Clinical trials: Internal Hernia
Pain, Postoperative, Hernia, Inguinal
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
The purpose of this study is to test whether pregabalin added to the standard of care with dosing starting preoperatively and continuing for 1 week post surgery will decrease the intensity of acute post-operative pain following…
- Trial name
- NCT00551135
- Testing
- Pregabalin
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 425 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Inguinal Hernia
Erector Spinae Versus Ilioinguinal/ Ilio-hypogastric Block in Children Undergoing Inguinal Surgeries
Investigators aim to compare the efficacy of US-guided II/IH nerve block versus US-guided ES block for pediatric unilateral inguinal hernia repair with respect to postoperative analgesia
- Trial name
- NCT03640598
- Testing
- Ilioinguinal/iliohypogastric nerve blocks, Erector spinae nerve block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Inguinal Hernia
Effects of Esketamine at Subanesthetic Dose on Emergence Delirium in Preschool Children Undergoing Ambulatory Laparoscopic Surgery
Emergence delirium (ED) is a manifestation of acute postoperative brain dysfunction that occurs with a relatively high frequency after pediatric anesthesia.
- Trial name
- NCT06789185
- Testing
- 0.1mg/kg esketamine, 0.2mg/kg esketamine, 0.1ml/kg normal saline
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Qiu jinpeng
Hernia, Diaphragmatic, Hypertension, Pulmonary
Chronic Sildenafil for Severe Diaphragmatic Hernia
The purpose of this study is to test if sildenafil is effective in the treatment of infants with severe congenital diaphragmatic hernia (determined by the presence of prolonged pulmonary hypertension or prolonged oxygen…
- Conditions
- Hernia, Diaphragmatic, Hypertension, Pulmonary, Hypoplasia, Pulmonary
- Trial name
- NCT00133679
- Testing
- sildenafil
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Inguinal Hernia
Hernia Exploration oR Not In Infants Analysis
This study evaluates the effectiveness and cost-effectiveness of contralateral surgical exploration during unilateral inguinal hernia repair in children younger than six months with a unilateral inguinal hernia.
- Trial name
- HERNIIA (NCT03623893)
- Testing
- Contralateral exploration
- Where
- 7 sites in Netherlands
- Volunteers
- 416 people
- Sponsor
- Amsterdam UMC, location VUmc
Congenital Diaphragmatic Hernia
Delayed Cord Clamping for Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality and need for life-saving interventions such as extracorporeal membrane oxygenation (ECMO), nitric oxide, and vasopressor…
- Trial name
- DING (NCT03314233)
- Testing
- DING
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Inguinal Hernia
Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years
Laparoscopic techniques have been applied widely to the management of various common pediatric surgical diseases. Current evidence lacks sufficient quality to justify the widespread adoption of the laparoscopic approach to the…
- Trial name
- NCT00716768
- Testing
- Laparoscopic Inguinal Hernia Repair, Open Inguinal Hernia Repair
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Congenital Hernia
Laparoscopic Recurrent Inguinal Hernia Repair
Laparoscopic management of recurrent inguinal hernia in children has been recently introduced in surgical practice. One of the most important advantages of using the laparoscopic approach in cases with recurrent inguinal hernia…
- Trial name
- NCT04266561
- Testing
- hernia repair
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Al-Azhar University
Ventral Hernia
Longitudinal Relaxing Incision as a Technique for Recurrence Prevention in Ventral Hernia
The aim of the study is showing the efficiency of using Longitudinal relaxing incision as a Technique for recurrence prevention in Ventral Hernia
- Trial name
- NCT05526209
- Testing
- using longitudinal relaxing incision as a technique for recurrence prevention in ventral hernia
- Volunteers
- 40 people
- Sponsor
- Assiut University
Virtual Reality, Congenital Diaphragmatic Hernia
Virtual Reality and Congenital Diaphragmatic Hernia
The study has been designed to investigate the effect of 12 weeks of using virtual reality based exercises on pulmonary functions, exercise capacity, functional performance, and quality of life in children with…
- Conditions
- Virtual Reality, Congenital Diaphragmatic Hernia, Children
- Trial name
- NCT05612503
- Testing
- Traditional physical therapy program, Virtual reality-based exercises
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Qassim University
Enterocolitis, Necrotizing, Atresia; Bowel
Timing of Stoma Closure in Neonates
Some babies require emergency surgery on their tummy in the first few months of life. This is most commonly because they were born prematurely and developed a bowel problem (called NEC) or a blockage of the bowel.
