Clinical trials: Intervention Effectiveness
Overweight, Obesity
Liquid Meal Replacements in Conjunction With Lifestyle Intervention in Overweight Adolescents
In this 3-month pilot study, we will introduce to 40 adolescents "at risk for overweight" (i.e., a BMI/age >85th percentile) a structured meal plan consisting of meal replacements, fruits, vegetables, whole grains, lean protein…
- Trial name
- NCT00207519
- Testing
- weekly behavioral modification group, liquid meal replacements
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Depression, Anxiety
Effectiveness of Enhanced Mental Health Support for Young People
The aim of the research project is to measure the effectiveness of an early and rapid psychiatric nurse intervention at schools in improving the emotional well-being and functioning of adolescents.
- Conditions
- Depression, Anxiety, Emotional Stress
- Trial name
- Nopsatuki (NCT05356949)
- Testing
- Intervention
- Where
- Finland
- Volunteers
- 124 people
- Sponsor
- Turku University Hospital
Children Sedation
Comparison of Chlorpromazine or Pentobarbital Premedications for Pediatric Imaging Procedures
Sedation is often required for pediatric medical imaging procedures to ensure compliance and quality images. Recommendations exist regarding pediatric sedation, but there are currently no guidelines regarding the choice of the…
- Trial name
- PREIMAPED (NCT04350528)
- Testing
- Chlorpromazine or Pentobarbital
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Brest
Fetal Alcohol Syndrome, Teen Pregnancy
Evaluating the Efficacy of a Video Based Intervention to Educate Teen Moms About Fetal Alcohol Syndrome (FAS)
Evaluating the efficacy of a video about FAS to determine whether it has an impact on knowledge about FAS and their likelihood to participate in risk taking behavior.
- Trial name
- NCT00747630
- Testing
- An educational video about Fetal Alcohol Syndrome
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Texas Tech University Health Sciences Center
Obesity, Exercise
Structured Exercise Prescription Program in Obese Children
This controlled clinical trial aims to compare the effects of a multicomponent program that includes structured personalized exercise prescription in children with obesity with a control group that will be enrolled in a…
- Conditions
- Obesity, Exercise, Cardiovascular Risk Factor, Liver Diseases
- Trial name
- NCT03552367
- Testing
- Personalized structured exercise program, Non personalized non-structured exercise program
- Where
- Mexico
- Volunteers
- 140 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Epilepsy With POS With or Without Secondary Generalization
Study to Look at How Effective Briviact is as add-on Treatment for Patients With Epilepsy With Partial Onset Seizures
Study is the first study after commercialization of brivaracetam. It is designed to collect real world information on the effectiveness of brivaracetam in patients with Partial Onset Seizure epislepsy who are treated in standard…
- Trial name
- BASE (NCT02687711)
- Where
- 44 sites in Denmark, Germany and 7 more
- Volunteers
- 544 people
- Sponsor
- UCB Biopharma S.P.R.L.
Developmental Dyslexia
Telerehabilitation vs. in Presence Rehabilitation of Reading Disorders Using the Rhythmic Reading Training (RRT)
The aim of the study is to compare the effectiveness of telerehabilitation vs. in presence rehabilitation of reading disorders, using a rhythm-based intervention for reading (i.e., Rhythmic Reading Training)
- Trial name
- NCT04995471
- Testing
- In presence RRT - prototype software, In presence RRT - online platform, Tele-RRT - prototype software
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Zinc Deficiency, Diarrhea
Water-based Zinc Intervention Trial in Zinc Deficient Children
The overall aim of this trial is to determine whether the use of the household-based water treatment device Life Straw Family (LSF) can be an effective strategy to improve zinc status and health status of vulnerable populations…
- Trial name
- NCT01472211
- Testing
- zinc enriching filter (LifeStrawFamily), disinfection tablets
- Where
- Benin
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Contraceptive Use After Emergency Contraception
Initiating Contraception After Emergency Contraception From Pharmacy
Pharmacists do not provide immediate contraception to women after emergency contraception (EC); they can only give advice on local contraceptive services.
- Trial name
- NCT01738971
- Testing
- rapid access, one month progestogen only pill
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- University of Edinburgh
Social Needs, Health-Related Social Needs
The Social Needs Assistance for Hospitalized Kids Trial
The goal of this clinical trial is to determine the best way to help families access social and economic support services in order to improve children's health for hospitalized children and their families/caregivers.
- Conditions
- Social Needs, Health-Related Social Needs, Social Determinants of Health (SDOH), Social Needs Status
- Trial name
- SNAK (NCT07687238)
- Testing
- Active Assistance by Navigators, Passive Referral
- Where
- 6 sites in United States
- Volunteers
- 1,880 people
- Sponsor
- University of California, San Francisco
Rhinitis, Allergic, Perennial and Seasonal
Regulatory AVAMYS Nasal Spray PMS
Non-interventional, open-label, single group, multicentric post-marketing surveillance to monitor the safety and effectiveness of AVAMYS nasal spray administered in Korean patients according to the prescribing information.
- Trial name
- NCT01001130
- Testing
- fluticasone furoate group
- Where
- South Korea
- Volunteers
- 3,244 people
- Sponsor
- GlaxoSmithKline
Diabetes
Adolescent Fitness Assessment Program
The purpose of this study is to implement a peer modeling intervention to improve self-efficacy and aerobic fitness in obese youth.
- Trial name
- AFAP (NCT01382121)
- Testing
- Peer Modeling, Control
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Premature Birth
Family-Centered Intervention for Preterm Children: Effects at School Age and Biosocial Mediators
This study is to extend our previous research to longitudinally examine the effectiveness of intervention programs (FCIP and UCP) for VLBW preterm children in Taiwan at seven years of age.
- Trial name
- NCT03668626
- Testing
- Family-centered intervention program (FCIP)
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Challenging Behaviour
Evaluation of Parent Intervention for Challenging Behaviour in Children With Intellectual Disabilities (EPICC-ID)
Children with intellectual disabilities are likely to present with challenging behaviour. Parent mediated interventions have shown utility in influencing child behaviour, although there is a paucity of UK research into…
- Trial name
- NCT03086876
- Testing
- Level 4 Stepping Stones Triple P (SSTP)
- Where
- 4 sites in United Kingdom
- Volunteers
- 261 people
- Sponsor
- University College, London
Physical Activity, Adiposity
Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
Coordinated project whose objectives are: a) to assess the effectiveness of a physical activity intervention (MOVI-KIDS) on preventing obesity and improving fitness during the adiposity rebound period; and b) to examine the…
- Conditions
- Physical Activity, Adiposity, Children, Obesity
- Trial name
- MOVI-KIDS (NCT01971840)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Preterm, Extreme Prematurity
Effectiveness of Home Based Early Intervention of Extremely Premature Infant by Parent
This study is to prove the effectiveness of home based early intervention of extremely premature infant by Parent.
- Conditions
- Preterm, Extreme Prematurity, Early Intervention, Developmental Delay
- Trial name
- NCT05334550
- Testing
- Home Based Early Intervention by Parent
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center
Sleep Problem, Behavior, Child
Parents Advancing Toddler Health
Although early interventions can improve health equity in young children living in poverty, this promise often is not realized because of barriers to family engagement.
- Trial name
- PATH (NCT04824989)
- Testing
- Sleep Health in Preschoolers (SHIP), Family Check-Up (FCU), Oral Health, Child Safety, and Environmental Health Intervention (Active Control)
- Where
- 2 sites in United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
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