Clinical trials: Intestinal Diseases, Parasitic
Helminthiasis, Amoebiasis
Study to Evaluate Efficacy and Safety of a Double Treatment Plan Using a Combination of Mebendazole and Quinfamide for Treating Intestinal Helminthiasis and Amebiasis in the Mexican Population
The purpose of this study is to assess the efficacy and safety of the combination of mebendazole plus quinfamide for the treatment of intestinal helminthiasis and amoebiasis in Mexican population.
- Trial name
- NCT02385058
- Testing
- Mebendazole, Quinfamide
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Janssen-Cilag Ltd.
Dysentery Amebic
Immunochromatography Versus Microscopy for Diagnosis of Entamoeba Histolytica/Dispar Infection.
Amoebiasis, an infection by the protozoan parasite Entamoeba histolytica is globally considered as the third leading parasitic cause of human mortality besides malaria and schistosomiasis. It is estimated that E.
- Trial name
- NCT04759937
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Intestinal Diseases, Parasitic
Postpartum Deworming: Improving Breastfeeding and Optimizing Infant Growth
Women of reproductive age are considered a high-risk group for worm infections by the World Health Organization. Maternal infection and anemia contribute to infant malnutrition by affecting milk quality and quantity, and duration…
- Trial name
- NCT01748929
- Testing
- Albendazole
- Where
- Peru
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Schistosomiasis
Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST)
An open label, randomized controlled trial of single vs. multiple treatments of praziquantel in intestinal African schistosomiasis in Côte d'Ivoire This study aims to determine the efficacy of repeated (up to four times)…
- Trial name
- RePST (NCT02868385)
- Testing
- 4x Praziquantel, 1x Praziquantel
- Where
- Côte d’Ivoire
- Volunteers
- 167 people
- Sponsor
- Leiden University Medical Center
Liver Cirrhosis
Pattern of Intestinal Parasitic Infection Among Cirrhotic Patients in Sohag University Hospital
Chronic hepatic illness is one of the most serious health issues . Liver cirrhosis as the latest phase of chronic liver disease causes a disorder called cirrhosis-associated immune dysfunction syndrome (CAIDS) .
- Trial name
- NCT05856721
- Testing
- stool analysis
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Parasite IBS IBD
Role of Parasitic Infection in Inflammatory Bowel Disease and Irritable Bowel Syndrome
Role of parasitic infection in Inflammatory bowel disease and Irritable bowel The burden of the parasitic disease is in-direct relation with the health and nutritional status of the host, inducing not only parasite-specific…
- Trial name
- NCT04760600
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intestinal Helminthiasis
Impact of Health Education on School Children
There is a sever lack in application of health education intervention for Soil Transmitted Disease (STH) in rural communities and in school children among Orang Asli in Pahang in Malaysia, and also there is a lack of information…
- Trial name
- NCT01640626
- Testing
- Health Education package
- Where
- Malaysia
- Volunteers
- 317 people
- Sponsor
- University of Malaya
Cryptosporidiosis, HIV Infections
A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3
To determine the effectiveness of oral paromomycin sulfate for 21 days compared to placebo in the treatment of cryptosporidiosis in patients with HIV infection. To evaluate the safety of oral paromomycin at two different doses.
- Trial name
- NCT00000771
- Testing
- Paromomycin sulfate
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 68 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Amebiasis, Cryptosporidiosis
Parasitic Infections of the Gastrointestinal Tract
This protocol offers diagnosis and standard medical treatment for various parasitic gastrointestinal infections. Gastrointestinal parasites are either worms (helminths) or one-celled animals called protozoans which live in the…
- Conditions
- Amebiasis, Cryptosporidiosis, Giardiasis, Parasitic Disease
- Trial name
- NCT00001162
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cryptosporidiosis, HIV Infections
A Study of Spiramycin in the Treatment of Patients With AIDS-Related Diarrhea
To determine the safety and effectiveness of intravenous spiramycin in patients with AIDS-related cryptosporidial diarrhea. Spiramycin, a macrolide antibiotic, has been studied in the United States for the treatment of…
- Trial name
- NCT00000980
- Testing
- Spiramycin
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Rhone-Poulenc Rorer
HIV Infections, Protozoan Infections
Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts
In this two-year study, we will target two high risk groups, including MSM of HIV-infected and those of non-HIV-infected. We will avail the serodiagnosis to detect the potential amebic carriers in both groups; and use microscopy…
- Trial name
- NCT00630162
- Testing
- amoeba
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Helminth Infection
Intestinal Microbiome Post-Azythromycin/Albendazole Treatment
Molecular testing of the gut microbiome and enteric pathogens is rapidly moving beyond targeted PCR testing to next generation sequencing techniques.