- Conditions
- Enterocolitis, Necrotizing, Atresia; Bowel, Gastroschisis, Meconium Ileus
- Trial name
- ToSCiN (NCT04713579)
- Testing
- No intervention - observational study
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Manchester University NHS Foundation Trust
Hernia, Inguinal, Hernia, Femoral
Chronic Pain After Groin Hernia Repair
In the present study the investigators aimed to investigate the relationship between surgical methods and chronic pain in over 20 000 patients who underwent groin hernia repair in Sweden
- Trial name
- NCT02751190
- Testing
- Totally ExtraPeritoneal (TEP) repair, TransAbdominal PrePeritoneal (TAPP) repair, Open anterior mesh repair
- Volunteers
- 24,607 people
- Sponsor
- Umeå University
Congenital Diaphragmatic Hernia
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science
The goal of this study is to identify genes that convey susceptibility to congenital diaphragmatic hernia in humans. The identification of such genes, and examination of their structure and function, will enable a delineation of…
- Trial name
- DHREAMS (NCT00950118)
- Where
- 14 sites in United States, Egypt
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hernia, Inguinal
3D vs 2D HD Laparoscopy in Inguinal Hernia Repair
Inguinal hernia can be repaired laparoscopically. In the normal laparoscopy there are only two-dimensional view, which is somewhat challenging when operating in three-dimensional environment.
- Trial name
- NCT02367573
- Testing
- 2D laparoscopic TAPP inguinal hernia repair, 3D laparoscopic TAPP inguinal hernia repair
- Where
- Finland
- Volunteers
- 278 people
- Sponsor
- Helsinki University Central Hospital
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Incisional Hernia
Giant Ventral Incisional Hernia: Abdominal Wall Function, Respiratory Performance and Quality of Life
One of five patients undergoing open abdominal surgery develops an abdominal wall defect (incisional hernia) as a late complication. A fraction of these are "giant" hernia with a fascial defect beyond 10 cm.
- Trial name
- GIVINA (NCT02011048)
- Testing
- Endoscopic components separation
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Bispebjerg Hospital
Gastroschisis
Sutureless vs Sutured Gastroschisis Closure
This study aims to prospectively assess outcomes of sutureless versus sutured gastroschisis closure with a randomized control trial. The parameters of this trial were determined using our retrospective study as pilot data.
- Trial name
- NCT01094587
- Testing
- Gastroschisis closure with suture, Gastroschisis closure without suture
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Stanford University
Indirect Inguinal Hernia, Undescended Testis
INVESTIGATION OF THE GENETIC ETIOLOGY OF HERNIA SAC DEVELOPMENT IN MALE CHILDREN WITH UNDESCENDED TESTIS AND INGUINAL HERNIA
The aim of the project is to elucidate the genetic etiology underlying the development of the processus vaginalis (PV) in male children with indirect inguinal hernia (IIH) and undescended testis (UT), through the investigation of…
- Trial name
- NCT07586332
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Trakya University
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Abdominal Wall Hernia
Clinical Study of Hernia Ring Closure Method in Laparoscopic Abdominal Wall Hernia Repair
By comparing the time of closing the hernia ring, the degree of pain, and the recovery of gastrointestinal tract in different groups Intervening, infection, recurrence and medical cost, to find out whether patients with abdominal…
- Trial name
- NCT05661097
- Testing
- Suture mode
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Bo Li