Clinical trials: Interventional Study
Exercise, Diet Interventions
Multimodal Intervention for Early Chronic Kidney Disease in Young People: Dysbiosis and Inflammation (CKD)
Chronic kidney disease (CKD) is a progressive condition associated with substantial morbidity, mortality, and healthcare costs. Early detection and timely intervention are critical to modify disease trajectory, particularly in…
- Conditions
- Exercise, Diet Interventions, Symbiotic, CKD Stage 1
- Trial name
- CKD (NCT07483697)
- Testing
- symbiotic
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
Health Behavior
A Brief Outpatient Problem-solving Intervention to Promote Healthy Eating and Activity Habits in Adolescents
The purpose of this study is to refine, evaluate the feasibility, and to estimate the effect of the "healthy Living Study," a brief outpatient problem-solving intervention to promote healthy eating and activity habits in…
- Trial name
- NCT01699958
- Testing
- Problem-solving intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cerebral Palsy
EARLY Intervention in Parent-professional Cooperation in Cerebral Palsy
Cerebral Palsy (CP) is the most common motor disability in children. It is due to damage that occurs during brain development in the fetus or infant.
- Trial name
- PRECOP (NCT06180291)
- Testing
- PRECOP program
- Where
- 8 sites in France
- Volunteers
- 66 people
- Sponsor
- Hospices Civils de Lyon
Dengue, Vector Borne Diseases
Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating
Effective control of Aedes aegypti mosquitoes in breeding sites with high reproductive rates could have a major impact on reducing arbovirosis in endemic communities.
- Conditions
- Dengue, Vector Borne Diseases, Arbovirus Infections, Zika
- Trial name
- NCT06268691
- Testing
- Insecticide Coating INESFLY
- Where
- 2 sites in Colombia, Germany
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Rocio Cardenas Sanchez
Hemophilia A, Hemophilia B
Virtual Reality for Hemophilia
Children with hemophilia are exposed to intravenous (IV) procedures that cause pain/anxiety and distraction methods can be employed to improve the patient experience.
- Trial name
- NCT03507582
- Testing
- Virtual Reality Distraction, Standard of Care Distraction
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nationwide Children's Hospital
Surgical Procedures, Operative
The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.
Animal studies suggest general anaesthetics harm the developing brain. It is unclear if these findings are relevant to humans but the issue has become a major concern.
- Trial name
- NCT02353182
- Testing
- Dexmedetomidine, Remifentanil, Bupivacaine
- Where
- 6 sites in United States, Australia and 1 more
- Volunteers
- 60 people
- Sponsor
- Murdoch Childrens Research Institute
Pediatric Surgical Procedures, Adult Surgical Procedures
A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures
The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical…
- Conditions
- Pediatric Surgical Procedures, Adult Surgical Procedures, Adult Gynecological Procedures, Adult Urological Procedures
- Trial name
- NCT06608485
- Testing
- HARMONIC 700 Shears
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 173 people
- Sponsor
- Ethicon Endo-Surgery
Borderline Personality Disorder, Sleep Disturbance
Real-time Experiences With Sleep Training Study
Borderline personality disorder (BPD) is a serious mental illness that often first emerges in adolescence. Effective treatments are typically expensive, lengthy, and intense (e.g., Dialectical Behavior Therapy).
- Trial name
- REST (NCT04507308)
- Testing
- Single-session sleep intervention drawn from principles of the TSC-youth protocol
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- University of Utah
Sleep Problems, Behavioural Insomnia of Childhood
The ABCs of SLEEPING: Effectiveness Study
This trial will examine the effectiveness of a mobile applicable intervention called the "ABCs of SLEEPING". This intervention provides parents with prioritized/customized sleep recommendations and a sleep report based on their…
- Trial name
- NCT05072548
- Testing
- The ABCs of SLEEPING
- Where
- Canada
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Self Harm
Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study
The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions.
- Trial name
- NCT06317155
- Testing
- Occupational therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Carcinoma
A Non Interventional Study With Paclitaxel Onkovis (Paclitaxel) Utilized for the Treatment of Cancer
The main purpose of this observational study with Paclitaxel is to determine the number of treatment cycles and the quantity of Paclitaxel onkovis needed therefore under the special circumstance of ambulant chemotherapy.
- Trial name
- NCT01668108
- Where
- 5 sites in Germany
- Volunteers
- 770 people
- Sponsor
- Onkovis GmbH
Maternal; Procedure
Total Placenta Previa Associated With the Placenta Accreta Spectrum.
To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.
- Trial name
- PAS (NCT06219564)
- Testing
- Peripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Severe Hemophilia A Without Inhibitor
A Study on the Bone-health Effectiveness of Applying Recombinant Factor VIII Fc (rFVIIIFc) to Patients With Hemophilia A (Prototype A)
Study Objectives* 1. Provide a systematic evaluation of the treatment outcomes in patients with hemophilia A 2. Emphasize the importance and clinical benefits of rFVIII-Fc in joint and bone health. 3.
- Trial name
- NCT05981274
- Testing
- serum biomarker.
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Cardiovascular Diseases, Heart Diseases
Dietary Intervention Study in Children (DISC)
To assess the feasibility, acceptability, efficacy, and safety of dietary intervention in free-living children ages 8-10 with elevated low density lipoprotein cholesterol levels.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypercholesterolemia
- Trial name
- NCT00000459
- Testing
- diet, fat-restricted
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Full Thickness Rotator Cuff Tear
Enhanced Function and Quality of Life Following 5 Months of Exercise Therapy for Patients With Rotator Cuff Tears
This study aims to evaluate the effect of 5 months of exercise therapy for patients with irreparable rotator cuff tears.
- Trial name
- NCT02740946
- Testing
- Exercise therapy
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Bone Lesion
Interventional Radiology in Bony Lesions
To explore the capability of the interventional radiology techniques in management of the painful bony lesions .
- Trial name
- NCT05738941
- Testing
- radiofrequency ablation, angioembolization
- Volunteers
- 50 people
- Sponsor
- Assiut University
Colorectal Adenoma, Colorectal Cancer Control and Prevention
6-year Follow-up Data After the Berberine Intervention Trial
Colorectal cancer (CRC) is a common malignancy of the digestive tract, which constitutes a major public health burden. Almost 90% of CRC cases progress from precursor adenomatous polyps through adenoma-carcinoma sequence.
- Conditions
- Colorectal Adenoma, Colorectal Cancer Control and Prevention, Colorectal Polyps
- Trial name
- NCT06629051
- Testing
- Berberine Hydrochloride
- Where
- China
- Volunteers
- 891 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cognition - Other
Cognition Intervention Study Dortmund
Major aim of this study is to add scientifically proven insights into cognitive effects of meals to the existing recommendations for school meals in Germany.
- Trial name
- CogniDO (NCT01401153)
- Testing
- Skipping lunch
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Stem Cell Transplantation
Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Feasibility Study
The goal of this clinical trial is to test the feasibility and acceptability of the Bright IDEAS problem-solving skills training (PSST) intervention for parents of children undergoing hematopoietic stem cell transplantation…
- Trial name
- NCT07219524
- Testing
- Bright Ideas Problem-Solving Skills Training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Children's Hospital Los Angeles
Healthy
Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
- Trial name
- NCT00960596
- Testing
- Health promotion and health education for smoking habits
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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