Clinical trials: Intra-operative Complications
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Cervical Cancer
Analysis of Parametrial Lymph Nodes as Sentinel Nodes in Patients With Cervical Cancer
The goal of this clinical research study is to find out if the parametrial nodes are "sentinel" nodes (the lymph nodes believed to be the greatest risk for the spread of cancer) and if intraoperative lymphatic mapping can…
- Trial name
- NCT00631241
- Testing
- Single Photon Emission Computed Tomography, Intraoperative Lymphatic Mapping
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Perioperative Body Temperature, Postoperative Nausea and Vomiting
The Effect of Intraoperative Body Temperature on Postoperative Nausea and Vomiting in Pediatric Patients
The aim of our study was to investigate the effects of changes in body temperature in the perioperative period on postoperative nausea and vomiting.
- Trial name
- NCT04155931
- Testing
- body temperature measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Intraoperative Neurophysiological Monitoring, Complication
Patient Experiences of IONM and Outcomes
Resection of brain tumours forms a large proportion of work in brain surgery. One important aspect is to minimize damage to normal brain structures during this process. This improves patient outcomes and reduces complications.
- Conditions
- Intraoperative Neurophysiological Monitoring, Complication, Intraoperative Complications, Postoperative Complications
- Trial name
- IONM (NCT04443465)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Ephedrine, Norepinephrine
Postoperative Delirium After Intraoperative Ephedrine Versus Norepinephrine
This retrospective study aims to investigate the effects of norepinephrine compared to ephedrine, administered on the day of surgery, on the incidence of postoperative delirium.
- Conditions
- Ephedrine, Norepinephrine, Postoperative Delirium (POD)
- Trial name
- NCT06844201
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 10,000 people
- Sponsor
- Riverside University Health System Medical Center
Post Partum Hemorrhage
Intrauterine Misoprostol Versus Intravenous Oxytocin Infusion During Cesarean Delivery
Bleeding is still the major cause of mortality and morbidity in postpartum period. World health organization has reported 585000 deaths for pregnancy each year. Twenty five percent of cases die from post-partum bleeding.
- Trial name
- NCT03148574
- Testing
- Misoprostol, Oxytocin
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Assiut University
Spinal Fusion, Transfusion
Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications
Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients.
- Conditions
- Spinal Fusion, Transfusion, Pulmonary Complication
- Trial name
- NCT05661838
- Testing
- transfusion
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain Postoperative, Intraoperative Hemorrhage
Efficacy of Peritonsillar Dexmedetomidine Infiltration for Postadenotonsillectomy Pain
The purpose of the present study is the clinical assessment of the efficacy of preincisional peritonsillar infiltration of dexmedetomidine on postoperative pain relief in children undergoing adenotonsillectomy.
- Trial name
- NCT02013570
- Testing
- Dexmedetomidine
- Volunteers
- 71 people
- Sponsor
- TC Erciyes University
Morbidly Adherent Placenta
Morbidly Adherent Placenta, Diagnosis and Proper Management
The main idea of this study is to establish the diagnostic criteria for cases of morbidly adherent placenta (MAP) using different ultrasonographic modalities and compare this with intra-operative findings and postoperative…
- Trial name
- NCT05307016
- Testing
- Two dimensional ultrasonography power and color doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Awareness, Anesthesia
Validity of Perfusion Index to Evaluate the Level of General Anaesthesia in Children.
The aim of this study is to evaluate the validity of perfusion index to determine the level of anesthesia in comparison with auditory evoked potential in children undergoing tonsillectomy.
- Trial name
- PI/AAI (NCT03412214)
- Testing
- Perfusion index detected by pulse oximeter, AAI
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Assiut University
Liver Injury
Non-Operative Management of High Grade Blunt Hepatic Injury: Clinical Complications and the Role of Collateral Damage
Little is known about the role of collateral damage in patients with high grade liver injuries (LI). This retrospective single centre study investigates the safety of the non-operative management of patients with high grade blunt…
- Trial name
- NOMLI (NCT00694499)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Bern
Anesthesia Awareness
The Depth of Paediatric Anaesthesia: Observational Trial
Perioperative measurement of the Depth of anaesthesia is currently recommended part of daily anaesthesia good clinical practice. The optimal depth of anaesthesia measured by Bispectral index could be between 40-60.
- Trial name
- ANAPED (NCT05193747)
- Testing
- Anesthesia depth monitoring
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Prosthetic Complication, Prosthesis Failure, Dental
New Stereophotogrammetry System to Capture Complete-arch Impression
Patients in need of complete arch restorations will be treated with dynamic navigation system. Once the implants are positioned, a new system of stereophotogrammetry will record the implant positions to capture a precise…
- Trial name
- NCT06745232
- Testing
- FAST MAP
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Blood Loss, Surgical
Safety and Immunogenicity Study of Recombinant Thrombin (rThrombin) in Pediatric Participants
The objective of this study is to assess the safety and immunogenicity of recombinant thrombin (rThrombin) administered as an aid to hemostasis during burn wound excision and skin grafting in pediatric patients, newborn through…
- Trial name
- NCT00859547
- Testing
- rThrombin, 1000 IU/mL
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- ZymoGenetics
Intraoperative Awareness
The Impact of Maternal Sound on Awareness for Pediatric Patients Undergoing Cardiac Surgery
Awareness during anesthesia with intraoperative memory occurs when the patient is able to process information and produce specific responses to several stimuli.
- Trial name
- NCT02583295
- Testing
- Music sound, Maternal sound
- Where
- Egypt
- Volunteers
- 309 people
- Sponsor
- Assiut University
Pediatric Cardiac Surgery, Intraoperative Awareness
Closed Loop Propofol Administration in Pediatric Cardiac Surgery
The purpose of the study is to evaluate and compare the feasibility, efficacy and safety of IAADS (Improved Anaesthetic Agent Delivery System) for propofol anaesthesia against manual control using bispectral index in paediatric…
- Conditions
- Pediatric Cardiac Surgery, Intraoperative Awareness, Automated Drug Delivery
- Trial name
- NCT01600287
- Testing
- IAADS, Manual propofol administration
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Post Partum Hemorrhage
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery.
- Trial name
- SUMIROCBLOL (NCT05532215)
- Testing
- Misoprostol, Oxytocin
- Where
- Nigeria
- Volunteers
- 152 people
- Sponsor
- OZORI EBIOGBO STANLEY
Postoperative Pain, Inguinal Hernia Unilateral
Levobupivacaine and Postoperative Pain Relief
The study analysed direct levobupivacaine instillation in surgical wound and its effectiveness in postoperative pain control. Half participants received 0,5 % levobupivacaine and the other half received 0,9% saline solution
- Trial name
- NCT04869046
- Testing
- Instillation of levobupivacaine in surgical wound
- Where
- 2 sites in Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Hemorrhage, Surgical, Tonsillar Bleeding
TranExamic Atomized for Pediatric Post-Operative Tonsillectomy Hemorrhage: Pilot Study
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT06580509)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center at San Antonio