Clinical trials: Interventional Study
Open-angle Glaucoma (OAG)
5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
This study is designed to collect clinical data at 3, 4, and 5 years postoperatively for participants who completed the CREST Study without having secondary IOP-lowering surgery in the study eye(s).
- Trial name
- CREST-XT (NCT07480343)
- Testing
- CycloPen Micro-Interventional Cyclodialysis System, CycloPen Micro-Interventional Cyclodialysis System Post Cataract
- Where
- 10 sites in United States
- Volunteers
- 250 people
- Sponsor
- Iantrek, Inc.
Type 1 Diabetes Mellitus, Parent-Child Relations
Feasibility Study of a Behavioral Parent Intervention to Support Self-management in Pediatric Typ 1 Diabetes
This study investigates feasibility and preliminary effects of a new behavioral parent intervention that aims to support and improve pediatric diabetes self-management
- Conditions
- Type 1 Diabetes Mellitus, Parent-Child Relations, Self-management, Behavioral Intervention
- Trial name
- NCT06599840
- Testing
- Parent intervention
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Iodine Deficiency
The Next Step Towards the Elimination of Iodine Deficiency and Preventable Iodine-related Disorders in Europe
In the EUthyroid2 intervention, measures are being developed and implemented in educational settings across the UK, Germany, Slovenia, the Republic of Cyprus, Bangladesh, and Pakistan to effectively raise awareness of the risks…
- Trial name
- EUthyroid2 (NCT06801691)
- Testing
- Experimental: Intervention group
- Where
- 6 sites in Bangladesh, Cyprus and 4 more
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- EUthyroid
Fatty Liver
A Pilot Study to Explore the Role of Gut Flora in Fatty Liver
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding Fatty Liver.
- Trial name
- NCT04160949
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Congenital Bleeding Disorder, Haemophilia A With Inhibitors
Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors When Undergoing Surgery
This study is conducted in Japan. The aim of this non-interventional study is to investigate the safety and effectiveness of treatment with eptacog alpha (NovoSeven®) when undergoing surgery under normal clinical practice…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
- Trial name
- NCT01579968
- Testing
- eptacog alfa (activated)
- Where
- Japan
- Volunteers
- 86 people
- Sponsor
- Novo Nordisk A/S
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
The primary focus of this research proposal is to examine the efficacy of a nursing care protocol in preventing the occurrence of deep vein thrombosis (DVT) in patients undergoing on-pump cardiac surgery.
- Conditions
- On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis, DVT Prevention
- Trial name
- DVT (NCT07347652)
- Testing
- IPC devices facilitate venous return by simulating the physiological effects of muscle contraction, reducing venous stasis.
- Where
- Cyprus
- Volunteers
- 67 people
- Sponsor
- Near East University, Turkey
Any Cancer Diagnosis
A Cognitive- Behavioral Play Intervention for Siblings of Children Diagnosed With Cancer
The goal of this study is to determine whether a brief (three 20-30 minute session) cognitive-behavioral play intervention will improve coping skills and adjustment for siblings of children diagnosed with cancer.
- Trial name
- NCT01704885
- Testing
- Play Intervention, Questionnaires
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Edentulous
a 10-year Follow-up Study of a Randomized Clinical Trial
In this study, the investigators propose a 10-year follow up study of participants in a randomized clinical trial to compare the oral health-related quality of life (OHRQoL), as well as general and related satisfaction of…
- Trial name
- NCT02289443
- Testing
- complete denture
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Nihon University
Asthma, Psychosocial Stress
Stress Management Intervention in Inner City Adolescents With Asthma
The study will utilize a stress management program delivered over 10 sessions that is hypothesized to result in decreased stress levels and improved coping strategies in an inner city adolescent asthma population.
- Trial name
- SIPIICAA (NCT01445015)
- Testing
- Stress management program, Peer viewed movies
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anemia, Blood Transfusions, Autologous
A Study to Evaluate the Safety and Effectiveness of Epoetin Alfa Versus Placebo in Facilitating the Presurgical Collection of Blood to be Used for Self-donation During Surgery on the Spine, Hip, or Knee.