- Trial name
- NCT03032042
- Testing
- Azithromycin, Albendazole, Delayed treatment
- Where
- Ethiopia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Trichuriasis, Ascariasis
Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration
The aim of this randomized controlled trial is to provide evidence on the efficacy and safety of co-administered moxidectin and albendazole compared to co-administered ivermectin and albendazole, and to assess the efficacy of the…
- Conditions
- Trichuriasis, Ascariasis, Hookworm Infections, Helminthes; Infestation, Intestinal
- Trial name
- NCT04700423
- Testing
- moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL]
- Where
- Tanzania
- Volunteers
- 536 people
- Sponsor
- Jennifer Keiser
Giardiasis
Impact of Anti-Giardia and Antihelmintic Treatment on Infant Growth in Bangladesh
This longitudinal study aimed to assess whether regular anti-Giardia and antihelmintic treatment improved growth and small intestinal mucosal function of rural Bangladeshi infants.
- Trial name
- NCT00607074
- Testing
- Anti-Giardia and antihelmintic treatment (secnidazole or albendazole), Anti-Giardia treatment only (secnidazole or albendazole)
- Where
- Bangladesh
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Intestinal Diseases, Helminthiasis
Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora
Albendazole is a main anti-helminth, however there is a lack of data regarding its efficacy in the school children population. The aim of this study is to evaluate the efficacy of the albendazole one versus two and three doses…
- Trial name
- NCT01192802
- Testing
- albendazole
- Where
- Gabon
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Albert Schweitzer Hospital
Intestinal Parasitic Infection
Evaluation of Feconomics for Diagnosis of Intestinal Parasitic Infections
People of all ages are affected by intestinal parasitic infections(IPIs) ; however, children are the most commonly affected, which is linked to their poor hygienic practices, and weak immune status.
- Trial name
- NCT05360472
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Blastocystis Infections
Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis
Blastocystis is an anaerobic unicellular protozoal parasite infecting the gastrointestinal tract of humans and a wide range of animals.
- Trial name
- NCT05580393
- Testing
- RFLP analysis of SSU rRNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pregnancy Related, Pregnancy Loss
Microbiome and Malnutrition in Pregnancy
This study is being conducted to investigate how a mother's nutritional status and her gut microbiome during pregnancy contribute to the birth outcomes and health of her baby.
- Conditions
- Pregnancy Related, Pregnancy Loss, Pregnancy Complications, Pregnancy; Parasitic Disease
- Trial name
- MMIP (NCT04992104)
- Where
- 2 sites in Canada
- Volunteers
- 800 people
- Sponsor
- The Hospital for Sick Children
Cryptosporidiosis, HIV Infections
A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium
To determine the frequency of complete, marked, and partial clinical responses in patients with cryptosporidiosis treated with 6 weeks of NTZ versus 21 days of placebo.
- Trial name
- NCT00001081
- Testing
- Nitazoxanide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Intestinal Schistosomiasis
Schistosoma Mansoni Morbidity in Children Aged 1-5 Years
This study is about intestinal schistosomiasis, commonly known as bilharzia, in children aged 1-5 years along Lake Victoria shoreline.The children will be screened for S.
- Trial name
- NCT01901484
- Testing
- Praziquantel
- Where
- Uganda
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Makerere University