects that may be responsible for the development of bacterial sepsis.
- Trial name
- NCT00866567
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Crohn Disease
The Innate Immune Response and Enteric Nervous System in Crohn's Disease.
The study aims to explore the relationships between inflammation, nerve changes, and the expression of interferon-stimulated proteins in inflamed and non-inflamed bowel areas from patients with Crohn's disease.
- Trial name
- NCT06485193
- Testing
- Immunohistochemistry
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aalborg University Hospital
Sepsis, Pneumonia
Genetic Variation and Immune Responses After Injury
Our overall hypothesis is that genetic variations in innate immunity genes predispose patients to varying responses after injury by altering the systemic and local inflammatory responses.
- Conditions
- Sepsis, Pneumonia, Trauma, Burn
- Trial name
- NCT00294697
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Preterm Infants, Term Infants
The Intestinal Innate Immune System in Newborns. Development and Inflammation in Health and Disease
The goal of this observational study is to determine the normal development of the human intestinal immune system in premature and mature neonatal life and to determine the pathophysiology behind life-threatening gastrointestinal…
- Conditions
- Preterm Infants, Term Infants, Necrotising Enterocolitis, Atresia; Bowel
- Trial name
- INTINE (NCT06092463)
- Where
- 2 sites in Denmark
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet