Clinical trials: Intestine
Gut Microbiome
Gut Microbiome and Metabolic Pathways Changes in Vitiligo
Vitiligo is a chronic depigmenting autoimmune-associated skin disease and a growing psychological health concern because of its low quality of life.
- Trial name
- NCT03797417
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Celiac Disease, Ultrasound
Small Bowel Ultrasound and Antibody Levels in Celiac Disease Activity
This observational study aims to evaluate the relationship between small bowel ultrasound findings and tissue transglutaminase (tTG) antibody blood levels in assessing celiac disease activity.
- Conditions
- Celiac Disease, Ultrasound, Tissue Transglutaminase Antibody, Small Bowel Ultrasonography
- Trial name
- NCT07453589
- Testing
- Small bowel ultrasonography, Serological testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Necrotising Enterocolitis, Late-Onset Neonatal Sepsis
Characterization of Intestinal Microbiota Stability in Preterm Born Neonates
Study around very-low birthweight preterm infants at high risk of developing necrotizing enterocolitis (NEC) or late-onset sepsis (LOS).
- Trial name
- NEC (NCT04792918)
- Where
- 2 sites in Switzerland
- Volunteers
- 81 people
- Sponsor
- Emma Marie Caroline Slack
Crohn's Disease
Efficacy and Safety Study of Ontamalimab as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)
The purpose of this study is to evaluate the efficacy and safety of ontamalimab as maintenance treatment in participants with moderate to severe Crohn's disease (CD).
- Trial name
- CARMEN CD 307 (NCT03627091)
- Testing
- Ontamalimab
- Where
- 281 sites in United States, Argentina and 32 more
- Volunteers
- 40 people
- Sponsor
- Shire
Appendicitis
Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study
1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound for pediatric appendicitis.
- Trial name
- NCT02507674
- Testing
- ultrasound
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Inflammatory Bowel Diseases
Dapagliflozin in Patients With Ulcerative Colitis
The inflammatory bowel diseases (IBD) are described as complex, recurrent inflammatory conditions which are manifested as Crohn's disease (CD) and ulcerative colitis (UC).
- Trial name
- NCT05986136
- Testing
- Mesalamine, Dapagliflozin 10mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mostafa Bahaa
Very Preterm Infant, Necrotizing Enterocolitis (NEC)
Effects of Enteral Feeding Regimens on NEC, Mortality, and Neurodevelopment in Very Preterm Infants
The goal of this clinical trial is to evaluate whether supplementing with pasteurized donor human milk (pHDM) or preterm formula (PTF) when own mother's milk (OMM) is insufficient can improve outcomes in very preterm infants born…
- Trial name
- NCT07045844
- Testing
- Pasteurized Donor Milk for Insufficient Breastfeeding, Preterm Formula for Insufficient Breastfeeding, Routine fortification
- Where
- 24 sites in China
- Volunteers
- 2,324 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Intestinal Failure
Plasma Citrulline Level in Relation to Absorptive Surface
Correlation between determination of citrulline in plasma or dried blood Reference ranges for healthy children and babies Longitudinal follow-up of citrulline in preterm babies
- Trial name
- NCT00286039
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Immunity
A Clinical Study to Investigate the Effect of a Partially Hydrolysed Infant Formula With Added Synbiotics on Gut Microbiota Composition and Clinical Effectiveness in Infants at High Risk of Developing Allergy
With the rising prevalence of allergic diseases and the subsequent risk of developing other immune-related disorders, primary prevention of allergy has become a major priority.
- Trial name
- TEMPO (NCT03067714)
- Testing
- Infant formula with added synbiotics, Standard infant formula
- Where
- 59 sites in Belgium, Czechia and 11 more
- Volunteers
- 855 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Inflammatory Bowel Disease (IBD)
Gut Microbial Transplantation in Pediatric Inflammatory Bowel Diseases
Inflammatory bowel disease (IBD) is a chronic, debilitating, relapsing inflammatory disorder affecting the gastrointestinal tract which does not have a medical cure.
