Clinical trials: Intervention Condition
Attention Deficit Hyperactivity Disorder
Brain-Computer Interface (BCI) Based Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
This study aims to examine the efficacy of a brain-computer interface system for the treatment of inattentive symptoms of Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01344044
- Testing
- BCI
- Where
- Singapore
- Volunteers
- 192 people
- Sponsor
- National Healthcare Group, Singapore
Spinal Muscular Atrophy
A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)
The primary objective of this study is to examine the clinical efficacy of nusinersen (ISIS 396443) administered intrathecally to participants with later-onset Spinal Muscular Atrophy (SMA).
- Trial name
- CHERISH (NCT02292537)
- Testing
- Nusinersen
- Where
- 24 sites in United States, Canada and 8 more
- Volunteers
- 126 people
- Sponsor
- Biogen
Pediatric Obesity
Childhood Obesity Intervention Study
Globally, childhood overweight and obesity is a public health problem. Although the rising trend in children's body mass index (BMI) has plateaued in some high-income countries, it has accelerated in low- and middle-income…
- Trial name
- NCT03665857
- Testing
- a multicomponent intervention
- Where
- China
- Volunteers
- 1,392 people
- Sponsor
- Peking University
Hearing Impaired Children
Inter Disciplinary Approach to Vocabulary Development in Hearing Impairment
The research aims to address to address the role of interdisciplinary working between professionals in the field of speech and language pathology/therapy.
- Trial name
- NCT04962828
- Testing
- Vocabulary based intervention- Non Collaborative, Vocabulary based intervention - Collaborative
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Anxiety
Interventional Study of Anxiety Symptoms in the Implantable Cardioverter Defibrillator (ICD) Patient
This study will compare the effectiveness that Cognitive Behavioral Therapy has on decreasing the amount of anxiety, as well as the number of inappropriate firings that a patient with an ICD may experience.
- Trial name
- NCT00851071
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The Cleveland Clinic
Lactate Blood Increase, Trauma Blunt
Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention
Serum lactate has been utilized as a standard in guiding management of orthopedic injuries. Elevated preoperative lactate has been associated with a higher likelihood of postoperative complications.
- Conditions
- Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
- Trial name
- NCT05611398
- Testing
- Orthopedic Surgery
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Arrowhead Regional Medical Center
Endodontic Disease
Outcome of Regenerative Endodontic Procedures
Clinical management of immature non-vital (necrotic) permanent teeth is challenging, due to inherent structural weakness. Earlier management of such teeth relied on the traditional calcium hydroxide (Ca(OH)2) apexification…
- Trial name
- NCT05612451
- Testing
- Regenerative Endodontic Procedures, non-setting calcium hydroxide, modified triple antibiotic paste
- Where
- Jordan
- Volunteers
- 45 people
- Sponsor
- King Abdullah University Hospital
Breast Cancer
A Study of HR+/HER2- Metastatic Breast Cancer Patients Treated With Palbociclib Together With an Aromatase Inhibitor From 2017 to 2023 in Denmark.
The purpose of this study is to describe the effect of the medicine palbociclib when given together with an aromatase inhibitor for treatment of breast cancer.
- Trial name
- NCT06307457
- Testing
- Palbociclib in combination with AI
- Where
- Denmark
- Volunteers
- 604 people
- Sponsor
- Pfizer
Externalizing Problems, Internalizing Problems
Psychological Intervention for Child Mental Health Based on Parental Reflective Functioning to Enhance Positive Parenting
In this study we aim to verify the effectiveness of a psychological intervention for preschool children, 3 to 6 years of age, with psychological problems or disorders, arising from adversity, Skills4Parenting+.
- Trial name
- SK4Parenting+ (NCT05490745)
- Testing
- Skills4Parenting+, Waiting-list (nocebo)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
Ataxia Telangiectasia in Children, Ataxia Telangiectasia
Home-based Complex Intervention for Children With Ataxia Telangiectasia
Ataxia telangiectasia is a rare, genetic and progressive condition with no known cure. Therapies present a mainstream management option and have the potential to offer optimisation of fitness and general health.
