Clinical trials: Interventional Study
Bicycling, Knowledge
Study to Improve Adolescent Bicycling Safety
This cluster randomized controlled trial will evaluate a community-based bicycle safety education program with and without an in-person parent training component.
- Conditions
- Bicycling, Knowledge, Adolescent, Self Efficacy
- Trial name
- NCT05265689
- Testing
- Bike Club, Bike Club Plus
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Cara J. Hamann
Neonatal Resuscitation, Heart Rate Assessment
Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
NeoTapAdvancedSupport (NeoTapAS) is a free-of-charge mobile application that showed good accuracy in HR estimation. This study aims to evaluate the impact of NeoTapAS on timing of HR communication and of resuscitation…
- Trial name
- NCT03730025
- Testing
- Auscultation plus NeoTapAS, Auscultation without NeoTapAS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Cerebral Palsy, Spastic, Rehabilitation
A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection
To establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (CIMT) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.
- Trial name
- NCT04179682
- Testing
- 40-hour constraint-induced movement therapy
- Volunteers
- 6 people
- Sponsor
- Changhua Christian Hospital
Adult Cancer Survivors, Adult Cancer Patients
Holistic Evaluation of Approaches to Long-term Health & Survivorship
This study aims at investigating behaviors of cancer patient regarding complementary and alternative medicine (CAM) with mixed methodology.
- Trial name
- HEALTHS (NCT07745205)
- Testing
- Interventional mixed-methods evaluation of cancer patient's behaviour regarding CAMs (focus groups), Quantitative evaluation of cancer patient's use of CAM's
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Anemia, Iron Deficiency Anemia
Local Culture-Based Nutrition Education Intervention on Iron Supplement Tablets (IST) Consumption Compliance in Female Adolescents at Ogan Komering Ilir Regency: A Quasi-Experimental Protocol Study
The goal of this clinical trial is to test the impact of a local culture-based nutritional education intervention on IST consumption compliance among female adolescents in the Ogan Komering Ilir Regency.
- Trial name
- NCT06009575
- Testing
- Iron Supplement Tablets
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Sriwijaya
Hemophilia A
BAX 802 in CHA With Inhibitors
The purpose of this study is to evaluate the efficacy and safety of BAX 802 in males with congenital hemophilia A (CHA) with inhibitors who are undergoing major or minor elective surgical, dental, or other invasive procedures.
- Trial name
- CHAWI (NCT02895945)
- Testing
- Antihemophilic Factor (Recombinant), Porcine Sequence (BAX 802)
- Where
- 24 sites in United States, Bulgaria and 10 more
- Volunteers
- 8 people
- Sponsor
- Baxalta now part of Shire
Anxiety, Autism
Molehill Mountain Feasibility Study.
Up to half of autistic people experience anxiety symptoms, which can have a significant impact on everyday wellbeing. However, there are currently very few effective, evidence-based interventions to support autistic people in…
- Trial name
- NCT05302167
- Testing
- Molehill Mountain app
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College London
Low Cardiac Output Syndrome, Cardiac Surgical Procedures
Prophylactic Use of Milrinone After Congenital Heart Surgery in Infants
This randomized, multi-center, double-blinded, placebo-controlled study is designed to evaluate the efficacy and safety of milrinone compared with placebo in participants after corrective surgery for congenital heart disease.
- Conditions
- Low Cardiac Output Syndrome, Cardiac Surgical Procedures, Infant
- Trial name
- NCT03823781
- Testing
- Milrinone, Normal saline
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Shanghai Children's Medical Center
Crohn's Disease
An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan
Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world.
- Trial name
- NCT06023030
- Where
- 104 sites in Japan
- Volunteers
- 240 people
- Sponsor
- AbbVie
Acute Pancreatitis
Invasive Intervention of Local Complications of Acute Pancreatitis
Strategies for invasive intervention in acute pancreatitis include sequential or combined use of multiple drainage and debridement modalities.
- Trial name
- NCT06023771
- Testing
- Invasive intervention for acute pancreatitis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Loneliness, Social Isolation
The Feasibility, Acceptability and Preliminary Efficacy of a Group Intervention to Reduce Loneliness
Severe loneliness is a large and growing clinical and societal problem. Although there are interventions for loneliness, elevated levels often remain.
