Clinical trials: Intestinal Flora
Infant Colic, Atopic Dermatitis
Use of Bifidobacterium Bifidum in Formula-Fed Infants With Colic, With or Without Atopic Dermatitis
The goal of this clinical trial is to evaluate whether daily probiotic supplementation with Bifidobacterium bifidum (Bifipral® drops) can reduce crying time in formula-fed infants aged 5 months or younger diagnosed with infant…
- Trial name
- NCT07754968
- Testing
- Bifidobacterium bifidum BFP19® and BFP29® (Bifipral®)
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Vitamin A Deficiency in Children
The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia
Based on recent nutrition survey (SEANUTS Malaysia) on a total of 3542 Malaysian Children aged between 6 months to 12 years old, 4.4% of the children had vitamin A deficiency.
- Trial name
- NCT03256123
- Testing
- red palm shortening group, palm shortening group
- Where
- Malaysia
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Breastfeeding, Dietary Intake
NUTRIPROTECT-Children Nutrition as a Protective or Health-risk Factor
Despite the intensive worldwide research dedicated to the nutrition and faecal microbiota, the studies that follow the link between the early nutrition, initial intestinal microbiota, and development of children over a longer…
- Conditions
- Breastfeeding, Dietary Intake, Health, Body Composition
- Trial name
- My-Milk-2 (NCT04076592)
- Where
- Slovenia
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Stunting
Gut Microbiota Stunted Children NTT
NTT Province is on the list of priority areas of high prevalence of stunting, Southwest Sumba, South Middle East, and Kupang district have a stunting prevalence of 36.2%, 34.5% and 48.1% respectively in 2020.
- Trial name
- NCT05119218
- Testing
- No Intervention
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bina Nusantara University
Anterior Crossbite
Evaluation of the Effect of Labio-Lingual Spring Hawley and Clear Aligners on Periodontal Health and Salivary Parameters
Objective: The aim of our study was to determine the effect of two different types of removable appliances on periodontal health, dental plaque colonization, as well as saliva, pH, flow rate, and buffering capacity of the…
- Trial name
- NCT06858033
- Testing
- Clear aligner, Labiolingual spring hawley
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ozge Gungor
Epilepsy
Precision Medicine in the Treatment of Epilepsy
Primary objectives: The purpose of this study is to identify single and composite biomarkers (from neuroimaging, electrophysiological, and non-imaging biological measures), clinical measures (from cognitive, psychometric, and…
- Trial name
- BDE (NCT05450822)
- Testing
- Levetiracetam, Levetiracetam Tablets, Lamotrigine tablet
- Where
- Denmark
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Revision Total Knee Arthroplasty, Osteoarthritis, Knee
Gut Microbiome in Orthopaedics: Revision Total Knee Arthroplasty
Many patients who receive knee replacement surgery must return for a revision (or repeat) surgery due to ongoing pain, stiffness, infection, or implant loosening.
- Trial name
- GUMBO (NCT06951477)
- Testing
- Revision Total Knee Arthroplasty
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Autism Spectrum Disorder, Functional Gastrointestinal Disorders
Low-FODMAP Diet and Probiotics: Effects on Gut, Behavior, and Microbiota in Children With Autism Spectrum Disorder
The goal of this clinical trial was to evaluate whether a low-FODMAP diet and probiotic supplements could reduce gastrointestinal (GI) symptoms and behavior problems in children with autism spectrum disorder (ASD) who also…
- Trial name
- NCT07086157
- Testing
- Probiotic, Low-FODMAP Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Acute Kidney Injury, Sepsis
Novel Biomarkers for Early Renal Injury in Children With Sepsis
Toxicosis often leads to multiple organ failure (MODS), with the kidney being the primary target organ due to its sensitivity to infection and ischemia.
- Conditions
- Acute Kidney Injury, Sepsis, Gout Flare
- Trial name
- NCT06197828
- Testing
- This study is an observational studie which have no intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Gastrointestinal Microbiome
Gut Microbiome Associated Study of Shanghai Infants With Jaundice
The purpose of this study is to evaluate the effect of probiotics on the gut microbiome of infants with jaundice.
- Trial name
- NCT03510936
- Testing
- Probiotics
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai 10th People's Hospital
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Ulcerative Colitis
Dynamic Changes of Gut Microbiota in UC After FMT
A prospective study to investigate the dynamic changes of gut microbiota through colonic transendoscopic enteral tubing in patients with ulcerative colitis after fecal microbiota transplantation.
- Trial name
- NCT03949257
- Testing
- colonic transendoscopic enteral tubing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Disorder of Stomach Function and Feeding Problems in Newborn, Feeding and Eating Disorders of Childhood
Effect of Early Oral Triple Viable Bifidobacterium Intestinal Flora in Preterm
Gut of newborn preterm is sterile, immediately by the mother and the surrounding environment from microbial colonization. As the effects of diet, intestinal flora is rapidly changed.
- Trial name
- NCT02060084
- Testing
- a control group, a probiotic-supplemented group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Hua
Constipation, Constipation Chronic Idiopathic
A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding chronic constipation
- Conditions
- Constipation, Constipation Chronic Idiopathic, Constipation - Functional, Constipation (Excl Faecal Impaction)
- Trial name
- NCT04148248
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Rosacea
Characterization of the Facial and Gut Microbiome in Rosacea
Questionnaires will be completed by each member of the twin set. A board-certified dermatologist will examine each member to categorize the type and severity of their rosacea.
- Trial name
- NCT03228927
- Testing
- comparison of twin A to twin B
- Volunteers
- 150 people
- Sponsor
- The Acne Cure Alliance
Prematurity; Extreme, Feeding Disorder Neonatal
Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
The central hypothesis of this clinical trial is that, in extremely preterm infants, protein-enriched human milk diets compared to usual human milk diets during the first 2 weeks after birth increase fat-free mass (FFM)-for-age Z…
- Conditions
- Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure
- Trial name
- NCT04325308
- Testing
- Protein-enriched human milk diet, Usual human milk diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Alabama at Birmingham
Childhood Obesity
Effect of POSTbiotics Supplementation on Microbiome in OBese Children: the POST-OB Study
This study evaluates the possible effect of postbiotics supplementation, combined with interventions aimed at improving diet and lifestyle, on gut microbiota composition and metabolite production.
- Trial name
- POST-OB (NCT04151823)
- Testing
- Vitamin D3, Immunofos, Promotion of physical activity
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milan
Diarrhea
Effects of Probiotic in Treatment of Persistent Diarrhea in Children
Persistent diarrhea is a common health problem worldwide, particularly in low-income countries. Approximately 3% to 20% of acute diarrhea episodes in children under 5 years of age become persistent diarrhea.
- Trial name
- NCT05812820
- Testing
- LiveSpo DIA30, LiveSpo CLAUSY, RO
- Where
- Vietnam
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Children's Hospital, Vietnam
Vitamin B 12 Deficiency
The Impact of Vitamin B12 Deficiency on Infant Gut Microbiota
Vitamin B12 plays important roles in DNA synthesis and neurological functions. Vitamin B12 deficiency is one of the most common micronutrient deficiencies and it has become increasingly more frequent in infants.
- Trial name
- NCT03365583
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marmara University
Epilepsy
Fecal Microbiota Transplantation for Epilepsy
Increasing evidences showed the microbiota effects on neuropsychiatric disorders. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation for epilepsy.
- Trial name
- NCT02889627
- Testing
- Fecal microbiota suspension
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Nanjing Medical University