- Trial name
- GMT (NCT01560819)
- Testing
- Gut Microbial Transplantation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corewell Health West
Diet, Gluten-Free, Gluten-Sensitive Enteropathy
Non Coeliac Gluten Sensitivity in Children
Irritable Bowel syndrome (IBS) is a very frequent condition in children. Its management is difficult, often resulting in a persistence of chronical abdominal pain.
- Trial name
- NCT02895438
- Testing
- gluten
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Cancer, Bladder Cancer
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
The basic premise of this research proposal is to determine whether there is any significant association between germline polymorphisms and cancers of colon, bladder, breast, testicular, prostate, ovaries, kidney, lung, lymphoid…
- Conditions
- Breast Cancer, Bladder Cancer, Kidney Cancer, Colon Cancer
- Trial name
- NCT00579514
- Testing
- PCR/PCR/LDR Strategy
- Where
- United States
- Volunteers
- 21,081 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Type 1 Diabetes, Celiac Disease
Combined Antibody Screening for Celiac and Diabetes Evaluation
The CASCADE Study (Combined Antibody Screening for Celiac and Diabetes Evaluation) is an observational study whose primary goal is to show that population-based screening for advanced prediction of type 1 diabetes (T1D) and…
- Trial name
- CASCADE (NCT04677699)
- Testing
- Combined Risk Score
- Where
- United States
- Volunteers
- 64,410 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest Research Institute
Celiac Disease
Celiac Disease: Nutrition Education in Primary School
Celiac disease is a chronic immune-based intestinal pathology. Its prevalence is 1% and its incidence has increased in recent years.
- Trial name
- ZELIAKIDE (NCT05467865)
- Testing
- ZELIAKIDE
- Where
- Spain
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Crohn's Disease, Ulcerative Colitis
Non Invasive Characterization of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
Monocentric, prospective observational study to assess bowel inflammation in children with chronic inflammatory bowel disease (IBD) using multispectral optoacoustic tomography (MSOT).
- Conditions
- Crohn's Disease, Ulcerative Colitis, IBD
- Trial name
- PED_MSOT_IBD (NCT04650867)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Appendicitis
A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy.
A large retrospective study compared wound irrigation with antiseptic solution, with antimicrobial agent, and with normal saline in patients undergoing open appendectomy and concluded an evident superiority of antibiotic wound…
- Trial name
- NCT04332809
- Testing
- saline-gentamicin irrigation, saline irrigation
- Where
- Egypt
- Volunteers
- 208 people
- Sponsor
- Mansoura University
IBD
Stavanger University Hospital Inflammatory Bowel Disease Trial
The study aims at studying the outcomes of a protocol-based handling of newly diagnosed Inflammatory bowel disease ( IBD ) patients within a defined uptake area in Norway.
- Trial name
- SUSI (NCT01551563)
- Where
- Norway
- Volunteers
- 700 people
- Sponsor
- Helse Stavanger HF
Schistosomiasis, Anemia
Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal
SchistoVAN aims to study the role of schistosomiasis infection in the modulation of the immune response of children to childhood vaccine antigens, as well as the impact of this infection on their nutritional status and their…
- Conditions
- Schistosomiasis, Anemia, Underweight, Stunting
- Trial name
- SchistoVAN (NCT01553552)
- Where
- Senegal
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Biomedical Research Center EPLS
Colon Cancer
Endoscopic Therapy Or Surgery for Early Colon Cancer
The trial is a randomized head-to-head comparison of the benefits, harms and burdens of endoscopic full-thickness resection (eFTR), a novel, minimally invasive endoscopic treatment modality, for early colon cancer as compared to…
- Trial name
- ETHOS (NCT06940947)
- Testing
- eFTR, Surgery
- Where
- Poland
- Volunteers
- 434 people
- Sponsor
- Norwegian Department of Health and Social Affairs
Stem Cell Transplantation
Pipeline Integrating Gut Metagenome Data, Host Immunogenetic Characteristics and Clinical Gut Inflammatory Biomarkers
The combined analysis of microbiome, immunological parameters and host genetics in patients has potential for applying personalized approaches of prevention, diagnostics or therapy in the future.
- Trial name
- ImMiGeNe (NCT02940093)
- Testing
- Stem cell transplantation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.