- Trial name
- NCT05692622
- Testing
- Whole-body exercise and respiratory exercise
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Plymouth
Fragile X Syndrome, Genetic Diseases
Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
The purpose of the study is to test the efficacy of a 20 week multi-modal treatment comprised of lovastatin or placebo, and the Parent-implemented Language Intervention (PILI) in children with fragile X syndrome (FXS).
- Trial name
- NCT02642653
- Testing
- Lovastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Autism Spectrum Disorders
Using Web-based Technology to Expand and Enhance Applied Behavioral Analysis Programs for Children With Autism in Military Families
The purpose of this study is to determine the extent to which technology may be used to provide (a) state-of-the-art assessment and intervention for children diagnosed with autism and (b) parent and tutor training for those who…
- Trial name
- NCT01614275
- Testing
- Technology-Enhanced Parent Training, Technology-Enhanced Tutor Training, Technology-enhanced Early Intensive Behavioral Intervention
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Nebraska
Nerve Block, Analgesia
ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure
This is a prospective randomized double-blind non-inferiority trial designed to test the hypothesis that erector spinae plane block (ESPB) is non-inferior to thoracic paravertebral block (TPVB) in postoperative pain control after…
- Conditions
- Nerve Block, Analgesia, Pectus Excavatum
- Trial name
- NCT05034601
- Testing
- ESPB group, TPVB group
- Where
- China
- Volunteers
- 68 people
- Sponsor
- West China Hospital
Stress Disorders, Post-Traumatic
Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU
This study is designed to examine three treatment conditions for traumatized youth: Cue-Centered Treatment (CCT), Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT), and Treatment as Usual (TAU) to determine which treatment…
- Trial name
- NCT02926677
- Testing
- Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- Stanford University
Respiratory Syncytial Viruses
A Two-Part Infant Study for Early Diagnosis of Respiratory Syncytial Virus (RSV) and Evaluation of JNJ-53718678 in RSV Acute Respiratory Tract Disease
The purpose of this two-part designed study is to assess in the setting of a planned early interception of pediatric RSV disease, early viral and disease kinetics (observational stage) and the antiviral effects of an Respiratory…
- Trial name
- NCT04068792
- Testing
- RSV Mobile Application, JNJ-53718678 2.5 mg/kg, JNJ-53718678 3 mg/kg
- Where
- 10 sites in Argentina, Belgium and 3 more
- Volunteers
- 22 people
- Sponsor
- Janssen Research & Development, LLC
Asthma
Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma
The investigators aim to pilot the role of school based intervention consisting of enhanced integrated pest management, classroom air purifiers and cleaning improves asthma morbidity.
- Trial name
- NCT01913795
- Testing
- integrated pest management, air purifier
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain
A Handheld Tool for Active Distraction of Children and Adolescents During Painful Procedures
The goal of this clinical trial is to learn if the handheld device Grasp, works to reduce pain and distress during small procedures involving a needle prick in children and adolescents.
- Trial name
- NCT06984939
- Testing
- Grasp
- Where
- Norway
- Volunteers
- 126 people
- Sponsor
- Haukeland University Hospital
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe and effective treatment for varicose veins.
- Trial name
- NCT02192411
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Midwest Vein Center
Pain, Acute, Emotional Distress
Veın Imagıng Devıce And Vırtual Realıty
The aim of this study was to evaluate the effect of a vein imaging device and virtual reality distraction on the success of peripheral intravenous catheter (PIC) placement, intervention duration, emotional appearance, pain, fear…
- Conditions
- Pain, Acute, Emotional Distress, Fear, Anxiety State
- Trial name
- ven-VR (NCT06243419)
- Testing
- vein viewer, virtual reality, vein viewer and virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Dokuz Eylul University
Nursing Caries
Foot Bath for Heel Warming Before Heel Lance
Foot bath is a simple warm application method that creates a feeling of comfort and positive effects on health have been reported in the literature. There are studies reporting the benefits of footbath for different groups.
- Trial name
- NCT05220930
- Testing
- Foot bath for heel warming, Ineffective heel warming with thermofor
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
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