Clinical trials: Interaction
Autism Spectrum Disorder, Parent-Training
Clinical Efficacy of Cooperative Parent-Mediated Therapy (C-PMT_in_ASD)
The research highlights the lack of studies assessing the effectiveness of evidence-based interventions for ASD in community services.
- Trial name
- C-PMT in ASD (NCT06692946)
- Testing
- Cooperative Parent-Mediated therapy, Treatement as Usual
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- ALESSANDRA CARTA
Healthy
Effects of Kava on the Body's Elimination of Caffeine and Dextromethorphan
This study will examine how kava-a widely used herbal remedy-may affect the body's elimination of other medicines. Many people take kava to reduce anxiety or cause sedation.
- Trial name
- NCT00009542
- Testing
- kava (Piper methysticum)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Asthma
EmPhAsIS: Empowering Pharmacists in Asthma Management Through Interactive SMS
Between 8% and 12% of Canadians suffer from asthma. Although there are effective and inexpensive treatments, adherence to asthma treatment is amongst the lowest for all chronic diseases.The purpose of this study is to determine…
- Trial name
- NCT02170883
- Testing
- Interactive SMS, Usual care
- Where
- Canada
- Volunteers
- 271 people
- Sponsor
- University of British Columbia
Pediatric Disorder, Genetic Predisposition
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this…
- Conditions
- Pediatric Disorder, Genetic Predisposition, Dystonia, Secondary, Dystonia
- Trial name
- TRIKE2 (NCT06554288)
- Testing
- Trihexyphenidyl
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Adolescent Behavior
Step Up for STEM and Health Careers
The goal of this randomized controlled trial is to evaluate "Step Up for STEM and Health Careers". The "Step Up for STEM and Health Careers" ("Step Up") game is an interactive, digital resource that includes the key elements of a…
- Trial name
- NCT06445751
- Testing
- Step Up for STEM and Health Careers ("Step Up") game, Educational PowerPoint Presentation on Diversity in STEM Careers
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Autism Spectrum Disorders
Social Interactions: Ocular Explorations and Pupillometry in Autism
The primary objective of this work will first to characterize in typical childhood, visual exploratory behavior and pupillary response associated with salience of human social stimuli (faces and body movements), and then to…
- Trial name
- ISEOP (NCT01647295)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism, Autism Spectrum Disorder
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related…
- Conditions
- Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
- Trial name
- NCT03553875
- Testing
- Memantine Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Behavior Problem, Parenting
Evaluation of Intensive Parent-Child Interaction Therapy"
The purpose to the current study was to examine the comparative efficacy of a more condensed intensive version of Parent-Child Interaction Therapy (I-PCIT; 5 days/week over the course of 2 weeks) versus a more traditional weekly…
- Trial name
- IPCIT (NCT04077112)
- Testing
- Parent Child Interaction Therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida International University
Hirschsprung Disease
Hirschsprung's Advances; Working Towards Autologous tIssue therapIes
Children with Hirschsprung's Disease (HSCR) have no normal nerve cells in the lower end of their bowel. This can cause babies to die if left untreated treated.
- Trial name
- HAWAII (NCT06590142)
- Testing
- Observational study of tissue specimens
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Cerebral Palsy
Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Children With Cerebral Palsy
Cerebral Palsy (CP) is a major cause of impairments in child population. This disease justifies an intensive and prolonged multidisciplinary rehabilitation which can be optimised by robotics.
- Trial name
- NCT01700153
- Testing
- Robotic-assisted therapy, Classical therapy
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Human Papillomavirus
Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents
Emerging communication technologies, such as text messaging offer low-cost, scalable opportunities to improve health literacy and promote healthy behaviors, such as vaccination.
- Trial name
- NCT02236273
- Testing
- Conventional text message reminder, Enhanced text message reminders
- Where
- United States
- Volunteers
- 956 people
- Sponsor
- Columbia University
Risky Sexual Behavior, Emotion Regulation
An Interactive Education Program to Reduce High Risk Behavior in Adolescents Ph II (iTRAC HERO)
Using the efficacious iTRAC intervention to enhance emotion regulation competencies as a foundation, this study will create and test iTRAC-HERO to teach emotion regulation skills in the context of sexual health education.
- Conditions
- Risky Sexual Behavior, Emotion Regulation, Adolescent Behavior
- Trial name
- iTRAC-HERO (NCT06894277)
- Testing
- iTRAC-HERO
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Klein Buendel, Inc.
Physical Disability
Use of Adapted Controllers for Active Video Gaming in People With Physical Disabilities
The purpose of this study is to compare the effectiveness of off-the-shelf (OTS) and adapted game controllers on quality of game play, enjoyment, and energy expenditure during active video gaming in persons with mobility…
- Trial name
- NCT02994199
- Testing
- Active video gaming
- Volunteers
- 105 people
- Sponsor
- University of Alabama at Birmingham
Dysbiosis
Interactions Between Skincare Product Ingredients and the Skin Microbiome
This is a study of the influence of skincare products containing chemicals such as parabens and phthalates on the skin microbiome.
- Trial name
- NCT04476732
- Testing
- Paraben-free skincare product, Paraben-containing skincare product
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Chronic Disease
Communication Model to Self-Care - Regardless of Health Literacy
Healthcare systems all over the world are developing in a way that compels patients to become more active in the management of their own health and disease - a development that changes the role of modern patients and the skills…
- Trial name
- NCT04929314
- Testing
- Systematic Interactive Communication Model to Strengthen Self-Care Regardless of Health Literacy Level
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- University College of Northern Denmark
Development, Infant, Perinatal Disorder
Early Childhood : Action Research in the Lunévillois Area (PERL)
The PERL project is a research in prevention in perinatality. The objective of this research is to offer preventive and regular care at familie's home in the Lunévillois area, while integrating it into the existing practices of…
- Trial name
- PERL (NCT03506971)
- Testing
- Psychologist's evaluation, Pediatric Nurse's interventions, Joint home visits
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Palliative Care
Contextualizing Care for Patients With a Serious Illness
When people become seriously ill, healthcare decisions are influenced not only by their medical condition, but also by their personal situation, values, wishes, and daily life circumstances.
- Trial name
- SVPII-TRAIN (NCT07764263)
- Testing
- Contextualized Care Communication Training
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Breast Neoplasms, Metastases, Neoplasm
Safety, Efficacy and Pharmacokinetic Between Capecitabine and Exisulind in Metastatic Breast Cancer Patients
The primary objective of the phase I study is to determine a safe dose for combination therapy with capecitabine and exisulind. A secondary objective is to assess pharmacokinetic interactions between the two drugs and assess the…
- Trial name
- NCT00037609
- Testing
- Capecitabine, Exisulind
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Pain
Drug Interactions Between Paracetamol and Setrons in Pain Management
The aim of this study is to demonstrate that the association paracetamol / ondansetron is not as effective as the association paracetamol / droperidol in the treatment of pain in children following tonsillectomy.
- Trial name
- PARATRON (NCT01432977)
- Testing
- paracetamol /droperidol, paracetamol / ondansetron
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Limoges