Clinical trials: Interventional Study
Food Habits
Fostering Healthy and Sustainable Diets Through School Meals
School meals have considerable potential to shape children's diets and reduce the climate impact of meals. This study applies linear programming for developing and implementing a climate friendly, nutritious and affordable school…
- Trial name
- OPTIMAT (NCT04168632)
- Testing
- OPTIMAT
- Where
- Sweden
- Volunteers
- 1,635 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Retinopathy of Prematurity (ROP)
Intravitreal Ranibizumab for Aggressive Posterior Retinopathy of Prematurity: A Prospective Interventional Case Series
Aggressive posterior retinopathy of prematurity (AP-ROP) is a severe form of retinopathy of prematurity that can progress rapidly and lead to retinal detachment and permanent vision loss if not treated promptly.
- Trial name
- NCT07721298
- Testing
- Intravitreal Ranibizumab injection
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Ain Shams University
Suicidal Ideation
Circles of Hope: Group Intervention for Adolescents With Suicidal Symptoms
This pilot study examines the feasibility, acceptability, and preliminary outcomes of a short-term group psychotherapy intervention for adolescents experiencing suicidal symptoms without immediate suicidal intent.
- Trial name
- COH (NCT07818863)
- Testing
- Circles of Hope Group Psychotherapy
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Robotic Surgical Procedures
Outcomes of Pediatric Robotic Surgery at a Tertiary Children's Hospital
This is a single-center retrospective observational cohort study evaluating surgical and clinical outcomes in pediatric patients undergoing robotic surgery at a tertiary children's hospital.
- Trial name
- ROB-PED (NCT07438704)
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Inguinal Hernia, Postoperative Pain
Lumbar ESP Block Versus TAP Block for Postoperative Pain Control in Children Undergoing Open Inguinal Hernia Repair
This study evaluates two ultrasound-guided nerve block techniques-Erector Spinae Plane Block (ESPB) and Transversus Abdominis Plane (TAP) block-for pain relief in children undergoing elective open inguinal hernia repair.
- Trial name
- NCT07916233
- Testing
- Ultrasound-guided Lumbar Erector Spinae Plane Block (ESPB), Ultrasound-guided Transversus Abdominis Plane (TAP) Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Attention Deficit Hyperactivity Disorder
Development of a Game-supported Intervention
The investigators will develop and pilot test an innovative computer-assisted behavior intervention (CABI) for middle school students with attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT05048043
- Testing
- Computer-assisted Behavior Intervention, Challenging Horizons Program
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- East Carolina University
Prodromal Schizophrenia, Prodromal Psychosis
Aripiprazole Treatment of the Prodrome
The RAP Program is conducting a research study of the antipsychotic medication Aripiprazole. This drug has been approved for treating symptoms associated with schizophrenia and is associated with fewer side effects.
- Trial name
- NCT00169949
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Coronary Artery Disease
Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention Study
This study investigates potential protective effect of atorvastatin pre-treatment in patient with stable coronary artery disease undergoing percutaneous coronary intervention (PCI).
- Trial name
- TIPS (NCT00469326)
- Testing
- Atorvastatin
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital, Motol
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Crohn Disease
The Intensive Post Exclusive Enteral Nutrition Study
Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms.