The purpose of this study is to evaluate the safety and effectiveness of epoetin alfa at doses of 150, 300, or 600 units per kilogram of body weight versus placebo in facilitating presurgical collection of blood for self-donation…
- Conditions
- Anemia, Blood Transfusions, Autologous, Orthopedic Procedures
- Trial name
- NCT00270140
- Testing
- epoetin alfa
- Volunteers
- 17 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Marfan Syndrome
Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.
Marfan syndrome (MFS) is a rare genetic disease (1/5000) characterized by the association of ocular impairment, cardiovascular disease and musculoskeletal disease.
- Trial name
- Marfanpower (NCT03236571)
- Testing
- Rehabilitation program
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Toulouse
Motor Skills Disorders, Autism Spectrum Disorder
DCD & ASD Imaging Intervention Study
Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that affects a child's ability to learn motor skills, such as tying shoelaces, learning to print, or riding a bicycle (APA 2013).
- Trial name
- NCT04119492
- Testing
- CO-OP Treatment Group
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Motor Activity
A School-based Physical Activity Promotion Intervention in Children. PREVIENE Project
Background:The lack of physical activity and increasing time spent in sedentary behaviours during childhood place importance on developing low cost,easy-to-implement school-based interventions to increase physical activity among…
- Trial name
- PREVIENE (NCT03185338)
- Testing
- Active commuting to/from school, Active Physical Education lessons, Active school recess
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
HIV/AIDS
Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study
This study will refine and pilot test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention in a single-arm pilot trial.
- Trial name
- NCT07298785
- Testing
- Peer-led Dynamic Choice HIV Prevention (DCP) intervention
- Where
- Uganda
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Premature
Feasibility Study of SPEEDI
The proposed feasibility study will evaluate the investigators ability to conduct a clinical trial of a novel intervention (SPEEDI) which addresses a striking gap in the literature.
- Trial name
- SPEEDI (NCT01889108)
- Testing
- SPEEDI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Parkinson Disease
A Study of Equfina® on the Incidences of Adverse Drug Reactions in Participants With Parkinson's Disease (Including Participants With Hepatic Impairment)
The purpose of the study is to investigate the incidences of psychiatric symptoms (example, hallucinations), somnolence and sudden onset of sleep, dyskinesia, and retinal degeneration-related events during treatment with Equfina…
- Trial name
- NCT04724109
- Testing
- Equfina
- Where
- 2 sites in Japan
- Volunteers
- 1,088 people
- Sponsor
- Eisai Co., Ltd.
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
OT Intervention Via Telehealth for Children With ASD and ADHD
This study aims to measure the impact of a telehealth-based model of occupational therapy (OT) treatment on clinical outcomes for children with autism spectrum disorder (ASD) and/or attention deficit hyperactivity disorder…
- Trial name
- NCT03957993
- Testing
- Occupational Therapy via Telehealth, Standard of Care Occupational Therapy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Peer-enhanced Intervention to Support Teen Weight Loss
The purpose of this study is to determine whether adding a peer-based intervention based on an outward bound model is more effective than a standard behavioral weight intervention for helping adolescents lose weight.
- Trial name
- NCT00285558
- Testing
- CBT with peer-enhanced activities, CBT with supervised aerobic exercise
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pain and Anxiety, Dislocation
Virtual Reality in the Management of Painful or Anxiety-provoking Procedures in Emergency Departments
Study and evaluate the effectiveness of virtual reality in pain management.
- Conditions
- Pain and Anxiety, Dislocation, Suture
- Trial name
- VR (NCT06425835)
- Testing
- VR device
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Hemophilia A
Non-interventional Observation of Practical Implementation, Efficacy and Safety of Continuous Infusion With KOGENATE Bayer in Surgery
The objective of this international post-marketing surveillance study is to collect data on the efficacy and safety of continuous infusion with KOGENATE Bayer in surgery.
- Trial name
- NO PEACKS (NCT00922597)
- Testing
- Recombinant Factor VIII (Kogenate FS, BAY14-2222)
- Where
- 7 sites in Austria, Germany and 5 more
- Volunteers
- 26 people
- Sponsor
- Bayer
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