- Trial name
- NCT05831813
- Testing
- Goal-Based Cognitive Behavioural Intervention
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- University of Amsterdam
Infant Nutrition, Cognitive Development
Efficacy of a Nutrient Blend in Improving Neurocognitive and Behavioral Outcomes in Infants: a Randomized, Controlled, Intervention Study
The purpose of this study is to demonstrate the efficacy of the nutrient blend in a starter infant formula (IF) and follow up infant formula (FUF) in improving the neurocognitive and behavioural outcomes among formula-fed infants…
- Trial name
- NCT05310396
- Testing
- Experimental formula, Control Formula
- Where
- Philippines
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Child Wellbeing, Adolescent Health
Promoting Wellbeing: The Five Ways at School Intervention
The aim of this study is to develop a teaching material built on the Five Ways to Wellbeing and investigate its effects on wellbeing and mental health among school pupils aged 10 to 16 years in Moss municipality, Norway.
- Conditions
- Child Wellbeing, Adolescent Health, Quality of Life
- Trial name
- 5Ways@School (NCT06144502)
- Testing
- 5Ways@School
- Where
- Norway
- Volunteers
- 2,476 people
- Sponsor
- Moss Kommune
Post-traumatic Stress Disorder, Leadership
Testing the LOCI Intervention
The project will develop knowledge on how managers can lead the implementation of practices that have proven to be effective for post-traumatic stress disorders (PTSD) in child and adult specialized mental health services.
- Trial name
- NCT03719651
- Testing
- LOCI, EMDR, CT-PTSD
- Where
- Norway
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Aortic Aneurysm
Patient Specific Biomechanical Modeling of Abdominal Aortic Aneurysm to Improve Aortic Endovascular Repair
This project is aiming at the integration of a biomechanical computer program with a guidance code to simulate the endovascular repair (EVAR) procedure of abdominal aortic aneurysm (AAA).
- Trial name
- AAA2D3DIII (NCT03481075)
- Testing
- Biomechanical computer program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Prostate Cancer
Study to Evaluate the Presence of Lower Urinary Tract Symptoms (LUTS) in Prostate Cancer Patients Scheduled to Receive Luteinizing Hormone Releasing Hormone (LHRH) Analogues
The intention of this study is to investigate how many patients with prostate cancer, planned to be treated with LHRH analogues without history of surgery or radiotherapy, are suffering from LUTS.
- Trial name
- ANALUTS (NCT02542501)
- Where
- 32 sites in Portugal, Spain
- Volunteers
- 470 people
- Sponsor
- Ipsen
Physical Disability, Cognitive Dysfunction
Evaluation of mediVR-KAGURA Guided Therapy
The objective is to evaluate mediVR-KAGURA guided therapy for the treatments of physical and cognitive dysfunctions regardless of baseline disease in a prospective interventional design.
- Trial name
- NCT04562662
- Testing
- mediVR KAGURA
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Japan Society of Clinical Research
Gaucher Disease
Home Therapy With VPRIV in Gaucher's Disease
The purpose of this study is to proof increasing patient satisfaction and preservation of quality of life in patients with Gaucher's Disease receiving their enzyme replacement therapy with VPRIV (Velaglucerase alfa)at their home…
- Trial name
- NCT01356537
- Where
- 11 sites in Austria, Germany
- Volunteers
- 34 people
- Sponsor
- Shire
Obesity, Overweight
Impact of a Childhood Obesity Intervention for African American Families
The purpose of this study is to evaluate the impact on body mass index (BMI) of a 5-session childhood obesity intervention for African American families among children aged 5-12 years.
- Trial name
- NCT02044731
- Testing
- Active and Healthy Families
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Major Depressive Disorder (MDD), Probiotic Intervention
Sertraline Combined With Multi-Strain Probiotics for Adolescent Depression
The objective of this clinical trial is to evaluate the efficacy and safety of sertraline combined with multi-strain probiotics in adolescents aged 12-18 with major depressive disorder.
- Trial name
- NCT07645157
- Testing
- Sertraline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
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