- Trial name
- iPENS (NCT04225689)
- Testing
- CD-TREAT diet
- Where
- 5 sites in United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Cerebral Palsy, Hemiplegia
Effect of Baby-CIMT in Infants Younger Than 12 Months
A randomized control trial investigating if an early intervention program of modified Constraint Induced Movement Therapy for babies, Baby-CIMT, performed before 12 months of age will improve hand function in children with risk…
- Conditions
- Cerebral Palsy, Hemiplegia, Children
- Trial name
- B-CIMT (NCT01864811)
- Testing
- Baby-CIMT, Baby-Massage
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Karolinska Institutet
Childhood Obesity
The Optimising Family Engagement in HENRY (OFTEN) Study
This study will test whether parent engagement (recruitment, attendance) in a Childhood obesity prevention programme (HENRY) can be improved in local authorities randomised to receive an Optimisation intervention (in addition to…
- Trial name
- OFTEN (NCT02675699)
- Testing
- Optimisation + HENRY, HENRY as standard
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Coronary Artery Disease, Myocardial Infarction
Disrupt CAD III With the Shockwave Coronary IVL System
The study design is a prospective, multicenter, single-arm, global IDE study to evaluate the safety and effectiveness of the Shockwave Medical Coronary Intravascular Lithotripsy (IVL) System in de novo, calcified, stenotic…
- Trial name
- NCT03595176
- Testing
- Lithotripsy
- Where
- 48 sites in United States, France and 2 more
- Volunteers
- 431 people
- Sponsor
- Shockwave Medical, Inc.
Multiple Trauma, Massive Bleeding
Evaluation of the TICCS Capacity to Identify Trauma Patients With Acute Coagulopathy and Massive Bleeding
A prospective single-centre non-comparative non-interventional open study has been designed to validate, in a target number of 100 trauma patients, the correlation between TICCS evaluated on the site of injury and…
- Conditions
- Multiple Trauma, Massive Bleeding, Early Complication of Trauma
- Trial name
- NCT02132208
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Albinism, Oculocutaneous Albinism
Vision Response to Dopamine Replacement
The purpose of the study is to evaluate and document physiologic and functional changes in visual performance and retinal function of patients diagnosed with albinism (a dopamine deficiency state) following a trial of oral…
- Trial name
- NCT01663935
- Testing
- Levodopa/carbidopa
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Hematological Malignancies, Cancer
Cologne Cohort of Neutropenic Patients (CoCoNut)
The Cologne Cohort of Neutropenic Patients (CoCoNut) is a non-interventional cohort study assessing risk factors, interventions, and outcome of immunosuppressed patients with or without opportunistic infections.
- Conditions
- Hematological Malignancies, Cancer, Chemotherapy, Neutropenia
- Trial name
- CoCoNut (NCT01821456)
- Testing
- Antiinfectives
- Where
- Germany
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University Hospital of Cologne
Literacy
Occupational Therapy-based Literacy Intervention and Classroom Based Literacy Intervention
The purpose of this study is to determine the impact of a literacy focused occupational therapy intervention program versus standard classroom-based reading intervention on reading engagement and reading achievement in elementary…
- Trial name
- NCT03975972
- Testing
- Occupational Therapy Based Literacy Intervention
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Periodontal Diseases
Interactive School-Based Oral Health Education Program to Reduce Periodontal Disease in Palestinian Adolescents
The goal of this intervention study was to evaluate the effectiveness of a two-month interactive school-based oral health education program in reducing periodontal disease and improving oral health behaviors among 15-year-old…
- Trial name
- ISBOHE-PD (NCT07055932)
- Testing
- "Interactive Oral Health Education Program"
- Where
- Palestinian Territories
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Hemophilia A With Inhibitor, Hemophilia B With Inhibitor
Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSeven
This study evaluates the immunogenicity of the biosimilar rFVIIa (AryoSeven) in subjects receiving AryoSeven in real-life clinical practice.
- Conditions
- Hemophilia A With Inhibitor, Hemophilia B With Inhibitor, Factor VII Deficiency, Glanzmann's Thrombasthenia
- Trial name
- NCT03372993
- Where
- 2 sites in Iran
- Volunteers
- 200 people
- Sponsor
- AryoGen Pharmed Co.
Physical Fitness, Adiposity
Effects of a 10-Week Zumba Program on Adiposity and Flexibility in 8-Year-Old Children
The purpose of this study is to investigate the effects of a 10-week Zumba dance-based exercise program on body fat (adiposity) and flexibility in healthy 8-year-old children.
- Trial name
- NCT07512349
- Testing
- Zumba Dance-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ege University
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